全文获取类型
收费全文 | 77篇 |
免费 | 9篇 |
国内免费 | 1篇 |
专业分类
儿科学 | 2篇 |
妇产科学 | 1篇 |
基础医学 | 6篇 |
口腔科学 | 1篇 |
临床医学 | 10篇 |
内科学 | 23篇 |
皮肤病学 | 2篇 |
神经病学 | 4篇 |
特种医学 | 11篇 |
外科学 | 1篇 |
综合类 | 9篇 |
预防医学 | 7篇 |
眼科学 | 1篇 |
药学 | 4篇 |
肿瘤学 | 5篇 |
出版年
2021年 | 1篇 |
2020年 | 2篇 |
2018年 | 4篇 |
2017年 | 2篇 |
2016年 | 2篇 |
2015年 | 4篇 |
2014年 | 6篇 |
2013年 | 6篇 |
2012年 | 3篇 |
2011年 | 1篇 |
2010年 | 4篇 |
2009年 | 5篇 |
2008年 | 2篇 |
2007年 | 1篇 |
2006年 | 1篇 |
2005年 | 1篇 |
2004年 | 1篇 |
2003年 | 3篇 |
2001年 | 1篇 |
1999年 | 3篇 |
1998年 | 2篇 |
1997年 | 4篇 |
1996年 | 5篇 |
1995年 | 3篇 |
1993年 | 3篇 |
1992年 | 1篇 |
1991年 | 2篇 |
1989年 | 2篇 |
1988年 | 2篇 |
1987年 | 2篇 |
1986年 | 2篇 |
1984年 | 1篇 |
1983年 | 1篇 |
1981年 | 1篇 |
1976年 | 1篇 |
1975年 | 1篇 |
1971年 | 1篇 |
排序方式: 共有87条查询结果,搜索用时 15 毫秒
41.
Involvement of sinoaortic afferents in renal sympathoinhibition and vasodilation induced by acute hypernatremia
下载免费PDF全文
![点击此处可从《Clinical and experimental pharmacology & physiology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Elaine F Silva Celisa TN Sera Aline A Mourão Paulo R Lopes Marina CS Moreira Marcos L Ferreira‐Neto Débora AS Colombari Sérgio LD Cravo Gustavo R Pedrino 《Clinical and experimental pharmacology & physiology》2015,42(11):1135-1141
Despite the abundance of evidence that supports the important role of aortic and carotid afferents to short‐term regulation of blood pressure and detection of variation in the arterial PO2, PCO2 and pH, relatively little is known regarding the role of these afferents during changes in the volume and composition of extracellular compartments. The present study sought to determine the involvement of these afferents in the renal vasodilation and sympathoinhibition induced by hypertonic saline (HS) infusion. Sinoaortic‐denervated and sham male Wistar rats were anaesthetised with intravenous (i.v.) urethane (1.2 g/kg body weight (bw)) prior to the measurement of the mean arterial pressure (MAP), renal vascular conductance (RVC) and renal sympathetic nerve activity (RSNA). In the sham group, the HS infusion (3 mol/L NaCl, 1.8 mL/kg bw, i.v.) induced transient hypertension (12 ± 4 mmHg from baseline, peak at 10 min; P < 0.05), an increase in RVC (127 ± 9% and 150 ± 13% from baseline, at 20 and 60 min respectively; P < 0.05) and a decrease in RSNA (?34 ± 10% and ?29 ± 5% from baseline, at 10 and 60 min respectively; P < 0.05). In sinoaortic‐denervated rats, HS infusion promoted a sustained pressor response (30 ± 5 and 17 ± 6 mmHg of baseline values, at 10 and 30 min respectively; P < 0.05) and abolished the increase in RVC (85 ± 8% from baseline, at 10 min) and decrease in RSNA (?4 ± 3% from baseline, at 10 min). These results suggest that aortic and carotid afferents are involved in cardiovascular and renal sympathoinhibition responses induced by acute hypernatremia. 相似文献
42.
Background
Systemic embolism is a serious and sometime fatal complication of rheumatic MS.Objective
We assessed the predictive power of D-Dimer level to predict occurrence of left atrial (LA) thrombi in patients with rheumatic mitral stenosis (MS).Methods
D-dimer levels were analyzed for 24 patients with rheumatic MS with LA clot and 22 patients with rheumatic MS with no LA clot undergoing transeosophageal echocardiography. A level more than 4 µg/ml was taken as elevated to predict the presence of LA clot in the study groups.Results
For a cut-off value of 4 µg/ml, sensitivity was 66.67 % and specificity 100 % for prediction of LA clot and AUC 0.710. A cut-off value of less than 1 µg/ml, sensitivity was 91.67 % and 87. 5 % negative predictive value for ruling out presence of LA clot and AUC 0.721.Conclusion
A higher value of D-dimer can predict the possible presence of a LA clot and very low value can predict absence of clot in patients with rheumatic MS. 相似文献43.
The Intelence aNd pRezista Once A Day Study (INROADS): a multicentre,single‐arm,open‐label study of etravirine and darunavir/ritonavir as dual therapy in HIV‐1‐infected early treatment‐experienced subjects
下载免费PDF全文
![点击此处可从《HIV medicine》网站下载免费的PDF全文](/ch/ext_images/free.gif)
PJ Ruane C Brinson M Ramgopal R Ryan B Coate M Cho TN Kakuda D Anderson 《HIV medicine》2015,16(5):288-296
44.
45.
46.
Di-(2-ethylhexyl) phthalate (DEHP) accumulates in blood brought into contact with materials utilizing this compound as a plasticizer. To determine whether this phthalate diester affects red blood cell integrity, we have compared cell morphology, plasma hemoglobin accumulation, micro-vesicle production, and the concentration of intracellular metabolites and electrolytes of erythrocytes from blood stored at 4 degrees C with and without DEHP. When sufficient emulsified DEHP was mixed with blood to give a final concentration of 300 micrograms/mL, plasma hemoglobin accumulation was reduced by an average of 70%, the percentage of cells exhibiting normal morphology was enhanced by at least 20-fold, and the volume of microvesicles released from red blood cells was reduced by 50% after 35 days of refrigerated storage compared to the values obtained from corresponding samples stored without added phthalate. Similar effects were observed regardless of whether blood was stored in nonplasticized polypropylene or tri-(2-ethylhexyl) trimellitate plasticized polyvinylchloride containers and with DEHP solubilized by a variety of emulsifiers. When 300 micrograms/mL DEHP was added to stored blood containing erythrocytes predominantly in the echinocyte conformation, many of the cells reverted to the normal discoid morphology. The addition of this quantity of DEHP to blood had no significant effect on the course of storage-induced changes in erythrocyte adenosine triphosphate (ATP), 2,3-diphosphoglycerate (2,3-DPG), sodium or potassium concentrations. The data are consistent with the hypothesis that DEHP inhibits the deterioration of the red blood cell membrane that results from the refrigerated storage of whole blood. 相似文献
47.
Sandra V Kik Sandra PJ Olthof Jonie TN de Vries Dick Menzies Naomi Kincler Joke van Loenhout-Rooyakkers Conny Burdo Suzanne Verver 《BMC public health》2009,9(1):283
Background
In low tuberculosis (TB) incidence countries TB affects mostly immigrants in the productive age group. Little empirical information is available about direct and indirect TB-related costs that patients face in these high-income countries. We assessed the direct and indirect costs of immigrants with TB in the Netherlands. 相似文献48.
W J Stauble 《Revue canadienne de psychiatrie》1988,33(3):213-217
Therapeutic Community is forty years old. This paper describes its origins and reviews the more important contributions in the English speaking literature of the last decade. There have been few contributions from Canadians in spite of an upsurge of interest in Group Psychotherapy in the last few years. Some experiences in Toronto are reported. 相似文献
49.
50.
Laparoscopic repair of a strangulated Bochdalek hernia 总被引:1,自引:0,他引:1
Background Bochdalek herniae are rare. They are usually repaired by open abdominal surgery or by a thoracic video-assisted approach.
When strangulated and in a compromised patient the options are fewer.
Aim To describe a case treated by a laparoscopic approach.
Results The procedure was technically difficult, but the patient recovered without recurrence.
Conclusion Laparoscopic repair is possible even with strangulation. 相似文献