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951.
This study analyses distinct trajectories of vital exhaustion (VE; a measure of mental health incorporating signs of stress and depression) over a period of 15 years in healthy adults and investigates further the consequences for markers of low‐grade inflammation as indicators of cardiovascular disease risk. Data of 341 participants of the Amsterdam Growth and Health Longitudinal Study were utilized. VE was measured by the Maastricht Questionnaire. Markers of low‐grade inflammation included interleukin‐6, interleukin‐8 and tumour necrosis factor‐α. Distinct trajectories of VE were obtained by latent class growth models, and consequences for markers of low‐grade inflammation of the trajectories were analysed by linear regressions. We found comparable trajectories of VE for men and women; a ‘never vitally exhausted’ subgroup (16.9% and 25.1%, respectively), a ‘stable preclinical VE’ subgroup (51.7% and 68.1%) and a ‘chronic VE state’ subgroup (31.5% and 6.7%). The subgroups had similar levels of the markers investigated. This study is the first to analyse VE longitudinally in healthy adults and indicates that although distinct trajectories of VE were identified, differential consequences for cardiovascular disease risk were unapparent. Copyright © 2013 John Wiley & Sons, Ltd. 相似文献
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Matti Rautalahti Lea Hyvönen Demetrius Albanes Anna‐Maija Lampi Pekka Koivistoinen Jarmo Virtamo 《Nutrition and cancer》2013,65(3-4):247-251
The effect of sampling site and proximity of malignant tumor on the relative fatty acid composition of human breast adipose tissue was studied in 10 cases of breast cancer. The four anatomic quadrants of breast did not statistically significantly differ from each other in relation to any of the 30 fatty acids studied. Proximity of the malignant tumor did not affect the relative fatty acid composition of fat when compared with more distant sampling sites. Representative samples of breast adipose tissue for fatty acid composition analysis can be obtained from tissue adjacent to the tumor. 相似文献
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Insecticidal activity of a recombinant knottin peptide from Loxosceles intermedia venom and recognition of these peptides as a conserved family in the genus
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![点击此处可从《Insect molecular biology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
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Alberto Prats‐Galino Martin Čapek Miguel A. Reina Erika Cvetko Barbora Radochova R. Shane Tubbs Marija Damjanovska Tatjana Stopar Pintarič 《Clinical anatomy (New York, N.Y.)》2018,31(3):424-431
The general microscopic characteristics of nerves are described in several textbooks of histology, but the specific microanatomies of most nerves that can be blocked by anesthesiologists are usually less well known. Our objective was to evaluate the 3D reconstruction of nerve fascicles from optical projection tomography images (OPT) and the ability to undertake an internal navigation exploring the morphology in detail, more specifically the fascicular interconnections. Median and lingual nerve samples were obtained from five euthanized piglets. OPT images of the samples were acquired and 3D reconstruction was performed. The OPT technique revealed the inner structure of the nerves at high resolution, including large and small fascicles, perineurium, interfascicular tissue, and epineurium. The fascicles were loosely packed inside the median nerve and more densely so in the lingual nerve. Analysis of the 3D models demonstrated that the nerve fascicles can show six general spatial patterns. Fascicular interconnections were clearly identified. The 3D reconstruction of nerve fascicles from OPT images opens a new path for research into the microstructure of the inner contents of fascicular nerve groups and their spatial disposition within the nerve including their interconnections. These techniques enable 3D images of partial areas of nerves to be produced and could became an excellent tool for obtaining data concerning the 3D microanatomy of nerves, essential for better interpretation of ultrasound images in clinical practice and thus avoiding possible neurological complications. Clin. Anat. 31:424–431, 2018. © 2017 Wiley Periodicals, Inc. 相似文献
959.
Osseoinductive elements for promoting osseointegration around immediate implants: a pilot study in the foxhound dog
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![点击此处可从《Clinical oral implants research》网站下载免费的PDF全文](/ch/ext_images/free.gif)
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Rupioid lesions,PLEVA and superposition phenomenon in malignant syphilis: two case reports in HIV‐infected patients
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