全文获取类型
收费全文 | 36173篇 |
免费 | 1620篇 |
国内免费 | 297篇 |
专业分类
耳鼻咽喉 | 266篇 |
儿科学 | 686篇 |
妇产科学 | 417篇 |
基础医学 | 4800篇 |
口腔科学 | 1006篇 |
临床医学 | 2115篇 |
内科学 | 8979篇 |
皮肤病学 | 869篇 |
神经病学 | 2453篇 |
特种医学 | 1255篇 |
外科学 | 6476篇 |
综合类 | 145篇 |
一般理论 | 1篇 |
预防医学 | 990篇 |
眼科学 | 630篇 |
药学 | 2094篇 |
中国医学 | 123篇 |
肿瘤学 | 4785篇 |
出版年
2024年 | 25篇 |
2023年 | 202篇 |
2022年 | 537篇 |
2021年 | 880篇 |
2020年 | 450篇 |
2019年 | 648篇 |
2018年 | 845篇 |
2017年 | 657篇 |
2016年 | 774篇 |
2015年 | 801篇 |
2014年 | 1079篇 |
2013年 | 1373篇 |
2012年 | 2230篇 |
2011年 | 2608篇 |
2010年 | 1481篇 |
2009年 | 1216篇 |
2008年 | 2234篇 |
2007年 | 2467篇 |
2006年 | 2315篇 |
2005年 | 2489篇 |
2004年 | 2395篇 |
2003年 | 2402篇 |
2002年 | 2398篇 |
2001年 | 357篇 |
2000年 | 298篇 |
1999年 | 428篇 |
1998年 | 584篇 |
1997年 | 469篇 |
1996年 | 442篇 |
1995年 | 384篇 |
1994年 | 332篇 |
1993年 | 303篇 |
1992年 | 211篇 |
1991年 | 191篇 |
1990年 | 187篇 |
1989年 | 167篇 |
1988年 | 147篇 |
1987年 | 108篇 |
1986年 | 102篇 |
1985年 | 89篇 |
1984年 | 107篇 |
1983年 | 86篇 |
1982年 | 73篇 |
1981年 | 88篇 |
1980年 | 83篇 |
1979年 | 61篇 |
1978年 | 43篇 |
1977年 | 30篇 |
1976年 | 25篇 |
1975年 | 25篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
41.
42.
Kazue Shimmoto Shinichiro Ushigome Takashi Nikaido YaSUShi Kikuchi Naoaki Kobayashi Yohji Yamazaki 《Pediatric hematology and oncology》1991,8(2):147-157
A case is reported of Wilms' tumor associated with multiple pulmonary metastases histologically showing maturation of the tumor cells at 9 years after the resection of the primary tumor and intensive therapy. A huge tumor of a 22-month-old patient's right kidney was resected. The tumor was diagnosed as Wilms' tumor of mesenchymal type (stage 1), which consisted of predominantly immature mesenchymal tissue including rhabdomyoblasts, smooth muscle and fibrous tissue, and few blastemal and epithelial components. Intensive preoperative and postoperative chemotherapy with actinomycin D and vincristine and postoperative irradiation therapy totaling 16 Gy were carried out. The patient was regularly followed up uneventfully until 9 years after the surgery. On routine chest x ray at the age of 10 years 11 months, multiple pulmonary nodules were found. The excised nodules from the bilateral lungs disclosed similar histology, exclusively composed of dense collagen bundles and fibrocytes intermingled with mature striated muscle bundles. No immature tumor components were detected. The possible effect of intensive therapy in this maturation was stressed, although spontaneous benign differentiation of tumor cells cannot be excluded. 相似文献
43.
Takashi Hineno M.D. Mutsuhiko Mizobuchi M.D. Oh-ichi Nishimatsu M.D. Jun Horiguchi M.D. Yasuo Kakimoto M.D. 《Psychiatry and clinical neurosciences》1994,48(3):583-587
Abstract: Studies on the circadian rhythm of urine excretion in healthy men have demonstrated that the maximal urine flow occurs in the early afternoon and the minimal around midnight. In this study, an abnormality in the variation of urine volume was found in parkinsonian patients. Urine samples were collected during daytime (9:00–21:00) and nighttime (21:00–9:00). Fifteen healthy control subjects were examined and found to excrete 60% during the daytime and 40% during the nighttime of the total urine volume. Sixteen parkinsonian patients excreted 43% during the daytime and 57% during the nighttime. In contrast to the control subjects, the parkinsonian patients excreted a smaller volume of their urine during the daytime than during the nighttime. This finding might be related to the degeneration of dopaminergic and/or nondopaminergic neurons in the brain which control urinary excretion. 相似文献
44.
Patterns of Age-Related Immunologic Changes 总被引:1,自引:0,他引:1
Takashi Makinodan Ph.D. 《Nutrition reviews》1995,53(4):S27-S34
45.
Hideto SAKAI Kiichiro JINDE Noboru SAOTOME Wei SUNG Mitsunori YAGAME Yasuo NOMOTO Masanobu MIYAZAKI Takashi HARADA 《Nephrology (Carlton, Vic.)》1997,3(1):91-94
Summary: In situ hybridization of mRNA for collagen IV, collagen VI, stromelysin (MMP-3) and TIMP1 was examined in renal biopsy specimens from patients with IgA nephropathy (IgAN) or diabetic nephropathy with various degrees of tissue damage. The majority of cells in the glomeruli expressed these mRNA almost simultaneously, but a few cells demonstrated positive expression for only one of these probes. There was a parallel relationship between the degree of tissue damage and that of mRNA expressions of these probes in patients with IgAN, while patients with diabetic nephropathy showed a reverse relationship between these two parameters. It is concluded that patients with mesangial proliferative glomerulonephritis expressed mRNA for collagen collagenase and its inhibitor in the glomeruli in parallel with the progress of tissue damage. In contrast, glomerular samples from patients with diabetic nephropathy showed that there was an inverse relationship between tissue damage and expression of mRNA. It is concluded that expression of collagen, collagenase and its inhibitor parallels the progression of glomerular changes in IgAN, but such parallel expression was not observed in patients with diabetic nephropathy. 相似文献
46.
We report the surgical results of 13 accessory nerve neurotizations in brachial plexus birth palsy. The mean age at operation was 5.9 months. The accessory nerve was transferred to three C5 roots, to three C6 roots, to four posterior division of the middle trunks, to one musculocutaneous nerve, and to two suprascapular nerves. Sixty-seven percent of the cases acquired M4 or more in the deltoid muscle, 88% in the infraspinatus muscle, and 100% in the biceps brachii muscle. Twenty-five percent of the cases acquired M4 or more in the triceps brachii muscle and the wrist extensor muscles. These results were much better than formerly reported for adult cases by other authors. No functional compromise of the trapezius muscle was noted. The accessory nerve neurotization can be used safely and effectively in neurosurgical reconstruction of the brachial plexus palsy in infants. © 1994 Wiley-Liss, Inc. 相似文献
47.
Masafumi Yamaguchi Shinsuke Mii Takashi Kai Hisanobu Sakata Akira Mori 《Surgery today》1997,27(9):863-867
Two elderly women complaining of intermittent claudication complicated with persistent sciatic artery are herein reported.
A direct femoral arteriogram showed hypoplasty of the superficial femoral artery and an unnatural anatomical relationship
between the distal superficial femoral artery and the proximal popliteal artery, thus suggesting the presence of persistent
sciatic artery. The diagnosis of persistent sciatic artery was finally made based on the aortography findings including the
iliac arterial system and computed tomography (CT) scan. Magnetic resonance imaging (MRI) was helpful to demonstrate the entire
image of this anomaly in cases with non-thrombolized sciatic artery. These diagnostic methods were useful in designing the
optimal surgical strategy. The first case with a gluteal pulsating mass underwent exclusion of the persistent sciatic artery
including the aneurysm through a retroperitoneal approach with a combination of femorotibial bypass, while the second case
with thrombosed persistent sciatic artery only underwent femoropopliteal bypass. To recognize such a rare lesion, awareness
of the differential diagnosis is important, and to provide appropriate treatment, an accurate whole image including adequate
angiography, a CT scan, and magnetic resonance imaging is necessary. 相似文献
48.
Koichi Murata Yasuaki Nakagawa Takashi Suzuki Masahiko Kobayashi Seiya Kotani Takashi Nakamura 《Knee surgery, sports traumatology, arthroscopy》2007,15(10):1261-1263
Intraosseous ganglia of the glenoid are rare, and their etiology is unknown. This report describes a case of an intraosseous
ganglion about to cause fracture of the glenoid. The patient was a 61-year-old woman with a painful left shoulder with a limited
range of motion. Her symptoms did not improve after non-operative treatment. Arthroscopic examination showed a cartilage defect
and erosion in the posteroinferior portion of the glenoid, behind which computed tomography (CT) showed a cystic lesion of
the glenoid. There was no communication between the cyst and the joint space. The patient was treated by curettage and an
autogenous cancellous bone graft from the iliac crest. Two years after the operation, the patient was almost free from pain,
and CT showed good integration of the bone graft. 相似文献
49.
In 2002, psychiatrically disabled athletes joined an historic first open game of volleyball at the national sports games for the disabled. Compared to the competitive sports and Paralympic Games that physically and intellectually disabled athletes have participated in, activities for the psychiatrically disabled have not been well-organized. In this paper, we examine a number of problems that have arisen when the psychiatrically disabled joined competitive sports games. We identify two major characteristics of the psychiatrically disabled of particular relevance when organizing competitive sports activities. First, all psychiatrically disabled athletes need treatment of their individual diseases. For example, psychiatric symptoms fluctuate markedly over time, unlike physical or intellectual disabilities, whose symptoms are much more stable. Exacerbations of psychiatric illness are also likely to occur due to the stresses of competitiveness. Second, psychiatric disabilities are manifestations of disorders in the central nervous system, which makes the classification of psychiatric disabilities less straightforward than classification of the physically disabled. These two characteristics require special attention when organizing competitive athletic challenges that include the psychiatrically disabled. However, promoting sports activities that include the psychiatrically disabled would be expected to reduce the prejudice toward and subsequent social disadvantages experienced by psychiatric patients. Thus, with careful planning to successfully integrate psychiatrically disabled athletes, we expect increased promotion of such sports activities in the future. 相似文献
50.
Kenji Yoshimi Masatoshi Takeda Tsuyoshi Nishimura Takashi Kudo Yu Nakamura Kunitoshi Tada Nobuyoshi Iwata 《Brain research》1991,560(1-2):149-158
Changes in MAP2 and clathrin immunoreactivity were studied in gerbil hippocampus after transient cerebral ischemia. MAP2 immuno-reactivity decreased significantly by 1 h in the subiculum-CA1 and CA2 areas which correspond to reactive change, while no decrease was observed in CA1 until day 4. Before the initiation of delayed neuronal death, MAP2 immunoreactivity was not changed in CA1. On the other hand clathrin immunoreactivity increased in the pyramidal cell layer of CA1 by 3 h after ischemia and remained high for 2 days. Clathrin immunoreactivity in the pyramidal cell layer of CA1 diminished after delayed neuronal death. The transient change of clathrin was noted especially in CA1 in the period prior to delayed neuronal death. These results imply an abnormal change in clathrin turnover after ischemia, which may participate in the pathogenesis of delayed neuronal death. 相似文献