全文获取类型
收费全文 | 817篇 |
免费 | 26篇 |
国内免费 | 2篇 |
专业分类
耳鼻咽喉 | 3篇 |
儿科学 | 50篇 |
妇产科学 | 4篇 |
基础医学 | 70篇 |
口腔科学 | 19篇 |
临床医学 | 44篇 |
内科学 | 90篇 |
皮肤病学 | 37篇 |
神经病学 | 11篇 |
特种医学 | 64篇 |
外科学 | 92篇 |
综合类 | 280篇 |
预防医学 | 28篇 |
眼科学 | 8篇 |
药学 | 17篇 |
1篇 | |
肿瘤学 | 27篇 |
出版年
2022年 | 11篇 |
2021年 | 11篇 |
2020年 | 9篇 |
2019年 | 8篇 |
2018年 | 10篇 |
2017年 | 4篇 |
2016年 | 6篇 |
2015年 | 26篇 |
2014年 | 29篇 |
2013年 | 24篇 |
2012年 | 28篇 |
2011年 | 24篇 |
2010年 | 67篇 |
2009年 | 46篇 |
2008年 | 49篇 |
2007年 | 44篇 |
2006年 | 48篇 |
2005年 | 28篇 |
2004年 | 50篇 |
2003年 | 17篇 |
2002年 | 24篇 |
2001年 | 28篇 |
2000年 | 20篇 |
1999年 | 20篇 |
1998年 | 26篇 |
1997年 | 30篇 |
1996年 | 28篇 |
1995年 | 17篇 |
1994年 | 21篇 |
1993年 | 8篇 |
1992年 | 7篇 |
1991年 | 2篇 |
1989年 | 6篇 |
1988年 | 6篇 |
1987年 | 5篇 |
1986年 | 7篇 |
1985年 | 5篇 |
1984年 | 3篇 |
1982年 | 6篇 |
1981年 | 6篇 |
1980年 | 3篇 |
1979年 | 6篇 |
1978年 | 7篇 |
1977年 | 2篇 |
1976年 | 5篇 |
1974年 | 1篇 |
1973年 | 1篇 |
1972年 | 1篇 |
1955年 | 1篇 |
1953年 | 1篇 |
排序方式: 共有845条查询结果,搜索用时 15 毫秒
51.
52.
ŞAKIR ALTUNBAŞAK EMRE ALHAN VILDAN BAYTOK NECMI AKSARAY BILGIN YÜKSEL NESLIHAN ÖNENLI 《Pediatrics international》1994,36(5):480-484
Between May 1988 and November 1992 the data from 52 patients with tuberculous meningitis (TBM) were noted down for their symptoms and signs, BCG vaccines, PPD tests; clinical, laboratory, radiologic and microbiologic findings. These data were discussed by means of literature knowledge. Cranial computed tomography (CT) demonstrated hydrocephalus (HC) in 98% of the patients. There was a statistically significant difference among the clinical stages on admission in respect to prognosis (P < 0.05). In addition, there was also a significant relationship between prognosis and HC (P < 0.05). However, we did not find any significant relationship between parenchymal involvement, basilar meningitis and prognosis (P > 0.05). 相似文献
53.
54.
55.
Background
BCG vaccine is considered to have immunoprophylactic potential in leprosy. However controversy exists about the extent of prophylaxis it provides. In view of this, a study was undertaken to see the evolution of disease in established cases of leprosy who were already vaccinated with BCG and to compare it with the cases of leprosy who were not vaccinated with BCG.Methods
114 newly diagnosed cases of leprosy were studied. Patients were divided into two groups-BCG vaccinated and non-vaccinated. Clinical diagnosis of leprosy was confirmed by bacteriological and histopathological studies in each case. All patients were given standard anti leprosy treatment and were evaluated monthly for a minimum period of one year.Results
All the cases were males in the age group of 20 to 50 years. 25.4% of cases had received BCG vaccine and 74.6% were not vaccinated for the same. No significant difference was observed in the incidence of different types of leprosy in vaccinated and non-vaccinated groups. 25.9% cases in non-vaccinated group developed lepra reaction as compared to 13.8% in vaccinated group. The incidence of deformities and disabilities in vaccinated group was only 10.3% as against 18.8% in non-vaccinated group. The rate of bacillary clearance appeared faster in vaccinated group.Conclusions
Although there is no significant difference in the pattern of different types of leprosy in BCG vaccinated and non-vaccinated cases, there is reduction in the incidence of reactions as well as deformities and disabilities in BCG vaccinated cases as compared to non-vaccinated cases.Key Words: BCG Vaccine, Leprosy 相似文献56.
Background
India accounts for approximately 10 million orthopaedically handicapped children and adults with limb deformity. Ilizarov ring fixator could treat most of these deformities.Methods
Twenty cases of deformities of lower limb managed with Ilizarov technique during period between March 2001 and February 2003 were studied.Results
55% were in the age group of 11-30 years. Out of the 20 cases studied, 6 were congenital talipes equino varus, 8 were fixed flexion deformity of knee, 4 were equines deformity of the ankle and 2 were malunited fracture shaft of tibia.4 patients who had recurrence were operated for fixed flexion deformity of the knee. The main complication encountered was pin tract infection, which was seen in 15(75%) cases. In 16(80%) cases, the results were excellent with no recurrence of deformity and patients were able to walk independently. In 4 (20%) cases, recurrence was mild to moderate (10 to 20) but all of them were able to ambulate idependently and carry out their routine activities.Conclusion
Ilizarov ring fixator is a superior compared to conventional methods for correction of deformities of lower limb.Key Words: Ilizarov method, Ligamentotaxis, Distraction 相似文献57.
Amann M Subudhi AW Walker J Eisenman P Shultz B Foster C 《Medicine and science in sports and exercise》2004,36(10):1716-1722
PURPOSE: To identify a valid and reliable method to determine 40-km time trial (40K) performance in a laboratory setting. METHODS: Part 1: Ventilatory threshold (VT) and 40K performance were determined on two occasions (February/September) using two subsets of cyclists (N = 15 each; VO(2max) 67.6 +/- 4.2/71.5 +/- 3.0 mL x kg(-1) x min(-1)) to determine the predictive validity of VT assessments. Variables of interest were power output at VT, peak power output (MaxVT(w)), and average power output during 40K (40K(avgwatts)). For VT determination we used: breakpoint of VE/VO2; breakpoint of VE/VCO2; V-slope; RER = 1; and RER = 0.95. In part 2, test-retest reliability of VT and MaxVT(w) were examined in 20 subjects (VO(2max) 64.8 +/- 8.0 mL x kg(-1) x min(-1)) on two occasions, separated by 48 h. RESULTS: Regression analyses between power outputs at VTs and 40K(avgwatts) showed significant predictive validity for (February/September): V-slope (r = 0.79/0.84; SEE 155/13.3W), VE/VO2 (r = 0.80/0.81; SEE 15.2/14.2W), RER0.95 (r = 0.73/0.58; SEE 17.4/21.2W), RER1 (r = 0.75/0.74; SEE 16.8/16.7W), and MaxVT(w) (r = 0.81/0.73; SEE 15.0/17.1W). Paired t-tests between power outputs at VTs and the 40K(avgwatts) indicated that mean power outputs at VE/O2 (261 +/- 29W; P = 0.33) and RER0.95 (274 +/- 55W; P = 0.93) in February and VE/VO2 (274 +/- 37W; P = 0.79) in September were not significantly different from the respective 40K(avgwatts) (277 +/- 30W/281 +/- 30W). Test-retest reliability analysis yielded the following intraclass correlation and relative test-retest errors: V-slope: 0.98, 2.6%; VE/VO2: 0.95, 5.3%; RER0.95: 0.87, 9.8%; RER1: 0.94, 5.7%; VE/VCO2: 0.87, 12.1%; MaxVT(w): 0.98, 2.6%. CONCLUSION: The high test-retest reliability and consistent ability to accurately predict athletes' 40K(avgwatts) across a competitive season indicated that VE/VO2 was superior to the other evaluated methods. 相似文献
58.
Subudhi AW Jacobs KA Hagobian TA Fattor JA Fulco CS Muza SR Rock PB Hoffman AR Cymerman A Friedlander AL 《Aviation, space, and environmental medicine》2004,75(10):881-888
INTRODUCTION: Hypobaric hypoxia and heightened metabolic rate increase free radical production. PURPOSE: We tested the hypothesis that antioxidant supplementation would reduce oxidative stress associated with increased energy expenditure (negative energy balance) at high altitude (HA 4300 m). METHODS: For 12 d at sea level (SL), 18 active men were fed a weight-stabilizing diet. Testing included fasting blood and 24-h urine samples to assess antioxidant status [plasma alpha-tocopherol, beta-carotene, lipid hydroperoxides (LPO), and urinary 8-hydroxydeoxyguanosine (8-OHdG)] and a prolonged submaximal (55% Vo2peak) oxidative stress index test (OSI) to evaluate exercise-induced oxidative stress (plasma LPO, whole blood reduced and oxidized glutathione, glutathione peroxidase, and urinary 8-OHdG). Subjects were then matched and randomly assigned to either a placebo or antioxidant supplement group for a double-blinded trial. Supplementation (20,000 IU of beta-carotene, 400 IU alpha-tocopherol acetate, 500 mg ascorbic acid, 100 microg selenium, and 30 mg zinc, or placebo) was begun 3 wk prior to and throughout a 14-d HA intervention. At HA, subjects' daily energy intake and expenditure were adjusted to achieve a caloric deficit of approximately 1400 kcal. Fasting blood and 24-h urine samples were collected throughout HA and the OSI test was repeated on HA day 1 and day 13. RESULTS: Resting LPO concentrations increased and urinary 8-OHdG concentrations decreased over HA with no effect of supplementation. Prolonged submaximal exercise was not associated with increased concentrations of oxidative stress markers at SL or HA. CONCLUSIONS: Antioxidant supplementation did not significantly affect markers of oxidative stress associated with increased energy expenditure at HA. 相似文献
59.
S Ashraff AK Gupta S Chaudhury S Sudarsanan MSVK Raju SK Salujha K Srivastava 《Medical Journal Armed Forces India》2004,60(2):109-112
A total of 50 patients undergoing cancer treatment at Malignant Disease Treatment Centre were included in the present study aimed at evaluating the psychological status of cancer patients. All patients filled a specially designed proforma and the following psychological questionnaires : General Health Questionnaire, Carroll Rating Scale for Depression, State-Trait Anxiety Inventory, PGI General Well-being Scale and Quality of Life Scale. Analysis of the results showed that 22 (44%) of the cancer patients had psychiatric disorders and this number had reduced to 12 (24%) after therapy. The difference was statistically significant. Psychiatric treatment also resulted in a statistically significant reduction in level of depression as measured by Carroll Rating Scale for depression. Short term psychiatric treatment was found to be very useful in treating psychiatric morbidity and depression in cancer patients.Key Words: Cancer, Depression, Psychiatric morbidity 相似文献
60.
Background: An outbreak of food poisoning in a military establishment mess was investigated and remedial measures suggested. 相似文献