全文获取类型
收费全文 | 2693330篇 |
免费 | 194996篇 |
国内免费 | 7678篇 |
专业分类
耳鼻咽喉 | 36090篇 |
儿科学 | 89044篇 |
妇产科学 | 74235篇 |
基础医学 | 380322篇 |
口腔科学 | 73312篇 |
临床医学 | 244218篇 |
内科学 | 534666篇 |
皮肤病学 | 65656篇 |
神经病学 | 224464篇 |
特种医学 | 104348篇 |
外国民族医学 | 738篇 |
外科学 | 402613篇 |
综合类 | 50969篇 |
现状与发展 | 5篇 |
一般理论 | 1004篇 |
预防医学 | 202837篇 |
眼科学 | 59176篇 |
药学 | 195895篇 |
8篇 | |
中国医学 | 5483篇 |
肿瘤学 | 150921篇 |
出版年
2021年 | 21115篇 |
2019年 | 21843篇 |
2018年 | 31861篇 |
2017年 | 24708篇 |
2016年 | 28854篇 |
2015年 | 31817篇 |
2014年 | 42958篇 |
2013年 | 64965篇 |
2012年 | 86343篇 |
2011年 | 91366篇 |
2010年 | 54720篇 |
2009年 | 51643篇 |
2008年 | 85622篇 |
2007年 | 90923篇 |
2006年 | 92228篇 |
2005年 | 88371篇 |
2004年 | 85019篇 |
2003年 | 82260篇 |
2002年 | 79389篇 |
2001年 | 131216篇 |
2000年 | 134845篇 |
1999年 | 112691篇 |
1998年 | 32240篇 |
1997年 | 28734篇 |
1996年 | 28839篇 |
1995年 | 27935篇 |
1994年 | 25612篇 |
1993年 | 23949篇 |
1992年 | 85758篇 |
1991年 | 82123篇 |
1990年 | 79295篇 |
1989年 | 76590篇 |
1988年 | 69909篇 |
1987年 | 68496篇 |
1986年 | 63993篇 |
1985年 | 61129篇 |
1984年 | 45504篇 |
1983年 | 38423篇 |
1982年 | 22954篇 |
1981年 | 20441篇 |
1979年 | 39406篇 |
1978年 | 27846篇 |
1977年 | 23672篇 |
1976年 | 21876篇 |
1975年 | 23225篇 |
1974年 | 27167篇 |
1973年 | 25705篇 |
1972年 | 24030篇 |
1971年 | 22256篇 |
1970年 | 20449篇 |
排序方式: 共有10000条查询结果,搜索用时 46 毫秒
71.
Nicholas E. Anton Tomoko Mizota Lava R. Timsina Jake A. Whiteside Erinn M. Myers Dimitrios Stefanidis 《American journal of surgery》2019,217(2):266-271
Introduction
Several studies demonstrated that simulator-acquired skill transfer to the operating room is incomplete. Our objective was to identify trainee characteristics that predict the transfer of simulator-acquired skill to the operating room.Methods
Trainees completed baseline assessments including intracorporeal suturing (IS) performance, attentional selectivity, self-reported use of mental skills, and self-reported prior clinical and simulated laparoscopic experience and confidence. Residents then followed proficiency-based laparoscopic skills training, and their skill transfer was assessed on a live-anesthetized porcine model. Predictive characteristics for transfer test performance were assessed using multiple linear regression.Results
Thirty-eight residents completed the study. Automaticity, attentional selectivity, resident perceived ability with laparoscopy and simulators, and post-training IS performance were predictive of IS performance during the transfer test.Conclusions
Promoting automaticity, self-efficacy, and attention selectivity may help improve the transfer of simulator-acquired skill. Mental skills training and training to automaticity may therefore be valuable interventions to achieve this goal. 相似文献72.
73.
Bela Anand-Apte Jennifer R. Chao Ruchira Singh Heidi Stöhr 《Journal of neuroscience research》2019,97(1):88-97
Sorsby fundus dystrophy (SFD), an autosomal dominant, fully penetrant, degenerative disease of the macula, is manifested by symptoms of night blindness or sudden loss of visual acuity, usually in the third to fourth decades of life due to choroidal neovascularization (CNV). SFD is caused by specific mutations in the Tissue Inhibitor of Metalloproteinase-3, (TIMP3) gene. The predominant histo-pathological feature in the eyes of patients with SFD are confluent 20–30 m thick, amorphous deposits found between the basement membrane of the retinal pigment epithelium (RPE) and the inner collagenous layer of Bruch's membrane. SFD is a rare disease but it has generated significant interest because it closely resembles the exudative or “wet” form of the more common age-related macular degeneration (AMD). In addition, in both SFD and AMD donor eyes, sub-retinal deposits have been shown to accumulate TIMP3 protein. Understanding the molecular functions of wild-type and mutant TIMP3 will provide significant insights into the patho-physiology of SFD and perhaps AMD. This review summarizes the current knowledge on TIMP3 and how mutations in TIMP3 cause SFD to provide insights into how we can study this disease going forward. Findings from these studies could have potential therapeutic implications for both SFD and AMD. 相似文献
74.
75.
76.
Alina Goldenberg B.A. Catalina Matiz M.D. Lawrence F. Eichenfield M.D. 《Pediatric dermatology》2015,32(4):e191-e192
Henna, derived from a combination of natural leaves and coloring additives, is a common decorative dye traditionally used in many Islamic religious celebrations. Para‐phenylenediamine (PPD), a major component of black henna tattoo, is a strong sensitizer and common allergen. We report a case of severe connubial allergic contact dermatitis after black henna heterotransfer in a girl. 相似文献
77.
78.
79.
Autoimmune comorbid diseases associated with lichen planus: a nationwide case–control study 下载免费PDF全文
80.
M.T. Leccia N. Auffret F. Poli J.‐P. Claudel S. Corvec B. Dreno 《Journal of the European Academy of Dermatology and Venereology》2015,29(8):1485-1492
Acne vulgaris (acne) is a chronic inflammatory disease of the sebaceous gland, characterized by follicular hyperkeratinization, excessive colonization by Propionibacterium acnes (P. acnes) as well as immune reactions and inflammation. Despite an armamentarium of topical treatments available including benzoyl peroxide, retinoids and azelaic acid, topical antibiotics in monotherapies, especially erythromycin and clindamycin, are still used in Europe to treat acne. This intensive use led to antimicrobial‐resistant P. acnes and staphylococci strains becoming one of the main health issues worldwide. This is an update on the current topical acne treatments available in Europe, their mechanism of action, their potential to induce antimicrobial resistance and their clinical efficacy and safety. 相似文献