全文获取类型
收费全文 | 6686篇 |
免费 | 279篇 |
国内免费 | 42篇 |
专业分类
耳鼻咽喉 | 93篇 |
儿科学 | 309篇 |
妇产科学 | 69篇 |
基础医学 | 958篇 |
口腔科学 | 65篇 |
临床医学 | 443篇 |
内科学 | 1504篇 |
皮肤病学 | 124篇 |
神经病学 | 558篇 |
特种医学 | 228篇 |
外科学 | 1019篇 |
综合类 | 18篇 |
一般理论 | 1篇 |
预防医学 | 160篇 |
眼科学 | 108篇 |
药学 | 484篇 |
中国医学 | 23篇 |
肿瘤学 | 843篇 |
出版年
2023年 | 31篇 |
2022年 | 61篇 |
2021年 | 134篇 |
2020年 | 101篇 |
2019年 | 103篇 |
2018年 | 137篇 |
2017年 | 134篇 |
2016年 | 136篇 |
2015年 | 133篇 |
2014年 | 194篇 |
2013年 | 222篇 |
2012年 | 376篇 |
2011年 | 483篇 |
2010年 | 294篇 |
2009年 | 269篇 |
2008年 | 412篇 |
2007年 | 426篇 |
2006年 | 438篇 |
2005年 | 490篇 |
2004年 | 486篇 |
2003年 | 471篇 |
2002年 | 397篇 |
2001年 | 53篇 |
2000年 | 47篇 |
1999年 | 62篇 |
1998年 | 107篇 |
1997年 | 87篇 |
1996年 | 75篇 |
1995年 | 78篇 |
1994年 | 66篇 |
1993年 | 74篇 |
1992年 | 41篇 |
1991年 | 32篇 |
1990年 | 34篇 |
1989年 | 48篇 |
1988年 | 43篇 |
1987年 | 16篇 |
1986年 | 20篇 |
1985年 | 20篇 |
1984年 | 34篇 |
1983年 | 18篇 |
1982年 | 27篇 |
1981年 | 16篇 |
1980年 | 10篇 |
1979年 | 10篇 |
1978年 | 19篇 |
1977年 | 9篇 |
1976年 | 10篇 |
1975年 | 5篇 |
1970年 | 3篇 |
排序方式: 共有7007条查询结果,搜索用时 796 毫秒
111.
112.
Toshiaki Kogame Teruki Dainichi Yutaka Shimomura Miki Tanioka Kenji Kabashima Yoshiki Miyachi 《The Journal of dermatology》2014,41(12):1095-1097
Gap junction proteins are composed of 21 genes of the connexin (Cx) family. They play important roles in cell–cell contact by exchange of small molecules through hemichannels. Hence, mutations of Cx family genes affect various tissues of a body. The mutation of the GJA1 gene, which codes Cx43, causes oculodentodigital dysplasia (ODDD), commonly in an autosomal dominant manner with phenotypic variability. It has been believed that gene mutations causing truncation of the Cx43 C‐terminus is necessary and sufficient for palmoplantar keratosis (PPK) development in ODDD patients. Here, we report a case of an ODDD patient developing PPK with a GJA1 gene mutation (c.412G>A/p.Gly138Ser), which was previously reported in a case of ODDD without PPK and expected not to result in C‐terminal truncation of Cx43. This case suggests not only C‐terminal truncation, but also that a point mutation in the cytoplasmic region of Cx43 can cause PPK in ODDD patients. 相似文献
113.
114.
115.
116.
Acute myocardial infarction due to simultaneous spasm of 3 coronary arteries that worsened over time
Takuya Shimizu Ken Umetani Yu Murata Tomoko Harama Toshiaki Yano Aritaka Makino Keita Sano Masahiko Nakamura 《The American journal of emergency medicine》2018,36(3):528.e3-528.e5
Coronary artery spasm (CAS) rarely worsens from single-vessel to simultaneous multivessel CAS naturally, and simultaneous multivessel CAS leads to serious conditions such as cardiopulmonary arrest (CPA). A 77-year-old Japanese man who took medications for CAS was transferred to our hospital due to persistent chest pain. On arrival, his vital signs were stable, but his electrocardiogram (ECG) showed ST-segment elevation in leads II, III and aVF. Ventricular fibrillation developed suddenly. Although routine cardiopulmonary resuscitation (CPR) including intravenous administration of epinephrine was performed immediately, he could not be resuscitated. After initiation of percutaneous cardiopulmonary support (PCPS), there was a return of spontaneous circulation. His ECG showed exacerbation of myocardial ischemia with ST-segment elevation in leads I, II, III, aVL, aVF and V3–V6. Emergency coronary angiography revealed severe CAS of the right and left coronary arteries, which was relieved completely by intracoronary administration of nitrates. He was diagnosed with acute myocardial infarction due to simultaneous 3-vessel CAS that progressed over time. About 6 h after arrival, he developed hemodynamic instability and died. CAS worsened from single-vessel to simultaneous 3-vessel spasm, and intracoronary administration of nitrates was effective in relieving CAS, which was documented by the ECG and coronary angiogram. Since CAS can progress over time, nitrates must be administered immediately. When CAS leads to CPA, epinephrine may be ineffective in CPR because of its vasoconstrictive effect on coronary arteries; therefore, PCPS should be initiated, and intracoronary nitrates should be administered. 相似文献
117.
Impact of serum carbohydrate antigen 19‐9 level on prognosis and prediction of lymph node metastasis in patients with intrahepatic cholangiocarcinoma
下载免费PDF全文
![点击此处可从《Journal of gastroenterology and hepatology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
118.
119.
120.