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Objective: The purpose of this study was to examine the relationship between
the emotional intelligence quotient and health-related quality of life using structural
equation modeling.Methods: A self-administered questionnaire survey was conducted among 1,911
mothers who visited the Health Center for an infant medical examination. A hypothetical
model was constructed using variables of the emotional intelligence quotient, social
support, coping, parenting stress, and perceived health competence.Result: There were a total of 1,104 valid responses (57.8%). Significant
standardized estimates were obtained, confirming the goodness of fit issues with the
model. The emotional intelligence quotient had a strong impact on physical and
psychological quality of life, and showed the greatest association with coping. This study
differed from previous studies in that, due to the inclusion of social support and
explanatory variables in coping, an increase in coping strategies was more highly
associated with emotional intelligence quotient levels than with social support.Conclusion: An enhanced emotional intelligence quotient should be considered
a primary objective to promote the health of mothers with infant children. 相似文献
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Incidence of gastric adenocarcinoma among lesions diagnosed as low‐grade adenoma/dysplasia on endoscopic biopsy: A multicenter,prospective, observational study 下载免费PDF全文
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Haruo Makuuchi Akira Furuse Masahiro Endo Haruo Nakamura Hiroyuki Daida Mikio Watanabe Yasuo Ohashi Yasuyuki Hosoda Saichi Hosoda Hiroshi Yamaguchi Hisataka Yasui 《Circulation journal》2005,69(6):636-643
BACKGROUND: Although the anti-atherosclerotic effects of HMG-CoA reductase inhibitors are well known, their specific effect on saphenous vein grafts after coronary artery bypass graft (CABG) operation is not well documented and has not been studied in Japan, so the aim of the present prospective randomized controlled study involving 27 Japanese institutions was to investigate the effects of pravastatin on the progression of atherosclerosis in such grafts and native coronary arteries after CABG. METHODS AND RESULTS: A total of 303 patients who had undergone CABG were randomly assigned to either the pravastatin group (n =168) or the control group (n = 167). Paired coronary angiograms were obtained at baseline and at the end of 5-year follow-up in 182 (60%) patients. The low-density lipoprotein cholesterol concentration significantly decreased in the pravastatin group from 141.4 mg/dl to 113.7 mg/dl (-19.6%), compared with 141.1 mg/dl to 133.7 mg/dl (-5.2%) in the control group (p < 0.001). Although there was no significant difference in the quantitative coronary angiography measurements between the 2 groups, the global change score indicated a significant pravastatin-mediated reduction in plaque progression (p < 0.01). CONCLUSIONS: Pravastatin can potentially reduce atherosclerotic progression in both the bypass graft and native coronary arteries of patients after CABG. 相似文献
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Endothelin-1(1-31) levels are increased in atherosclerotic lesions of the thoracic aorta of hypercholesterolemic hamsters 总被引:2,自引:0,他引:2
Mawatari K Kakui S Harada N Ohnishi T Niwa Y Okada K Takahashi A Izumi K Nakaya Y 《Atherosclerosis》2004,175(2):203-212
OBJECTIVE: The novel vaso-constricting 31-amino acid-length endothelin-1 [ET-1(1-31)] is selectively produced by human mast cell chymase via its action on big ET-1. However, the pathological role of ET-1(1-31) in atherosclerosis remains unclear. The aim of this study was to clarify vasoconstrictive response and expression of ET-1(1-31) in atherosclerotic aorta. METHODS AND RESULTS: Syrian golden hamster, was used for preparing the atherosclerotic models by the administration of a high cholesterol diet (HC), treatment with the nitric oxide synthase inhibitor (Nomega-nitro-L-arginine methylester, L-NAME) alone, or both (HC and L-NAME) for 40 weeks. Early atherosclerosis was observed in the case of HC or L-NAME alone treatments respectively and severe atherosclerosis was observed in the case of combined HC and L-NAME treatment. Vasoconstriction induced by ET-1(1-31) was not altered by the atherosclerotic changes, but the expression pattern of ET-1(1-31) was different at each stage of the atherosclerotic aorta. ET-1(1-31) was observed rarely in normal aortas or in early atherosclerotic lesions, but ET-1(1-31) expression was dramatically increased in aortic neointima and adventitia in a state of atherosclerosis with severe inflammation. CONCLUSION: ET-1(1-31) might play in a role of promoting atherosclerosis, and especially be involved in inflammatory mediation during the progression of atherosclerosis. 相似文献