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101.
Takahiro Matsui Akio Iwasa Masafumi Mimura Seiji Taniguchi Takao Sudo Yutaka Uchida Junichi Kikuta Hidetomo Morizono Rie Horii Yuichi Motoyama Eiichi Morii Shinji Ohno Yasujiro Kiyota Masaru Ishii 《Cancer science》2022,113(8):2916
Histopathological diagnosis is the ultimate method of attaining the final diagnosis; however, the observation range is limited to the two‐dimensional plane, and it requires thin slicing of the tissue, which limits diagnostic information. To seek solutions for these problems, we proposed a novel imaging‐based histopathological examination. We used the multiphoton excitation microscopy (MPM) technique to establish a method for visualizing unfixed/unstained human breast tissues. Under near‐infrared ray excitation, fresh human breast tissues emitted fluorescent signals with three major peaks, which enabled visualizing the breast tissue morphology without any fixation or dye staining. Our study using human breast tissue samples from 32 patients indicated that experienced pathologists can estimate normal or cancerous lesions using only these MPM images with a kappa coefficient of 1.0. Moreover, we developed an image classification algorithm with artificial intelligence that enabled us to automatically define cancer cells in small areas with a high sensitivity of ≥0.942. Taken together, label‐free MPM imaging is a promising method for the real‐time automatic diagnosis of breast cancer. 相似文献
102.
Kamio M Oki T Inomoto Y Tsuji T Yoshinaga M Douchi T 《The journal of obstetrics and gynaecology research》2007,33(1):87-90
We encountered a 10-year-old prepubertal girl with a normal ovary and oviduct torsion. Hemorrhagic infarction of the ovary and oviduct occurred, and these structures were laparoscopically removed. Torsion of the normal ovary and oviduct in a prepubertal girl is discussed. 相似文献
103.
Isolated adenomyotic cyst associated with severe dysmenorrhea 总被引:1,自引:0,他引:1
Kamio M Taguchi S Oki T Tsuji T Iwamoto I Yoshinaga M Douchi T 《The journal of obstetrics and gynaecology research》2007,33(3):388-391
A case of a 23-year-old, nulliparous female with a very rare isolated adenomyotic cyst inducing severe dysmenorrhea was seen. Transvaginal ultrasonographic tomography and magnetic resonance imaging (MRI) showed a 3 x 3-cm cystic mass within the left anterior wall of the uterine corpus. The cystic space was filled with hyperintense fluid on T1-weighted images, which was surrounded by hypointense tissue beside the right uterine corpus on T2-weighted images. The case was preliminarily diagnosed using MRI as having cavitated rudimentary uterine horn. However, hysterosalpingography excluded the possibility of uterine anomaly. A hemorrhagic adenomyotic cyst measuring 3 cm within the left anterior wall of the uterine corpus was surgically removed. There was no evidence of diffuse adenomyosis uteri. Dysmenorrhea completely disappeared postoperatively. 相似文献
104.
Gasidit Panomsuwan Chadapat Hussakan Napat Kaewtrakulchai Ratchatee Techapiesancharoenkij Ai Serizawa Takahiro Ishizaki Apiluck Eiad-ua 《RSC advances》2022,12(27):17481
A massive amount of animal biomass is generated daily from livestock farms, agriculture, and food industries, causing environmental and ecological problems. The conversion of animal biomass into value-added products has recently gained considerable interest in materials science research. Herein, horse manure (HM) was utilized as a precursor for synthesizing nitrogen-doped carbons (NCs) via hydrothermal ammonia treatment and the post pyrolysis process. The ammonia concentration varied between 0.5, 1.0, and 1.5 M in the hydrothermal process. From the comprehensive characterization results, horse manure-derived nitrogen-doped carbons (HMNCs) exhibited an amorphous phase and a hierarchical nanoporous structure. The specific surface area decreased from 170.1 to 66.6 m2 g−1 as the ammonia concentration increased due to micropore deterioration. The nitrogen content was 0.90 atom% even with no ammonia treatment, indicating self-nitrogen doping. With hydrothermal ammonia treatment, the nitrogen content slightly enhanced up to 1.54 atom%. The electrocatalytic activity for the oxygen reduction reaction (ORR) of HMNCs in an alkaline solution was found to be related to nitrogen doping content and porous structure. The ORR activity of HMNCs mainly proceeded via a combination of two- and four-electron pathways. Although the ORR activity of HMNCs was still not satisfactory and comparable to that of a commercial Pt/carbon catalyst, it showed better long-term durability. The results obtained in this work provide the potential utilization of HM as a precursor for ORR catalysts and other related applications.This work shows the potential utilization of horse manure as a precursor for synthesizing nitrogen-doped carbons for electrocatalytic oxygen reduction reaction. 相似文献
105.
Masami Goto Osamu Abe Akifumi Hagiwara Shohei Fujita Koji Kamagata Masaaki Hori Shigeki Aoki Takahiro Osada Seiki Konishi Yoshitaka Masutani Hajime Sakamoto Yasuaki Sakano Shinsuke Kyogoku Hiroyuki Daida 《Magnetic resonance in medical sciences》2022,21(1):41
Surface-based morphometry (SBM) is extremely useful for estimating the indices of cortical morphology, such as volume, thickness, area, and gyrification, whereas voxel-based morphometry (VBM) is a typical method of gray matter (GM) volumetry that includes cortex measurement. In cases where SBM is used to estimate cortical morphology, it remains controversial as to whether VBM should be used in addition to estimate GM volume. Therefore, this review has two main goals. First, we summarize the differences between the two methods regarding preprocessing, statistical analysis, and reliability. Second, we review studies that estimate cortical morphological changes using VBM and/or SBM and discuss whether using VBM in conjunction with SBM produces additional values. We found cases in which detection of morphological change in either VBM or SBM was superior, and others that showed equivalent performance between the two methods. Therefore, we concluded that using VBM and SBM together can help researchers and clinicians obtain a better understanding of normal neurobiological processes of the brain. Moreover, the use of both methods may improve the accuracy of the detection of morphological changes when comparing the data of patients and controls.In addition, we introduce two other recent methods as future directions for estimating cortical morphological changes: a multi-modal parcellation method using structural and functional images, and a synthetic segmentation method using multi-contrast images (such as T1- and proton density-weighted images). 相似文献
106.
Mari Maeda-Yamamoto Osamu Honmou Masanori Sasaki Akane Haseda Hiroyo Kagami-Katsuyama Toshihiko Shoji Ai Namioka Takahiro Namioka Hirotoshi Magota Shinichi Oka Yuko Kataoka-Sasaki Ryou Ukai Mitsuhiro Takemura Jun Nishihira 《Nutrients》2022,14(12)
The purple-flesh potato (Solanum tuberosum L.) cultivar “Shadow Queen” (SQ) naturally contains anthocyanins. This randomized, double-blind, placebo-controlled study determines whether ingesting purple potatoes increases the number of mesenchymal stem cells (MSC) and improves stress response, a minor health complaint in healthy adults (registration number: UMIN000038876). A total of 15 healthy subjects (ages: 50–70 years) with minor health complaints were randomly assigned to one of two groups. For 8 weeks, the placebo group received placebo potatoes cv. “Haruka” and the test group received test potato cv. SQ containing 45 mg anthocyanin. The MSC count and several stress responses were analyzed at weeks 0 and 8 of the intake periods. The ingestion of a SQ potato did not affect the MSC count but markedly improved psychological stress response, irritability, and depression as minor health complaints compared with “Haruka”. No adverse effects were noted. Hence, an 8-week intake of SQ could improve stress responses. 相似文献
107.
Tomoki Kuge Kiyoharu Fukushima Yuki Matsumoto Haruko Saito Yuko Abe Eri Akiba Kako Haduki Tadayoshi Nitta Akira Kawano Michio Tanaka Yumi Hattori Takahiro Kawasaki Takanori Matsuki Takayuki Shiroyama Daisuke Motooka Kazuyuki Tsujino Keisuke Miki Masahide Mori Seigo Kitada Shota Nakamura Tetsuya Iida Atsushi Kumanogoh Hiroshi Kida 《Emerging infectious diseases》2022,28(7):1437
Unidentified Mycobacterium species are sometimes detected in respiratory specimens. We identified a novel Tsukamurella species (Tsukamurella sp. TY48, RIMD 2001001, CIP 111916T), Tsukamurella toyonakaense, from a patient given a misdiagnosis of nontuberculous mycobacterial pulmonary disease caused by unidentified mycobacteria. Genomic identification of this Tsukamurella species helped clarify its clinical characteristics and epidemiology. 相似文献
108.
Hiroyuki Fujiwara Akihiro Shimoda Yoshiki Ishikawa Akiyo Taneichi Mai Ohashi Yoshifumi Takahashi Takahiro Koyanagi Hiroyuki Morisawa Suzuyo Takahashi Naoto Sato Shizuo Machida Yuji Takei Yasushi Saga Mitsuaki Suzuki 《Archives of Public Health》2015,73(1)
Background
In Japan, the cervical cancer screening rate is extremely low. Towards improving the cervical cancer screening rate, encouraging eligible people to make an informed choice, which is a decision-making process that relies on beliefs informed by adequate information about the possible benefits and risks of screening, has attracted increased attention in the public health domain. However, there is concern that providing information on possible risks of screening might prevent deter from participating.Methods
In total, 1,912 women aged 20–39 years who had not participated in screening in the fiscal year were selected from a Japanese urban community setting. Participants were randomly divided into 3 groups. Group A received a printed reminder with information about the possible benefits of screening, group B received a printed reminder with information about possible benefits and risks, and group C received a printed reminder with simple information only (control group).Results
Out of 1,912 participants, 169 (8.8%) participated in cervical cancer screening. In the intervention groups, 137 (10.9%) participated in cervical cancer screening, compared to only 32 (4.9%) of the control group (p < 0.001). In addition, logistic regression analysis revealed that there was no significant difference in screening rate between group A and group B (p = 0.372).Conclusions
Providing information on the possible risks of screening may not prevent people from taking part in cervical cancer screening among a Japanese non-adherent population. 相似文献109.
Shingo Machida Reo Kato Kaishi Hasegawa Takahiro Gotoh Ken-ichi Katsumata Atsuo Yasumori 《Materials》2022,15(15)
Photoreduction of Cu2+ ions to Cu metal by titanium(IV) oxide (TiO2) was conducted in the presence of a silica–surfactant hybrid under sulfuric acid conditions. After irradiation, a dark-red color, reflections due to Cu metal in the X-ray diffraction pattern, and peaks due to Cu 2p1/2 and 2p3/2 in the X-ray photoelectron spectrum indicated the precipitation of Cu metal in the product. In addition, an increase in the Brunauer–Emmett–Teller specific surface area from 36 and 45 m2/g for the silica–surfactant and TiO2, respectively, to 591 m2/g for the product, and a decrease in the intensity of the C-H stretching band in the Fourier–transform infra-red spectra implied the removal of surfactant during the reaction. These characteristics were never observed when TiO2 was used solely. Therefore, this study indicated that the photoreduction of Cu2+ ions to Cu metal by TiO2 was facilitated under the sulfuric acid medium, where the surfactants extracted from silica–surfactant hybrids by protons in the acidic condition were successfully photo-oxidized by TiO2. Thus, this study presents a new application of the conversion of a silica–surfactant hybrid into mesoporous silicas. 相似文献
110.
Hidenori Kanazawa Kenichi Utano Shigeyoshi Kijima Takahiro Sasaki Yasuyuki Miyakura Hisanaga Horie Yoshikazu Nakamura Hideharu Sugimoto 《Japanese journal of radiology》2014,32(5):274-281