全文获取类型
收费全文 | 6117篇 |
免费 | 438篇 |
国内免费 | 98篇 |
专业分类
耳鼻咽喉 | 73篇 |
儿科学 | 211篇 |
妇产科学 | 90篇 |
基础医学 | 999篇 |
口腔科学 | 89篇 |
临床医学 | 576篇 |
内科学 | 1252篇 |
皮肤病学 | 139篇 |
神经病学 | 564篇 |
特种医学 | 464篇 |
外科学 | 773篇 |
综合类 | 73篇 |
现状与发展 | 2篇 |
预防医学 | 295篇 |
眼科学 | 116篇 |
药学 | 462篇 |
中国医学 | 44篇 |
肿瘤学 | 431篇 |
出版年
2023年 | 51篇 |
2022年 | 154篇 |
2021年 | 262篇 |
2020年 | 124篇 |
2019年 | 177篇 |
2018年 | 170篇 |
2017年 | 137篇 |
2016年 | 182篇 |
2015年 | 256篇 |
2014年 | 303篇 |
2013年 | 346篇 |
2012年 | 487篇 |
2011年 | 476篇 |
2010年 | 276篇 |
2009年 | 233篇 |
2008年 | 331篇 |
2007年 | 326篇 |
2006年 | 319篇 |
2005年 | 227篇 |
2004年 | 239篇 |
2003年 | 152篇 |
2002年 | 161篇 |
2001年 | 125篇 |
2000年 | 106篇 |
1999年 | 83篇 |
1998年 | 61篇 |
1997年 | 65篇 |
1996年 | 44篇 |
1995年 | 46篇 |
1994年 | 39篇 |
1993年 | 24篇 |
1992年 | 42篇 |
1991年 | 44篇 |
1990年 | 54篇 |
1989年 | 63篇 |
1988年 | 28篇 |
1987年 | 46篇 |
1986年 | 42篇 |
1985年 | 41篇 |
1984年 | 28篇 |
1983年 | 28篇 |
1981年 | 15篇 |
1980年 | 19篇 |
1979年 | 20篇 |
1977年 | 15篇 |
1976年 | 19篇 |
1975年 | 15篇 |
1972年 | 15篇 |
1971年 | 18篇 |
1970年 | 14篇 |
排序方式: 共有6653条查询结果,搜索用时 15 毫秒
991.
992.
993.
Krzysztof Banaszkiewicz Emilia J. Sitek Monika Rudzińska Witold So?tan Jaros?aw S?awek Andrzej Szczudlik 《Journal of neural transmission (Vienna, Austria : 1996)》2012,119(11):1361-1365
The aim of this study was to identify determinants of functional disability, patient’s quality of life (QoL) and caregivers’ burden in Huntington’s disease (HD). Eighty HD patients participated in the study. Motor and behavioral disturbances as well as cognitive impairment were assessed using motor, behavioral and cognitive parts of the Unified Huntington Disease Rating Scale (UHDRS); Hamilton Depression Rating Scale was used to assess depression. Disability, health-related QoL and the impact of the disease on the caregivers were assessed using the following methods: UHDRS Functional Assessment Score, SF-36 Scale and Caregiver Burden Inventory. Multiple regression analysis showed that motor disturbances, cognitive impairment, apathy and disease duration were the independent predictors of disability. Depression and cognitive disturbances were the determinants of patient’s QoL, while motor disturbances and depression were the predictors of the caregiver burden. Patient’s disability and QoL as well as caregivers’ burden should be taken into consideration while planning treatment strategy and the results of the present study show that the predictors of those treatment targets are different. 相似文献
994.
Safka Brožková D Nevšímalová S Mazanec R Rautenstrauss B Seeman P 《Neuromuscular disorders : NMD》2012,22(8):742-746
Charcot-Marie-Tooth neuropathies (CMT) are a group of clinically and genetically heterogeneous disorders of the peripheral nervous system. Selection of candidate disease genes for mutation analysis is sometimes difficult since more than 40 genes and loci are known to be associated with CMT neuropathies. Hence a Czech family Cz-CMT with demyelinating type of autosomal dominant CMT disease was investigated by genome-wide linkage analysis by means of single-nucleotide polymorphism (SNP) arrays. Among 35 regions with linkage, five carried known CMT genes. In the final result a novel early growth response 2 - missense mutation c.1235 A>G, p.Glu412Gly was found. Surprisingly, the more severely affected proband carried an additional heterozygous myelin protein zero variant p.Asp246Asn detected previously, which may modify the phenotype. However, this MPZ variant is benign in heterozygous state alone, because it is also carried by the patient's healthy father. 相似文献
995.
996.
997.
998.
Ono K Takenaka M Yokoyama E Oka S Baba T So T So T Uramoto H Takenoyama M Hanagiri T Yasumoto K 《Kyobu geka. The Japanese journal of thoracic surgery》2011,64(2):93-6; discussion 97-8
This study aims to investigate the therapeutic and prognostic implications of esophageal cancer in patients with other primary cancer. Between April 1992 and December 2008, in 83 patients underwent surgery for esophageal cancer at our department. Among them, 24 patients (28.9%) had medical history of additional primary cancer. There were 16 metachronous cancers and 8 synchronous cancers. Six patients had antecedent other primary cancers, and subsequent primary cancers developed in 10 patients. The other primary cancers included head and neck cancer in 8 patients, gastric cancer in 8, lung cancer in 6, colorectal cancer in 3, and other cancer in 3. The patients with other primary cancers were both heavy smokers and heavy drinkers in comparison to those without other primary cancers. The post-operative 5-year survival rate in patients with subsequent cancers, antecedent cancers, and synchronous cancers were 100%, 70.0%, and 46.9%. The 5-year survival rate was 33.4% in patients without other primary cancers. A high incidence of multiple primary cancers was observed in patients with esophageal carcinoma but the prognosis of these patients with metachronous cancers are better than that of patient with synchronous cancers and patients without other primary cancers. Post-operative follow up is considered to be necessary for early detection of multiple occurrences of carcinoma, especially in the upper aerodigestive tract. 相似文献
999.
1000.