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61.
62.
Huey-Juan Lin Poh-Shiow Yeh Tsung-Chia Tsai Tain-Junn Cheng Dershin Ke Kao-Chang Lin Jih-Gong Ho Chia-Yu Chang 《Journal of clinical neuroscience》2007,14(1):17-21
Using a prospective hospital-based registry, 146 patients with transient ischaemic attack (TIA) were compared with 376 patients with minor first-ever ischaemic stroke with respect to the 3-month risk of subsequent vascular events, in order to clarify the distinctions between the disease entities. All patients were enrolled within 48 h of onset. The risk factor distribution for the two groups was comparable, except that the TIA patients had more previous TIAs. Large artery atherosclerosis (34%) and small vessel occlusion (32%) were the main aetiologies in the TIA group, whereas small vessel occlusion (49%) was the major cause in the stroke group. The 3-month risk of combined endpoints of stroke, myocardial infarction, and vascular death for TIA patients was higher than that for the minor stroke group (15.1% vs. 3.2%; hazard ratio 4.6, 95% confidence interval 2.3-9.3 in multivariate analysis). Large artery atherosclerosis and male sex were the other significant predictors. TIA may demand more urgent management than minor stroke. The fact that aetiology is a predictor, highlights the need for rapid diagnostic tests to establish pathogenesis. 相似文献
63.
报道成功救治38例产科DIC的临产资料,发病诱因以妊高征、死胎,胎盘早剥多见。治疗上以病因治疗与肝素抗凝治疗为主,主张早期、小量,快速的肝素疗法,每日剂量不得超过50mg。积极抗休克,辅以输血及抗纤溶综合治疗措施,不失时机地切除子宫。 相似文献
64.
肾细胞癌伴静脉癌栓15例临床分析 总被引:5,自引:1,他引:4
1985~1994年治疗肾细胞癌伴静脉癌栓15例。按癌栓水平分为肾型10例,肝下型4例,肝上型1例。B超和CT检查总确诊率73%。手术14例均完整取出癌栓,术后13例接受5-FU加MMC方案化疗。随访3个月~5年,1例肝下型和2例肾型无瘤存活分别36、43、52个月,余均在术后2年内死亡。认为B超与CT互补应用可基本确诊静脉癌栓,除肝上型和已有血管壁浸润者外大部分癌栓可采用松解游离同时渐渐拉出的方式取出,癌栓水平除肝上型外对预后影响不大。 相似文献
65.
临床输液监控系统的设计 总被引:5,自引:0,他引:5
本文针对临床输液过程中出现的漏、停、输液速度改变等各种问题,讨论了一由单台微机和多个单片机通讯实现的多床输液自动监控、自动反应、自动报答系统的可行性,并给出了主要部分的硬件、软件设计方法。 相似文献
66.
白细胞介素-10诱导的大鼠树突状细胞体外免疫功能的研究 总被引:19,自引:7,他引:12
目的 研究白细胞介素 10 (IL 10 )诱导的大鼠未成熟树突状细胞 (imDCs)体外诱导免疫耐受的可行性。方法 在经典诱导方案的基础上 ,应用IL 10 ( 10 μg/L)抑制大鼠骨髓来源DCs的成熟 (IL 10组 ,10例 ) ,并设对照组 (IL 4组 ,10例 )。培养期间观察DCs形态 ,检测DCs表型、摄取抗原能力、体外免疫功能及培养上清细胞因子水平。结果 与IL 4组比较 ,IL 10组DCs细胞表面CD80 、CD86及OX6低度表达 ( 2 5 .3 %、42 .4%、3 2 .3 % ) ,吞噬能力较强 ( 81.9) ,刺激同种异体淋巴细胞增殖能力下降 ,该淋巴细胞具有抗原特异性低反应性 ;培养上清中IL 12水平 ( 4 0 6.5pg/L)及初次MLR培养上清IL 2水平 ( 2 45 .4ng/L)均较低 ,差异有非常显著性 (P <0 .0 1)。 结论 IL 10作用的大鼠imDCs具有诱导免疫耐受的应用价值。 相似文献
67.
Ming-I. Hsu Paul Kolm John Leete Ke Wen Dong Suheil Muasher Sergio Oehninger 《Journal of assisted reproduction and genetics》1998,15(8):496-503
Purpose:
Our purpose was to examine implantation of singleton pregnancies achieved following various assisted reproductive technologies (ARTs) through the appearance and rising titers of serum human chorionic gonadotropin (hCG) levels.
Methods:
A total of 114 singleton pregnancies resulting from in vitro fertilization and intrauterine insemination was analyzed. Patients were divided into five groups according to the type of ovarian stimulation protocol [gonadotropin stimulation with/without the use of gonadotropin-releasing hormone agonist (GnRHa), long protocol, or flare-up technique] and to the day of embryo transfer (day 2 or day 3 after oocyte retrieval). Serial serum hCG levels were measured between 10 and 25 days after fertilization and log-transformed. Linear regression analyses were performed and extrapolated to hCG = 10 mIU/ml (hCG
10
), which was used as an estimate of detectable implantation. The slopes of the regression lines were used to estimate the rising speed of hCG.
Results:
There were no significant differences in the days of hCG in maternal serum to reach 10 mIU/ml (implantation) or in the slopes of the regression lines for all five studied groups.
Conclusions:
The appearance of hCG in maternal serum was used to assess the time of clinically detectable implantation. Furthermore, because hCG production is a marker of trophoblastic activity, its serum doubling time was used as an indicator of embryo quality. Results showed that in various ART protocols with and without GnRHa, there were no significant differences in implantation time or embryo quality. Embryo development in early pregnancy follows a preprogrammed-timing schedule and depends mainly on the embryonic age of the health, successfully implanted conceptus. 相似文献
68.
Summary;To investigate the distribution of possible novel mutations from parkin gene in variant sub-set of patients with Parkinson’s disease(PD)in China and explore whether parkin gene plays an im-portant role in the pathogenesis of PD,70 patients were divided into early-onset group and late-onsetgroup; 70 healthy subjects were included as controls.Genomic DNA from 70 normal controls andfrom those of PD patients were extracted from peripheral blood leukocytes by using standard proce-dures.Mutations of parkin gene(exon 1—12)in all the subjects were screened by PCR-single strandconformation polymorphism(SSCP),and further sequencing was performed in tue samples with ab-normal SSCP results,in order to confirm the mutation and its location.A new missense mutationGly284Arg in a patient and 3 abnormal bands in SSCP electrophoresis from samples of another 3 pa-tients were found.All the DNA variants were sourced from the samples of the patients with early-on-set PD.It was concluded that Parkin point mutation a 相似文献
69.
手部创伤性骨关节缺损的处理 总被引:4,自引:0,他引:4
治疗手部骨关节缺损常采用植骨内固定、关节融合、关节成形及关节置换等方法.为总结经验,对1989年以来101例手部创伤性骨与关节缺损进行分析。单纯掌、指骨缺损39例,行直接短缩对位,克氏针内固定6例,1例发主骨不连;对33例缺损较大者用自体骨块植入克氏针交叉内固定,部分病例同时植人RBX或异体骨粒,10例发生延迟愈合,余全部正常愈合。骨与关节部分或完全缺损62例,采用关节成形术46例,其中以肋软骨移植效果最好,骨膜移植次之,筋膜衬垫或硅胶膜植入法较差;行关节融合术11例.均达顺利融合;采用自体关节置换5例,均成活,术后关节活动度均>70°。我们认为:自体骨块植入克氏针交叉内固定,必要时植入RBX骨粒.是治疗手部创伤性骨缺损的有效方法。关节缺损应按关节的重要性,分别采用关节融合术、关节成形术或关节置换术。 相似文献
70.