全文获取类型
收费全文 | 27392篇 |
免费 | 1795篇 |
国内免费 | 172篇 |
专业分类
耳鼻咽喉 | 342篇 |
儿科学 | 846篇 |
妇产科学 | 801篇 |
基础医学 | 2882篇 |
口腔科学 | 747篇 |
临床医学 | 2332篇 |
内科学 | 6052篇 |
皮肤病学 | 588篇 |
神经病学 | 1486篇 |
特种医学 | 890篇 |
外国民族医学 | 9篇 |
外科学 | 4622篇 |
综合类 | 721篇 |
现状与发展 | 1篇 |
一般理论 | 22篇 |
预防医学 | 1958篇 |
眼科学 | 802篇 |
药学 | 2289篇 |
中国医学 | 161篇 |
肿瘤学 | 1808篇 |
出版年
2023年 | 395篇 |
2022年 | 1099篇 |
2021年 | 1624篇 |
2020年 | 833篇 |
2019年 | 1066篇 |
2018年 | 1395篇 |
2017年 | 857篇 |
2016年 | 878篇 |
2015年 | 980篇 |
2014年 | 1243篇 |
2013年 | 1501篇 |
2012年 | 2087篇 |
2011年 | 2155篇 |
2010年 | 1101篇 |
2009年 | 920篇 |
2008年 | 1371篇 |
2007年 | 1475篇 |
2006年 | 1292篇 |
2005年 | 1113篇 |
2004年 | 1037篇 |
2003年 | 865篇 |
2002年 | 804篇 |
2001年 | 337篇 |
2000年 | 321篇 |
1999年 | 307篇 |
1998年 | 171篇 |
1997年 | 124篇 |
1996年 | 113篇 |
1995年 | 115篇 |
1994年 | 77篇 |
1993年 | 59篇 |
1992年 | 132篇 |
1991年 | 122篇 |
1990年 | 117篇 |
1989年 | 108篇 |
1988年 | 101篇 |
1987年 | 94篇 |
1986年 | 103篇 |
1985年 | 88篇 |
1984年 | 70篇 |
1983年 | 87篇 |
1982年 | 35篇 |
1981年 | 47篇 |
1980年 | 34篇 |
1979年 | 79篇 |
1978年 | 45篇 |
1977年 | 53篇 |
1976年 | 41篇 |
1975年 | 44篇 |
1974年 | 38篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
991.
Baracco R Kapur G Mattoo T Jain A Valentini R Ahmed M Thomas R 《Journal of clinical hypertension (Greenwich, Conn.)》2012,14(5):316-321
Despite current guidelines, variability exists in the workup of hypertensive children due to physician preferences. The study evaluates primary vs secondary hypertension diagnosis from investigations routinely performed in hypertensive children. This retrospective study included children 5 to 19 years with primary and secondary hypertension. The proportions of abnormal laboratory and imaging tests were compared between primary and secondary hypertension groups. Risk factors for primary vs secondary hypertension were evaluated by logistic regression and likelihood function analysis. Patients with secondary hypertension were younger (5-12 years) and had a higher proportion of abnormal creatinine, renal ultrasound, and echocardiogram findings. There was no significant difference in abnormal results of thyroid function, urine catecholamines, plasma renin, and aldosterone. Abnormal renal ultrasound findings and age were predictors of secondary hypertension by regression and likelihood function analysis. Children aged 5 to 12 years with abnormal renal ultrasound findings and high diastolic blood pressures are at higher risk for secondary hypertension that requires detailed evaluation. 相似文献
992.
Khan FY Al-Muzrakchi AM Elbedawi MM Al-Muzrakchi AA Al Tabeb A 《Travel medicine and infectious disease》2012,10(1):25-31
There is limited information about peritoneal tuberculosis in Qatar. This retrospective study aimed to review our experience with peritoneal tuberculosis in patients admitted to Hamad general hospital over a period of 5 years, from 2005 to 2009, with emphasis on presentation, investigation, diagnosis and therapeutic outcome. Fifty-four patients with peritoneal tuberculosis identified during the study period were included. The mean age of them was 31.85 years and 96.3% (52/54) of them were non-Qataris with male predominance. The main symptoms and signs at the time of presentation were abdominal pain and ascites respectively. Underlying diseases were described in 24% (13/54) and history of contact with tuberculous cases was present in 31.5% (17/54) of patients. Tuberculin test was positive in 66.7% (36/54). The ascitic fluid smear showed acid fast bacilli in 2% (1/53), and culture was positive in 39.6% (21/53) of cases. Laparoscopically obtained peritoneal biopsy showed caseating granulomas in 93% (40/43) and mycobacteria were identified by acid fast staining and culture in 58.5% (24/41) and 98% (40/41) of the tested specimens respectively. Most of the patients (84%; 37/44) who had completed their therapy in Qatar improved with antituberculosis therapy, and only one patient died. In conclusion, the clinical features and the imaging findings of the disease were non-specific. A high index of suspicion is essential for early diagnosis. Culture of ascitic fluid delayed the diagnosis in clinically suspected cases, whereas laparoscopically guided peritoneal biopsy provided rapid and correct diagnosis. A Six-month course with antituberculous therapy was effective and improved the outcome. 相似文献
993.
994.
995.
Mermigkis C Bouloukaki I Mermigkis D Kallergis E Mavroudi E Varouchakis G Tzortzaki E Siafakas N Schiza SE 《Sleep & breathing》2012,16(3):813-819
Background??aim
C-reactive protein (CRP) is directly implicated in atherogenesis and associated cardiovascular morbidity in patients with obstructive sleep apnea (OSA). Effective continuous positive airway pressure (CPAP) treatment has been shown to gradually decrease CRP levels and thus consequently improve disease-related cardiovascular morbidity. However, the influence of gender on the CRP evolution pattern has never been assessed before. The aim of our study was to investigate possible gender differences in CRP evolution in OSA patients 3 and 6?months after the start of effective CPAP treatment.Methods
The study population consisted of 436 patients (252 males/184 females) with newly diagnosed moderate to severe OSA and good CPAP compliance assessed by a thorough follow up. High-sensitivity C-reactive protein (hs-CRP) was assessed before CPAP initiation and at the third and sixth month of the follow-up period.Results
C-reactive protein values showed a statistically significant decrease at the third and sixth month of CPAP therapy [initial values 0.79?±?0.65?mg/dL versus 0.70?±?0.52?mg/dL (p?0.05) after 3?months and 0.30?±?0.33?mg/dL (p?0.001) after 6?months of CPAP therapy]. When patients were divided into males and females, the above evolution pattern was changed. At the third month time point, the CRP values showed a statistically significant decrease only in males (from 0.74?±?0.53?mg/dL to 0.61?±?0.5?mg/dL, p?0.01) while females showed only minimal and insignificant changes (from 0.87?±?0.79?mg/dL to 0.83?±?0.51?mg/dL, p?>?0.05). After 6?months?? treatment, CRP decreased significantly in both genders (males from 0.74?±?0.53?mg/dL to 0.28?±?0.32?mg/dL, p?0.001 and females from 0.87?±?0.79?mg/dL to 0.34?±?0.36?mg/dL, p?0.001).Conclusion
Our results suggest a delay in the normalization of CRP levels in females despite effective CPAP treatment. A time period of at least 6?months appeared to be required in women in order to reduce CRP levels and consequent cardiovascular risk. In contrast, CPAP??s protective role in males is achieved at an earlier time point. Gender-related hormonal and genetic factors may influence the above CRP evolution pattern. 相似文献996.
Glaucoma is a common cause of vision loss after corneal transplantion and is considered a major risk factor for graft failure. Glaucoma may be present before corneal transplant surgery, or increased intraocular pressure may develop after keratoplasty in up to one-third of patients. Pre-existing glaucoma should be controlled before keratoplasty, either medically or surgically. For postkeratoplasty increase in intraocular pressure; identifying the risk factors allows appropiate follow-up and management. Patients undergoing anterior lamellar keratoplasty may take advantage of reduced rates of postkeratoplasty glaucoma. Glaucoma also complicates eyes with endothelial keratoplasties, mostly related to management of intraocular pressure spikes derived from anterior chamber air bubbles. Nevertheless, the severity is less, and the intraocular pressure is more easily controlled when compared with penetrating keratoplasty. Adequate management of glaucoma that develops before or after keratoplasty may save eyes from irreversible damage to the optic nerve and increase graft survival. 相似文献
997.
Wassef Amr Mohamed Abdelaziz Abdelhakim Mohamad Amr Salah Eddin Macky Tamer Ahmed Raafat Karim Adly Youssef Maha Mohamed 《International ophthalmology》2021,41(12):4163-4174
International Ophthalmology - To investigate the retinal microvascular and choroidal thickness changes in eyes with active Beh?et’s disease posterior uveitis and post-remission. A... 相似文献
998.
999.