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41.
Moiz B Moatter T Hashmi MR Hashmi N Kauser T Nasir A Khurshid M 《Annals of hematology》2008,87(5):385-389
Various hemoglobinopathies have been reported from Pakistan excepting the rare ones like hemoglobin Q India. Our purpose of
study was to identify the mutation (α 1 64 aspartate to histidine) through amplification restriction mutation system-polymerase
chain reaction (ARMS-PCR) in patients where hemoglobin Q has been detected via high performance liquid chromatography (HPLC)
and also to evaluate the cost effectiveness of the two technologies. All patients irrespective of age and gender who underwent
HPLC for identification of their hemoglobin variant during January 1, 2006 to January 30, 2007 were studied. The blood samples
with unknown peak at a retention time of 4.7 min were evaluated at the molecular level. Analysis of HPLC tracings of 11,008
subjects over a thirteen-month period identified ten individuals with hemoglobin Q. Male to female ratio was 1:1.5 and their
age was variable ranging from 1 to 49 (mean 22.8) years. The mean hemoglobin level was 11.3 g/dl while MCV (fl) and MCH (pg)
were 73.0 and 20.8 respectively. HPLC showed an unknown peak of 17.7% which was detected as Hb Q. ARMS based PCR showed Hb
Q specific product of 370 bp and also an amplified product of 766 bp as the control fragment in these samples. This is the
first ever report that documents the presence of Hb Q India (α 64 Asp to His) in Pakistani population. We recommend that HPLC
be used as a useful screening tool especially in developing countries where PCR facilities may not be accessible. 相似文献
42.
A Recessively Inherited Risk Locus on Chromosome 13q22-31 Conferring Susceptibility to Schizophrenia
Tariq Mahmood Mohammed E El-Asrag James A Poulter Alastair G Cardno Anneka Tomlinson Sophia Ahmed Ahmed Al-Amri Jamshid Nazari Joanna Neill Rifka S Chamali Nancy Kiwan Suhaila Ghuloum Hamid A Alhaj Juliette Randerson Moor Shabana Khan Hassen Al-Amin Colin A Johnson Peter Woodruff Iain D Wilkinson Manir Ali Steven J Clapcote Chris F Inglehearn 《Schizophrenia bulletin》2021,47(3):796
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Tariq Khurshid Ahmad 《Proceedings of the National Academy of Sciences, India. Section B.》2015,85(2):693-703
Proceedings of the National Academy of Sciences, India Section B: Biological Sciences - Small ruminants are the host to different species of gastrointestinal nematodes and their epidemiology... 相似文献
48.
Singh Simron Dey Chris Kennecke Hagen Kocha Walter Maroun Jean Metrakos Peter Mukhtar Tariq Pasieka Janice Rayson Daniel Rowsell Corwyn Sideris Lucas Wong Ralph Law Calvin 《Annals of surgical oncology》2015,22(8):2685-2699
Annals of Surgical Oncology - Pancreatic neuroendocrine tumors (pNETs) are rare heterogeneous tumors that have been steadily increasing in both incidence and prevalence during the past few decades.... 相似文献
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