Acute hepatitis associated withCampylobacter jejuni bacteraemia

A case of acute hepatitis associated withCampylobacter jejuni bacteraemia is reported. Transaminase levels were increased over 50-fold in a patient with clinical features of enteritis and septicaemia.Campylobacter jejuni was isolated from blood and faecal cultures. Other infective and noninfective causes of acute hepatitis were excluded. The patient's symptoms and liver function values improved after antimicrobial therapy. Hepatitis should be considered as a complication of humanCampylobacter jejuni infection.     

Quality of data reported to a smaller-hospital pilot surveillance program.

This data quality study assessed the accuracy of data collected as part of a pilot smaller-hospital surveillance program for methicillin-resistant Staphylococcus aureus (MRSA) infection and bloodstream infection (BSI). For reported MRSA infection, estimated values were as follows: sensitivity, 40%; specificity, 99.9%; and positive predictive value, 33.3%. For reported BSI, estimated values were as follows: sensitivity, 42.9%; specificity, 99.8%; and positive predictive value, 37.5%.     

Chronic or recurring cough in children—a presentation of asthma?

Thirty-five children between the ages of one year and 11 years who presented with chronic or recurring cough over a two-year period were treated for asthma. They were given bronchodilator syrup for a trial period of one month. All the children improved symptomatically.

It is suggested that any child with a persistent cough or recurring cough should be given bronchodilator syrup even in the absence of wheeze and particularly when there is a family history of asthma. This might result in the early diagnosis of unrecognized asthma and help to reduce the amount of unnecessary antibiotics and cough linctus that these children receive.

     

Single-acquisition chemical-shift imaging of a binary system with use of stimulated echoes

A method for separating binary chemical-shift components with a single image data acquisition by means of stimulated echoes is demonstrated. With a strategy analogous to the modified Dixon method, three stimulated echoes were acquired to form three complex images. In each of the images, the complex pixel intensities were imparted, by design of the pulse sequence, with a phase factor carrying chemical-shift or field inhomogeneity information. With these three images, true fat/water separation can be obtained in biologic tissues. Studies at high field strength (4.7 T) on a toluene phantom, a pseudo-binary chemical-shift system, were used to evaluate the applicability of the method. Its clinical feasibility was demonstrated on a healthy human subject in a 0.6-T whole-body imaging system.     

山莨菪碱和蝙蝠葛碱对白三烯和PAF诱导的牛脑前动脉平滑肌细胞DNA合成的影响(英文)

白三烯和血小板活化因子在低于nmol浓度时就能刺激培养的牛脑前动脉平滑肌细胞的DNA合成,在10~(-7)mol/L时达最大刺激。LTB_4,LTD_4和PAF在10~(-7)mol/L时对上述细胞DNA合成的刺激率分别为32％,29％和77％。山莨菪碱和蝙蝠葛碱在10~(-7)～10~(-4)mol/L范围内呈剂量依赖性地抑制白三烯和血小板活化因子的上述作用。