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排序方式: 共有316条查询结果,搜索用时 15 毫秒
21.
Automated Data Abstraction of Cardiopulmonary Resuscitation Process Measures for Complete Episodes of Cardiac Arrest Resuscitation 下载免费PDF全文
22.
Kumar V San KP Idwan A Shah N Hajar S Norkahfi M 《Journal of Forensic and Legal Medicine》2007,14(3):151-154
The main aim of this study is to determine the causes and the epidemiological aspects of sudden natural deaths. Data were collected from 545 sudden natural autopsies in UMMC, Kuala Lumpur over a five-year period, from 1st January 2000 to 31st December 2004. There were 475 males and 70 females. The largest number of sudden natural deaths was in the age group of 41-50 years. 35.8%, 30.5% and 11.7% of the patients were Chinese, Indian and Malay, respectively. A majority of the patients were married (59.8%) and came from the semiskilled-unskilled group (30.6%). The monthly distribution was almost constant. Cardiovascular diseases were the most important cause contributing 64.9% in sudden natural deaths. 相似文献
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Ng Sean Ming Sheng Low Rebecca Hoskin Annette K. Rousselot Andres Gunasekeran Dinesh Visva Natarajan Sundaram Sundar Gangadhara Chee Caroline Ka Lin Mishra Chitaranjan Sen Parveen Pradhan Eli Irawati Yunia Kamalden Tengku Ain Shah Mehul Yan Hua Woreta Fasika A. Subramanian Prem S. Kuhn Ferenc Watson Stephanie L. Agrawal Rupesh 《Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie》2022,260(4):1055-1067
Graefe's Archive for Clinical and Experimental Ophthalmology - Ophthalmic trauma is a leading cause of preventable monocular blindness worldwide. The prevalence of ophthalmic trauma varies... 相似文献
24.
Harmin Sulistiyaning Titah Siti Rozaimah Sheikh Abdullah Idris Mushrifah Nurina Anuar Hassan Basri Muhammad Mukhlisin 《Bulletin of environmental contamination and toxicology》2013,90(6):714-719
Wilting, especially of the leaves, was observed as an initial symptom of arsenate [As(V)] to Ludwigia octovalvis (Jacq.) P. H. Raven. The plants tolerated As(V) levels of 39 mg kg?1 for as long as 35 days of exposure. After 91 days, the maximum concentration of As uptake in the plant occurred at As(V) concentration of 65 mg kg?1 while As concentration in the stems, roots and leaves were 6139.9 ± 829.5, 1284.5 ± 242.9 and 1126.1 ± 117.2 mg kg?1, respectively. In conclusion, As(V) could cause toxic effects in L. octovalvis and the plants could uptake and accumulate As in plant tissues. 相似文献
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Induction of Apoptosis by Acanthaster planci sp., and Diadema setosum sp., Fractions in Human Cervical Cancer Cell Line,HeLa 下载免费PDF全文
Gul-e-Saba ChaudhryMurni IslamiahMuhammad Naveed ZafarKamariah BakarNurAsniza AzizJasnizat SaidinYeong Yik SungTengku Sifzizul Tengku Muhammad 《Asian Pacific journal of cancer prevention》2021,22(5):1365-1373
Cancer is an uncontrolled multiplication of cells. The desire efficacy and severe toxicity of current anticancer drugs urge exploring and investigating a better alternative to existing chemotherapeutics. Natural products of marine origin are excellent sources of potential new drugs of enhanced biological activities. Objectives: Thus, the cytotoxic effects along with investigating the mode of cell death exerted by fractions, AP-9, AP-THR, DS-8 and DS-9 fraction of Acanthaster planci, Diadema setosum sp., on the human cervical cancer cell line, HeLa. Methods: The cytotoxicity of fractions has determined by using an MTS assay. The early and late apoptosis was studied by using the High content Screening (HCS) instrument. Results: The four fractions produced effective cytotoxicity effects with IC50 values at 72hr of less than 20 μg/ml in the order of AP-9 > DS-9 > APTHR-9 > DS-8. The fraction s exhibited cytotoxicity via mediating apoptotic mode of cell death. The early apoptosis by exposure of phosphatidylserine to the outer leaflet of the plasma membrane and late apoptosis due to the presence of green stain (DNA fragmentation) in treated cells. Conclusion: The potent bioactive compounds might be responsible for inducing apoptosis in cancer cells and, thus, the potential to be a successful candidate for exploring upcoming chemotherapeutic drugs. 相似文献
27.
Plasma Circulating Mirnas Profiling for Identification of Potential Breast Cancer Early Detection Biomarkers 下载免费PDF全文
A Rashid JusohSivanesan Vijaya MohanTan Lu PingTengku Ahmad Damitri Al Astani Bin Tengku DinJuhara Haron Roslini Che RomliHasnan JaafarSiti Norasikin NafiTuan Ismail Tuan SalwaniMaya Mazuwin Yahya 《Asian Pacific journal of cancer prevention》2021,22(5):1375-1381
Objective: This study aimed to characterize the miRNA expression profiles from plasma samples of our local breast cancer patients in comparison to healthy control by using miRNA PCR Array. Methods: In this study, plasma miRNA profiles from eight early-stage breast cancer patients and nine age-matched (± 2 years) healthy controls were characterized by miRNA array-based approach, followed by differential gene expression analysis, Independent T-test and construction of Receiver Operating Characteristic (ROC) curve to determine the capability of the assays to discriminate between breast cancer and the healthy control. Results: Based on the 372-miRNAs microarray profiling, a set of 40 differential miRNAs was extracted regarding to the fold change value at 2 and above. We further sub grouped 40 miRNAs of breast cancer patients that were significantly expressed at 2-fold change and higher. In this set, we discovered that 24 miRNAs were significantly upregulated and 16 miRNAs were significantly downregulated in breast cancer patients, as compared to the miRNA expression of healthy subjects. ROC curve analysis revealed that seven miRNAs (miR-125b-5p, miR-142-3p, miR-145-5p, miR-193a-5p, miR-27b-3p, miR-22-5p and miR-423-5p) had area under curve (AUC) value > 0.7 (AUC p-value < 0.05). Overlapping findings from differential gene expression analysis, ROC analysis, and Independent T-Test resulted in three miRNAs (miR-27b-3p, miR-22-5p, miR-145-5p). Cohen’s effect size for these three miRNAs was large with d value are more than 0.95. Conclusion: miR-27b-3p, miR-22-5p, miR-145-5p could be potential biomarkers to distinguish breast cancer patients from healthy controls. A validation study for these three miRNAs in an external set of samples is ongoing. 相似文献
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Edgar KOYOC-CARDE?A Anuar MEDINA-BARREIRO Francisco Javier ESCOBEDO-ORTEGóN Jorge Carlos RODRíGUEZ-BUENFIL Mario BARRERA-PéREZ Enrique REYES-NOVELO Juan CHABLé-SANTOS Celia SELEM-SALAS Gonzalo VAZQUEZ-PROKOPEC Pablo MANRIQUE-SAIDE 《Revista do Instituto de Medicina Tropical de S?o Paulo》2015,57(3):269-272
This study longitudinally investigated the association between Triatoma
dimidiata infestation, triatomine infection with Trypanosoma
cruzi and household/backyard environmental characteristics in 101
homesteads in Molas and Yucatan, Mexico, between November 2009 (rainy season) and May
2010 (dry season). Logistic regression models tested the associations between insect
infestation/infection and potential household-level risk factors. A total of 200
T. dimidiata were collected from 35.6% of the homesteads, mostly
(73%) from the peridomicile. Of all the insects collected, 48% were infected with
T. cruzi. Infected insects were collected in 31.6% of the
homesteads (54.1% and 45.9% intra- and peridomiciliary, respectively). Approximately
30% of all triatomines collected were found in chicken coops. The presence of a
chicken coop in the backyard of a homestead was significantly associated with both
the odds of finding T. dimidiata (OR = 4.10, CI 95% = 1.61-10.43,
p = 0.003) and the presence of triatomines infected with
T. cruzi (OR = 3.37, CI 95% = 1.36-8.33, p =
0.006). The results of this study emphasize the relevance of chicken coops as a
putative source of T. dimidiata populations and a potential risk for
T. cruzi transmission. 相似文献
30.