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排序方式: 共有10000条查询结果,搜索用时 546 毫秒
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Yamasaki N Matsumoto K Ohta Y Nishida T Adachi A Nakagawa K Kawakami K 《Kyobu geka. The Japanese journal of thoracic surgery》2000,53(9):791-794
We have experienced thoracoscopic surgery for benign solitary fibrous tumor of the parietal pleura. A 46-year-old woman was admitted to our hospital because of chest abnormal shadow. Under thoracoscopy the tumor that was connected to the parietal pleura with a wide pedicle was completely resected with combined parietal resection of the pleura. Pathological diagnosis was a benign solitary fibrous tumor developed from the connective tissues under the parietal pleura. Thoracoscopic surgery is well indicated for a solitary fibrous tumor and wide excision of the tumor with combined resection of the pleura is important to prevent a local recurrence. 相似文献
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Carlo Palmieri Rob C. Stein Xinxue Liu Emma Hudson Hanna Nicholas Hironobu Sasano Fouzia Guestini Chris Holcombe Sophie Barrett Laura Kenny Sadie Reed Adrian Lim Larry Hayward Sacha Howell R. Charles Coombes On behalf of the IRIS
trial participants 《Breast cancer research and treatment》2017,162(2):343-352
Purpose
High mammographic breast density (BD) is a strong risk factor of breast cancer; however, little is known in women under 40 years of age. Recently, dual-energy X-ray Absorptiometry (DXA) has been developed as a low-dose method to measure BD in young populations. Thus, our aims were to describe BD in relation to risk factors in Chilean women under 40 years old and to explore the equivalence of DXA to mammography for the measurement of BD.Methods
We selected 192 premenopausal Chilean female participants of the DERCAM study for whom we have anthropometric, sociodemographic, and gyneco-obstetric data. The subjects received both digital mammograms (Hologic) and breast DXA scans (GE iDXA). Mammographic BD was estimated using a fully automated commercial method (VOLPARA®) and BI-RADS. Breast DXA scans were performed using a standardized protocol and the % fibroglandular volume (%FGV) was estimated considering a two-compartment model of adipose and fibroglandular tissue.Results
The mean age was 37 years (SD = 6.5) and 31.6% of the subjects were obese. The median %FGV and absolute FGV (AFGV) measured by DXA were 9% and 198.1 cm3 and for VOLPARA®, 8.6% and 58.0 cm3, respectively. The precision for %FGV after reposition was 2.8%. The correlation coefficients for %FGV, AFGV, and breast volume between DXA and mammography were over 0.7. Age and body mass index (BMI) were inversely associated with %FGV, and BMI was positively related to AFGV as estimated with DXA or mammography. We did not observe an association with gyneco-obstetric characteristics, education, and %FGV and AFGV; smoking was only associated with AFGV as measured by VOLPARA®.Conclusions
DXA is an alternative method to measure volumetric BD; thus, it could be used to continuously monitor BD in adult women in follow-up studies or to assess BD in young women.999.
Yonemori K Katsumata N Kaneko M Uno H Matsumoto K Kouno T Shimizu C Ando M Takeuchi M Fujiwara Y 《Breast cancer research and treatment》2007,103(3):313-318
Summary
Purpose: The aim of this study was to identify the predictors of the response to doxorubicin plus cyclophosphamide in patients with
recurrent breast cancer (RBC) previously treated with anthracycline-containing regimens in a neoadjuvant or adjuvant setting.
Method: Between December 1993 and October 2005, 664 patients had received combined doxorubicin plus cyclophosphamide chemotherapy
(doxorubicin, 40 mg/m2, iv on day 1; cyclophosphamide, 500 mg/m2, iv on day 1, every 21 days) for RBC at our institution. In this study, we retrospectively analyzed the efficacy of doxorubicin
plus cyclophosphamide in 99 of these 664 RBC patients who had also previously been administered an anthracycline-based chemotherapy
in a neoadjuvant or adjuvant setting.
Results: The median cumulative dose of the previously administered anthracycline was 156 mg/m2. The median disease-free interval (DFI) and median anthracycline-free interval were 33.8 and 43.7 months, respectively. The
overall response rate to doxorubicin plus cyclophosphamide therapy was 38.4% (95% CI; range, 28.8–48.0%). The median time
to progression and overall survival were 6.2 and 17.5 months, respectively. The results of a multivariate logistic regression
analysis revealed a significant association of the response to doxorubicin plus cyclophosphamide therapy with the DFI (P = 0.02); human epidermal receptor type 2 (HER2) status also tended to affect the response rate, however the association was
not statistically significant (P = 0.06).
Conclusion: DFI and HER2 status may be associated with the response to repeat utilization of anthracycline-containing regimens in RBC
patients also treated previously with anthracycline-containing chemotherapeutic regimens in a neoadjuvant or adjuvant setting. 相似文献
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