全文获取类型
收费全文 | 6382篇 |
免费 | 378篇 |
国内免费 | 71篇 |
专业分类
耳鼻咽喉 | 65篇 |
儿科学 | 121篇 |
妇产科学 | 145篇 |
基础医学 | 1116篇 |
口腔科学 | 716篇 |
临床医学 | 430篇 |
内科学 | 1153篇 |
皮肤病学 | 139篇 |
神经病学 | 519篇 |
特种医学 | 260篇 |
外科学 | 516篇 |
综合类 | 38篇 |
一般理论 | 1篇 |
预防医学 | 686篇 |
眼科学 | 63篇 |
药学 | 530篇 |
中国医学 | 58篇 |
肿瘤学 | 275篇 |
出版年
2023年 | 52篇 |
2022年 | 132篇 |
2021年 | 179篇 |
2020年 | 124篇 |
2019年 | 173篇 |
2018年 | 233篇 |
2017年 | 154篇 |
2016年 | 179篇 |
2015年 | 201篇 |
2014年 | 297篇 |
2013年 | 330篇 |
2012年 | 478篇 |
2011年 | 551篇 |
2010年 | 288篇 |
2009年 | 225篇 |
2008年 | 380篇 |
2007年 | 425篇 |
2006年 | 295篇 |
2005年 | 314篇 |
2004年 | 247篇 |
2003年 | 225篇 |
2002年 | 167篇 |
2001年 | 121篇 |
2000年 | 124篇 |
1999年 | 118篇 |
1998年 | 84篇 |
1997年 | 64篇 |
1996年 | 51篇 |
1995年 | 38篇 |
1994年 | 31篇 |
1993年 | 35篇 |
1992年 | 62篇 |
1991年 | 44篇 |
1990年 | 52篇 |
1989年 | 51篇 |
1988年 | 56篇 |
1987年 | 32篇 |
1986年 | 29篇 |
1985年 | 27篇 |
1984年 | 15篇 |
1983年 | 13篇 |
1982年 | 17篇 |
1981年 | 11篇 |
1980年 | 11篇 |
1979年 | 13篇 |
1977年 | 15篇 |
1976年 | 7篇 |
1975年 | 8篇 |
1973年 | 6篇 |
1971年 | 6篇 |
排序方式: 共有6831条查询结果,搜索用时 10 毫秒
101.
102.
103.
Priscilla Soares Elizângela Silva de Brito Fernando Paiva Dante Pavan Lúcio André Viana 《Parasitology research》2014,113(12):4499-4503
The study objectives were to characterize the morphology of the parasitic forms and describe the prevalence and intensity of Haemogregarina spp. in a population of the turtle Podocnemis unifilis as well as to examine the relationships between parasitism and turtle variables such as gender, size, and weight. Samples were taken in the Tapajós and Jamanxim rivers, Itaituba, Pará state, Brazil. Blood was collected from the tail vein of 72 P. unifilis specimens, including 35 males, 36 females, and one unsexed juvenile. The prevalence of Haemogregarina spp. was 98 % (n?=?71). The mean parasite intensity of Haemogregarina spp. was 118 (1–582) parasites/2000 blood cells (6 %). There was no significant difference in the mean parasite intensity between male (137.68?±?121.8, n?=?35) and female turtles (101.42?±?123.59, n?=?35). There was no relationship between parasite intensity and carapace length. Although the relationship between parasite intensity and host body weight was significant, the relationship was weak. This is the first study on Haemogregarina parasitism with a relatively high number of turtles in Brazil. 相似文献
104.
Kátia C. Carvalho Beatriz M. Maia Samantha V. Omae Antonio A. Rocha Luiz P. Covizzi José Vassallo Rafael M. Rocha Fernando A. Soares 《Acta histochemica》2014
There is a lack of standardization of a best practice protocol for Phosphatase and Tensin Homolog (PTEN) assessment by immunohistochemistry in anatomic pathology routine practice. We performed immunohistochemistry for 19 antibodies against PTEN, eleven of which were excluded during the standardization step. Immunohistochemistry of the remaining eight antibodies was performed on a Tissue Microarray containing 55 prostate and 40 renal carcinoma samples. Fluorescent in situ hybridization (FISH) was used as reference standard for immunohistochemistry specificity evaluation. Concerning nuclear staining, polyclonal (Cat#22034-1-AP); 6H2.1 mMAb (Cat#ABM-2052), Y184 RabMAb (Cat#NB110-57441) and 217702 mMAb antibodies presented the highest agreement with fluorescent in situ hybridization (p < 0.001 for all) and with regard to cytoplasmic staining, Y184 RabMAb (Cat#NB110-57441); polyclonal (Cat#22034-1-AP) and 217702 mMAb presented the highest agreement (p < 0.001 for all). Our results indicate that several commercially available antibodies do not show reliability of sensitivity and specificity for PTEN evaluation and we propose 6H2.1 mMAb (Cat#ABM-2052) as the antibody of choice for laboratory standardization and best practice in clinical routine, which demonstrated excellent sensitivity for both nuclear and cytoplasmic staining, specificity for PTEN by Western blot and good correlation with PTEN status by FISH with regard to nuclear staining. 相似文献
105.
Silveira C. R. Varela Junior A. S. Corcini C. D. Soares S. L. Anciuti A. N. Kütter M. T. Martínez P. E. 《Ecotoxicology (London, England)》2019,28(8):913-922
Ecotoxicology - Bisphenol-A (BPA) is a potential endocrine disruptor besides being associated with oxidative damage in several vertebrate classes. In the present study we investigated oxidative... 相似文献
106.
Maria G.R. Pucciarelli Adolfo C.O. Lopes José F.S. Lopes Simone Soares 《The Journal of prosthetic dentistry》2019,121(1):9-12
The multidisciplinary teams involved in the treatment of individuals with cleft lip and palate are challenged when implants are indicated in the cleft area. Difficulties include obtaining a healthy peri-implant area and, especially, obtaining the natural-looking papilla essential for esthetic success. The area affected by the cleft has a bone deficiency, which is typically augmented with an alveolar bone graft at adolescence. Guidelines for the 3-dimensional placement of implants at the cleft area are presented based on clinical reports. The patients were followed up for at least 1 year. Adoption of the proposed guidelines enables satisfactory esthetic and functional outcomes in patients with cleft lip and palate. 相似文献
107.
Mariana D. Bellinaso Fabio Z. M. Soares Rachel de Olivera Rocha 《Journal of investigative and clinical dentistry》2019,10(4)
The aim of the present study was to compare the restorative time for filling cavities in posterior teeth using bulk‐fill and conventional resin composites through a systematic review and meta‐analysis. A search for clinical trials and laboratory studies was performed in PubMed/MEDLINE, Scopus, the Latin American and Caribbean Health Sciences Literature database, the Brazilian Library in Dentistry, Cochrane Library, Clinical Trials, and ReBEC (Registro Brasileiro de Ensaios Clínicos) databases without publication year or language restriction. Two reviewers identified eligible studies according to the inclusion criteria: bulk‐fill compared to conventional resin in class I or II, and the restorative time as an outcome. A meta‐analysis of the restorative time mean difference between composites was performed (inverse variance method, random effects model; Z‐test, P ≤ .05). From the 662 eligible studies, 133 were selected for full‐text analysis; three were included in the systematic review and in the meta‐analysis. Overall, the restorative time was lower when bulk‐fill was used (P = .0007, Z = 3.37), as the subgroup full‐body bulk‐fill (P < .00001, Z = 21.00). There was no difference in restorative time between flowable bulk‐fill and conventional resins (P = .08, Z = 1.76). Moderate‐to‐substantial heterogeneity was detected. Full‐body bulk‐fill composites decrease the restorative time in posterior teeth compared to conventional resins. Full‐body bulk‐fill resins require a shorter restorative time to perform restorations in posterior teeth than conventional resins, but the same is not valid for flowable bulk‐fill resin composites. 相似文献
108.
Igor Bastos Polonio Milena Marques Pagliareli Acencio Rogério Pazetti Francine Maria de Almeida Bárbara Soares da Silva Karina Aparecida Bonifácio Pereira Rogério Souza 《Jornal brasileiro de pneumologia》2014,40(4):421-424
We assessed the effects of lodenafil on hemodynamics and inflammation in the rat
model of monocrotaline-induced pulmonary hypertension (PH). Thirty male
Sprague-Dawley rats were randomly divided into three groups: control; monocrotaline
(experimental model); and lodenafil (experimental model followed by lodenafil
treatment, p.o., 5 mg/kg daily for 28 days) Mean pulmonary artery pressure (mPAP) was
obtained by right heart catheterization. We investigated right ventricular
hypertrophy (RVH) and IL-1 levels in lung fragments. The number of cases of RVH was
significantly higher in the monocrotaline group than in the lodenafil and control
groups, as were mPAP and IL-1 levels. We conclude that lodenafil can prevent
monocrotaline-induced PH, RVH, and inflammation. 相似文献
109.
Kathy Scott-Gurnell Ify Ezeobele Jena Blake Tiffany Gerondale Marsal Sanches Patricia M. Averill Jair C. Soares 《Comprehensive psychiatry》2014
Objective
There are still several concerns regarding the inconsistency in the diagnosis of Bipolar Disorder (BD) in children and adolescents. This study reviews the symptoms of youth admitted to The University of Texas Harris County Psychiatric Center (UT-HCPC) prior to a confirmed diagnosis of BD to elucidate patterns and target symptoms which may facilitate early recognition of BD.Methods
This is a retrospective review of charts of adult patients with a discharge diagnosis of BD for three consecutive admissions who were also admitted to UT-HCPC as children or adolescents (N = 26). The Kiddie SADS was completed based on each patient’s first admission as a child and last admission as an adult.Results
Most of the symptoms found in adult BD were present in the child/adolescent subjects at equivalent rates, except for mood elevation, which was less common during childhood and adolescence. In spite of the psychopathological similarity, only 6 (23%) of the subjects were diagnosed with BD as youth.Conclusion
BD is poorly diagnosed among children and adolescents. Difficulties in the assessment of the youth, as well as particularities in the psychopathology of mood among children and adolescents may account for the low diagnostic rate. 相似文献110.