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21.
目的探讨原发性高血压患者心电图心率校正QT间期(QTc)和贝那普利降压疗效之间的关系.方法采用前瞻性队列研究方法调查安徽A县899名高血压病患者的基线心电图、治疗15 d前后的血压变化及相关临床和流行病学特点等情况.结果 QTc和血压下降呈负相关.QTc每增加0.1秒1/2,收缩压和舒张压的下降值分别减少3.6 mmHg和3.3 mmHg,且差异均有显著性(P<0.05).将QTc三等分后,随着QTc等分的增加,收缩压和舒张压的下降值均逐渐减少,且差异具有显著性(P<0.05);将QTc等分后的变量放入方程中进行趋势性分析,发现在收缩压和舒张压组中的负相关关系具有显著性(P<0.05).随着QTc等级的增加,舒张压有效率逐渐降低,且有显著性差异(P<0.05),收缩压的效应关系不如舒张压明显.结论 QTc和贝那普利降压疗效呈负相关,对贝那普利短期降压疗效具有重要的预测价值. 相似文献
22.
不同剂量地塞米松鞘内注射治疗蛛网膜下腔出血头痛的临床研究 总被引:1,自引:0,他引:1
目的 探索地塞米松鞘内注射治疗蛛网膜下腔出血(SAH)头痛的适宜剂量。方法 所选病例分为4组,分别用0,5,10,20mg地塞米松鞘内注射观察止痛效果。结果 根据疗效判定标准,4组总有效率分别为25.00%,50.00%,92.31%,100.00%;头痛缓解时间随地塞米松(DXM)用量增加而延长。结论 DXM 10mg疗效比小剂量疗效高,与大剂量疗效;相同剂量越大缓解头痛时间越长。 相似文献
23.
A case of β-thalassemia major with a huge mass of hernatopoictic tissuc firmly attached tothe dura mater was reported This is the first case reported in China. 相似文献
24.
Wang Tao Liang Zhihou Sun Shenggang Cao Xuebing Peng Hai Cao Fei Liu Hongjin Tong E-tang 《华中科技大学学报(医学英德文版)》2003,23(2):145-147
Summary To investigate the distribution of possible novel mutations from parkin gene in variant subset of patients with Parkinson’s
disease (PD) in China and explore whether parkin gene plays an important role in the pathogenesis of PD, 70 patients were
divided into early-onset group and late-onset group; 70 healthy subjects were included as controls. Genomic DNA from 70 normal
controls and from those of PD patients were extracted from peripheral blood leukocytes by using standard procedures. Mutations
of parkin gene (exon 1–12) in all the subjects were screened by PCR-single strand conformation polymorphism (SSCP), and further
sequencing was performed in the samples with abnormal SSCP results, in order to confirm the mutation and its location. A new
missense mutation Gly284Arg in a patient and 3 abnormal bands in SSCP electrophoresis from samples of another 3 patients were
found. All the DNA variants were sourced from the samples of the patients with early-onset PD. It was concluded that Parkin
point mutation also partially contributes to the development of early-onset Parkinson’s disease in Chinese.
WANG Tao, male, born in 1961, Associate Professor
This work was supported by grants from the key program of the special scientific project of Scientific & Technologic Agency
of Hubei Province (Serial No. 2001AA308B01) and the Hygienic Research Project of Hygienic Agency of Hubei province (Serial
No. WJ 01529). 相似文献
25.
大鼠翼腭神经节SIF细胞的年龄变化 总被引:4,自引:1,他引:3
用醛诱发荧光法观察了不同年龄组大鼠翼腭神经节小强荧光(SIF)细胞的数量,发现出生1天时SIF细胞数量最少,1周内急剧增加,1-2周数量无明显,至4周数量继续增加,成年时数量最多,老年时比成年时无明显的数量变化,表明大鼠翼腭神经节SIF细胞的数量随年龄增长而增加。 相似文献
26.
A study on various symptoms of chronic hepatitis treated with radix astragali and its regulative effect to levels of serum hormone 下载免费PDF全文
Ke-zhou Liu Zhong-hang Tong Ming-tai Zhang Wei-zheng Gu Zhi-rong Huang Bi-he Shen Pei-ren Cai Gui-lang Zhu Wen-nan He Lan-sheng Feng Lie-ming Ding Zhi Chen Jian-hua Jin Xiu-zhi Zhang Qian-yan Yu Shui-jin Tong Ping Ye 《中国结合医学杂志》1995,1(2):118-121
Sixty-seven cases of chronic hepatitis were treated with Radix Astragali. After treatment (2-month course), the clinical improvement rate in 38 cases of the Stagnation of the Liver-Qi and Deficiency of the Spleen type was 92.1%, and in 26 cases of the Deficiency of Liver Yin and Kidney Yin type was 88.5%, more effective than in the control group (P<0.05). The regulative effect to the levels of serum hormone was observed in the patients of the Stagnation of the Liver-Qi and Deficiency of the Spleen type treated with this medicine. The results showed that the levels of serum triiodothyronine, estradiol (female) and testosterone (male) were increased after treatment (1.40±1.38 ng/dl, 129.30±1.23 pg/ml and 496.24±1.47 ng/dl). Pre-treatment levels were 1.22±1.49 ng/dl, 104.60±1.45 pg/ml and 398. 17±1.55 ng/dl respectively (P<0.05); however, the level of serum prolactin (2.75±4.46 ng/ml) was lower after treatment than before treatment (3.20±3.82 ng/ml,P<0.05). No obvious changes were observed in the levels of serum follicle stimulating hormone, luteinizing hormone, thyroid stimulating hormone, thyroxine, triiodothyronine uptake ratio and cortisol after treatment. 相似文献
27.
目的:观察吸入一氧化氮(NO)对心瓣膜置换术后肺动脉高压患者血流动力学的影响。方法:选择9例心瓣膜置换术后伴肺动脉高压的病人,吸入NO0.003%,观察三个时象点:吸入NO前;开始吸入NO后15分钟;停止吸入NO后15分钟。结果:吸入NO能显著降低肺动脉压和肺循环阻力指数(P<0.01),停止吸入NO15分钟后,肺动脉压和肺循环阻力指数恢复到原有水平。在整个观察过程中,心率、平均动脉压、中心静脉压、肺动脉楔压、体循环阻力指数和心脏指数均无显著变化(P>0.05)。结论:吸入NO具有选择性肺血管扩张作用,是治疗心瓣膜置换术后肺动脉高压的较理想药物。 相似文献
28.
The cases of 46 children who had been abused sexually an average of 2.6 years previously, were reviewed and the non-offending parents were interviewed with emphasis on how they viewed the professional persons who had seen their children, and their opinions of the legal processes that were instituted. The parents found most professional groups helpful, with officers from the Department of Youth and Community Services being seen as the least helpful. Twenty-one of the cases went to court; in 12 cases this resulted in a conviction, and prison sentences were imposed on six of the offenders. Children found the court experience distressing and most parents expressed dissatisfaction with the outcome of the court hearing. Children were more likely to be required to give evidence in court if the offender had legal representation. Persisting behavioural problems and poor school performance were more likely to occur in those cases in which there had been court hearings. A review of Police Department records of children who had attended the hospital for the management of sexual assault, showed that 10 of the 107 children who are now aged over 14 years, have themselves been convicted of violent crimes since their episode of sexual assault. Long-term intervention is required to help many of these children, some legal reforms are necessary to reduce the stress that they experience when there is a court hearing, and all the professional groups that are likely to become involved with the problem of the sexual abuse of children need to be better informed about its seriousness and consequences. 相似文献
29.
30.
目的:探讨山楂结块形成的机制,以指导预防和治疗。方法:配制以胃蛋白酶为基本液的模拟胃液,对60个山楂糊团和500g山楂糊进行酸凝实验。使用6%和8%浓度的碳酸氢钠溶液对酸凝后的山楂糊团、山楂糊做碱离解试验。设搅拌、非搅拌组和清水对照组作对比。结果:酸凝实验:山楂团硬度增加。清水对照组山楂团硬度明显低于酸凝组。散放入模拟胃液中的山楂糊相互接触处发生凝结,形态仍呈不规则片块状。碱离解实验:6h后碳酸氢钠溶液中均出现酸碱中和现象。非搅拌组:结块表面有碎屑脱落,至第10天碳酸氢钠溶液和清水中的结块均未自行碎解。搅拌组:搅拌时有较多碎屑脱落。第3天,1个结块碎解。至第10天,20个结块全部碎解。清水对照组:仅1个结块在第8天碎解。结论:山楂团酸凝后硬度增大。散放入的山楂糊酸凝后形态仍呈不规则片块状。碱溶液通过酸碱中和可使山楂结块表面松解,无外力作用时不能使结块碎解。 相似文献