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81.
Sakuraba H Fujiwara N Sasaki-Oikawa A Sakano M Tabata Y Otsu K Ishizeki K Harada H 《Journal of periodontal research》2012,47(1):81-88
Sakuraba H, Fujiwara N, Sasaki‐Oikawa A, Sakano M, Tabata Y, Otsu K, Ishizeki K, Harada H. Hepatocyte growth factor stimulates root growth during the development of mouse molar teeth. J Periodont Res 2012; 47: 81–88. © 2011 John Wiley & Sons A/S Background and Objective: It is well known that tooth root formation is initiated by the development of Hertwig’s epithelial root sheath (HERS). However, relatively little is known about the regulatory mechanisms involved in root development. As hepatocyte growth factor (HGF) is one of the mediators of epithelial–mesenchymal interactions in rodent tooth, the objective of this study was to examine the effects of HGF on the root development of mouse molars. Material and Methods: The HERS of mouse molars and HERS01a, a cell line originated from HERS, were used in this study. For detection of HGF receptors in vivo and in vitro, we used immunochemical procedures. Root development was assessed by implanting molar tooth germs along with HGF‐soaked beads into kidney capsules, by counting cell numbers in HERS01a cell cultures and by performing a 5′‐bromo‐2′‐deoxyuridine (BrdU) assay in an organ‐culture system. Results: HGF receptors were expressed in the enamel epithelium of molar germs as well as in HERS cells. HGF stimulated root development in the transplanted tooth germs, the proliferation of HERS01a cells in culture and HERS elongation in the organ‐culture system. Examination using BrdU revealed that cell proliferation in HERS was increased by treatment with HGF, especially that in the outer layer of HERS. This effect was down‐regulated when antibody against HGF receptor was present in the culture medium. Conclusion: Our results raise the possibility that HGF signaling controls root formation via the development of HERS. This study is the first to show that HGF is one of the stimulators of root development. 相似文献
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S. Mizuno H. Inoue A. Tanemura Y. Murata N. Kuriyama Y. Azumi M. Kishiwada M. Usui H. Sakurai M. Tabata R. Yamada N. Yamamoto K. Sugimoto K. Shiraki Y. Takei S. Isaji 《Transplantation proceedings》2014
Background
Biliary complications remain the leading cause of postoperative complications after living-donor liver transplantation (LDLT) in patients undergoing duct-to-duct choledochocholedochostomy. The aim of this study was to analyze the causes of these complications.Methods
One hundred eight patients who underwent LDLT with duct-to-duct biliary reconstruction at Mie University Hospital were enrolled in this study. The mean follow-up time was 58.4 months (range, 3–132). The most recent 18 donors underwent indocyanine green (ICG) fluorescence cholangiography for donor hepatectomy. The development of biliary complications was retrospectively analyzed. Biliary complications were defined as needing endoscopic or radiologic treatment.Results
Biliary leakages and strictures occurred in 6 (5.6%) and 15 (13.9%) of the recipients, respectively, and 3 donors (2.7%) experienced biliary leakage. However, since the introduction of ICG fluorescence cholangiography, we have not encountered any biliary complications in either donors or recipients. Biliary leakage was an independent risk factor for the development of biliary stricture (P = .013). Twelve (80%) of the 15 recipients with biliary stricture had successful nonoperative endoscopic or radiologic management, and 3 patients underwent surgical repair with hepaticojejunosotomy.Conclusions
Biliary leakage was an independent factor for biliary stricture. ICG fluorescence cholangiography might be helpful to reduce biliary complications after LDLT in both donors and recipients. 相似文献85.
Masahiko Noguchi MD Minoru Tabata MD Kotaro Obunai MD Kentaro Shibayama MD Joji Ito MD Hiroyuki Watanabe MD Fumiaki Yashima MD Yusuke Watanabe MD Toru Naganuma MD Motoharu Araki MD Futoshi Yamanaka MD Shinichi Shirai MD Hiroshi Ueno MD Kazuki Mizutani MD Akihiro Higashimori MD Kensuke Takagi MD Norio Tada MD Masanori Yamamoto MD Kentaro Hayashida MD 《Catheterization and cardiovascular interventions》2021,97(1):E113-E120
86.
Hiromu Hase MD Nobuhiro Yoshijima MD Ryo Yanagisawa MD Makoto Tanaka MD Hikaru Tsuruta MD Hideyuki Shimizu MD Keiichi Fukuda MD Toru Naganuma MD Kazuki Mizutani MD Masahiro Yamawaki MD Norio Tada MD Futoshi Yamanaka MD Shinichi Shirai MD Minoru Tabata MD Hiroshi Ueno MD Kensuke Takagi MD Yusuke Watanabe MD Masanori Yamamoto MD Kentaro Hayashida MD PhD FESC FACC FJCS OCEAN-TAVI Investigators 《Catheterization and cardiovascular interventions》2021,97(6):E875-E886
87.
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Masakazu Yamamoto Masahiro Yoshida Junji Furuse Keiji Sano Masayuki Ohtsuka Shingo Yamashita Toru Beppu Yukio Iwashita Keita Wada Takako Eguchi Nakajima Katsunori Sakamoto Koichi Hayano Yasuhisa Mori Koji Asai Ryusei Matsuyama Teijiro Hirashita Taizo Hibi Nozomu Sakai Tsutomu Tabata Hisato Kawakami Hiroyuki Takeda Takuro Mizukami Masato Ozaka Makoto Ueno Yoichi Naito Naohiro Okano Takayuki Ueno Susumu Hijioka Satoru Shikata Tomohiko Ukai Steven Strasberg Michael G. Sarr Palepu Jagannath Tsann‐Long Hwang Ho‐Seong Han Yoo‐Seok Yoon Hee Jung Wang Shao‐Ciao Luo Ren Adam Mariano Gimenez Olivier Scatton Do‐Youn Oh Tadahiro Takada 《Journal of hepato-biliary-pancreatic sciences》2021,28(1):1-25
89.
N Ishikawa T Fuchigami T Matsumoto H Kobayashi Y Sakai H Tabata N Takubo S Yamamoto M Nakanishi K Tomioka M Fujishima 《Rheumatology (Oxford, England)》2002,41(1):72-77
OBJECTIVE: The aim of this study was to investigate the impact of Helicobacter pylori infection on clinical features in patients with rheumatoid arthritis (RA) under medication with non-steroidal anti-inflammatory drugs. METHODS: One hundred and eighty-four patients with RA were tested for the presence of H. pylori infection. Clinical features and gastroduodenal lesions were compared between H. pylori-positive and -negative patients. RESULTS: One hundred and thirteen patients were positive and 71 patients were negative for H. pylori. The age, severity of RA, prevalence of gastrointestinal symptoms and gastroduodenal lesions and the class of gastroprotective drugs were not different between the two groups. Reflux oesophagitis was less frequent and sulphasalazine was less frequently administered in the H. pylori-positive group. CONCLUSIONS: The severity of RA, prevalence of gastroduodenal lesions other than reflux oesophagitis and the application of gastroprotective drugs do not seem to depend upon H. pylori infection in RA patients. Sulphasalazine may be protective against H. pylori infection. 相似文献
90.
Terumi Kamisawa Ikuo Tabata Tomoaki Isawa Kouji Tsuruta Atsutake Okamoto Morio Koike 《Journal of gastrointestinal cancer》1995,18(1):67-70
Summary Pleomorphic carcinoma of the pancreas is a rare, histologically characterized pancreatic tumor with a rapid and fatal course.
We report a case of a resected pleomorphic carcinoma located in the body of the pancreas in a 61-yr-old male. Histological
analysis of the resected specimen revealed the coexistence of pleomorphic carcinoma with adenocarcinoma, but the recurrent
tumors at autopsy 20 mo later were only of the adenocarcinomatous type. Cells in the adenocarcinomatous component showed a
diffuse reactivity for CA19-9, CEA, and cytokeratin, and a focal reactivity for vimentin. In contrast, vimentin was diffusely
expressed in pleomorphic lesion. Adenocarcinoma at autopsy expressed CA19-9, CEA, and cytokeratin, but not vimentin. These
findings suggest that the recurrent adenocarcinoma may have developed as a consequence of sequential change in the nature
of the tumor. 相似文献