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151.
Hiroi M Takahashi N Harada T Kawamori F Iida N Kanda T Sugiyama K Ohashi N Hara-Kudo Y Masuda T 《Japanese journal of infectious diseases》2012,65(3):198-202
The serotype, Shiga toxin (Stx) type, and antimicrobial resistance patterns of 138 Stx-producing Escherichia coli (STEC) strains isolated from humans between 2003 and 2007 in Shizuoka Prefecture, Japan were characterized. The predominant O serogroups of the STEC isolates were O157, O26, and O111. Antimicrobial susceptibility testing of the STEC isolates showed that 31 of the 138 isolates (22.5%) were resistant to antibiotics. Compared to the results reported in the previous studies, a higher rate of STEC O157 isolates were susceptible to all the antimicrobial agents used in this study. However, antimicrobial susceptibility data from this study showed that antimicrobial resistance patterns have increased by 6 compared to the survey performed by Masuda et al. between 1987 and 2002 (Jpn. J. Food Microbiol., 21, 44-51, 2004). This indicates that STEC isolates have evolved to show a variety of antimicrobial resistance patterns. It is important to consider the population of isolates showing decreased susceptibility to clinically relevant drugs such as ciprofloxacin (CPFX) and fosfomycin (FOM). All the 3 STEC isolates resistant to nalidixic acid showed low susceptibility to CPFX (MIC, 0.25-0.5 μg/ml). In addition, a decreased susceptibility to FOM was clearly observed in the E. coli O26 isolates. Our findings also showed that 1 STEC O26 strain could possibly be a chromosomal AmpC β-lactamase hyperproducer. These results suggest that antimicrobial therapy may be less effective in patients with non-O157 STEC infections than in those with STEC O157 infections. 相似文献
152.
Kawada H Dida GO Ohashi K Sonye G Njenga SM Mwandawiro C Minakawa N Takagi M 《Japanese journal of infectious diseases》2012,65(3):243-246
We evaluated the effectiveness of installing the Olyset? Net on the ceiling in preventing the invasion of malaria vectors. This study was conducted in houses in western Kenya. The number of resting mosquitoes inside the houses reduced when the ceiling and eaves of the houses were covered with the net. The mosquito densities remained low for 9 months, until the nets were removed. 相似文献
153.
Miho Ota Masanori Ishikawa Noriko Sato Hiroaki Hori Daimei Sasayama Kotaro Hattori Toshiya Teraishi Takamasa Noda Satoko Obu Yasuhiro Nakata Teruhiko Higuchi Hiroshi Kunugi 《Journal of psychiatric research》2013
Background
Although schizophrenia and major depressive disorder (MDD) differ on a variety of neuroanatomical measures, a diagnostic tool to discriminate these disorders has not yet been established. We tried to identify structural changes of the brain that best discriminate between schizophrenia and MDD on the basis of gray matter volume, ventricle volume, and diffusion tensor imaging (DTI).Method
The first exploration sample consisted of 25 female patients with schizophrenia and 25 females with MDD. Regional brain volumes and fractional anisotropy (FA) values were entered into a discriminant analysis. The second validation sample consisted of 18 female schizophrenia and 16 female MDD patients.Results
The stepwise discriminant analysis resulted in correct classification rates of 0.80 in the schizophrenic group and 0.76 in MDD. In the second validation sample, the obtained model yielded correct classification rates of 0.72 in the schizophrenia group and 0.88 in the MDD group.Conclusion
Our results suggest that schizophrenia and MDD have differential structural changes in the examined brain regions and that the obtained discriminant score may be useful to discriminate the two disorders. 相似文献154.
Life review with music activities such as singing and listening to clients’ meaningful or memorable songs is a commonly practiced technique in various clinical settings. In the current paper, two case studies of life review with two Japanese elderly women with dementia were presented. We used a theoretical framework called “Musical Life Review” model (Sato, 2011) to analyze the functions of clients’ meaningful or memorable songs used during life review sessions. Furthermore, we determined spiritual needs displayed by clients with Murata's theoretical model (Murata, 2003), which is intended to clarify the structure of spiritual pain. Clinical values and functional meanings of musical life review for people with dementia were also discussed. 相似文献
155.
A comparison of error detection rates between the reading aloud method and the double data entry method 总被引:1,自引:0,他引:1
Kawado M Hinotsu S Matsuyama Y Yamaguchi T Hashimoto S Ohashi Y 《Controlled clinical trials》2003,24(5):560-569
Data entry and its verification are important steps in the process of data management in clinical studies. In Japan, a kind of visual comparison called the reading aloud (RA) method is often used as an alternative to or in addition to the double data entry (DDE) method. In a typical RA method, one operator reads previously keyed data aloud while looking at a printed sheet or computer screen, and another operator compares the voice with the corresponding data recorded on case report forms (CRFs) to confirm whether the data are the same. We compared the efficiency of the RA method with that of the DDE method in the data management system of the Japanese Registry of Renal Transplantation. Efficiency was evaluated in terms of error detection rate and expended time. Five hundred sixty CRFs were randomly allocated to two operators for single data entry. Two types of DDE and RA methods were performed. Single data entry errors were detected in 358 of 104,720 fields (per-field error rate=0.34%). Error detection rates were 88.3% for the DDE method performed by a different operator, 69.0% for the DDE method performed by the same operator, 59.5% for the RA method performed by a different operator, and 39.9% for the RA method performed by the same operator. The differences in these rates were significant (p<0.001) between the two verification methods as well as between the types of operator (same or different). The total expended times were 74.8 hours for the DDE method and 57.9 hours for the RA method. These results suggest that in detecting errors of single data entry, the RA method is inferior to the DDE method, while its time cost is lower. 相似文献
156.
Erectile function status is highly associated with prostate‐specific antigen bounce in localized prostate cancer patients treated with permanent prostate brachytherapy
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157.
158.
Toshihiro Yasui Tatsuya Suzuki Fujio Hara Shunsuke Watanabe Naoko Uga Atsuki Naoe Tetsushi Yoshikawa Tetsuya Ito Yoko Nakajima Hiroki Miura Atsushi Sugioka Yutaro Kato Takamasa Tokoro Yoshinao Tanahashi Mureo Kasahara Akinari Fukuda Hiroki Kurahashi 《Pediatric transplantation》2016,20(5):707-710
MSUD is an autosomal recessive condition characterized by a deficiency in the enzyme, BCKDH, which catalyzes the breakdown of BCAAs. If left untreated, MSUD can result in mental retardation, central nervous system disorders, and even death. Most patients with MSUD are treated with a restricted protein diet and milk from which BCAAs have been removed. LT has been shown effective in patients with MSUD. This report describes the case of a 15‐month‐old boy who received a liver graft from his mother. Transplantation was successful, and the patient was then able to ingest a normal diet. Despite episodes of acute rejection, chylous ascites, and high fever (40 °C), he has shown no evidence of MSUD recurrence. These findings indicate that patients with MSUD can be successfully treated by LDLT, even when the donor is a heterozygous carrier of a mutated BCKDH gene. 相似文献
159.
Atsushi Kasamatsu Atsushi Ohashi Shoji Tsuji Hidetaka Okada Hideharu Kanzaki Kazunari Kaneko 《Clinical and experimental nephrology》2016,20(5):764-769