全文获取类型
收费全文 | 38161篇 |
免费 | 2790篇 |
国内免费 | 119篇 |
专业分类
耳鼻咽喉 | 366篇 |
儿科学 | 1069篇 |
妇产科学 | 668篇 |
基础医学 | 5490篇 |
口腔科学 | 647篇 |
临床医学 | 3989篇 |
内科学 | 8209篇 |
皮肤病学 | 774篇 |
神经病学 | 3891篇 |
特种医学 | 1444篇 |
外国民族医学 | 11篇 |
外科学 | 5239篇 |
综合类 | 435篇 |
一般理论 | 30篇 |
预防医学 | 3073篇 |
眼科学 | 729篇 |
药学 | 2645篇 |
中国医学 | 93篇 |
肿瘤学 | 2268篇 |
出版年
2023年 | 309篇 |
2022年 | 502篇 |
2021年 | 977篇 |
2020年 | 675篇 |
2019年 | 901篇 |
2018年 | 1076篇 |
2017年 | 854篇 |
2016年 | 968篇 |
2015年 | 1018篇 |
2014年 | 1389篇 |
2013年 | 1716篇 |
2012年 | 2696篇 |
2011年 | 2808篇 |
2010年 | 1587篇 |
2009年 | 1311篇 |
2008年 | 2142篇 |
2007年 | 2296篇 |
2006年 | 2181篇 |
2005年 | 1975篇 |
2004年 | 1872篇 |
2003年 | 1573篇 |
2002年 | 1469篇 |
2001年 | 609篇 |
2000年 | 614篇 |
1999年 | 556篇 |
1998年 | 338篇 |
1997年 | 255篇 |
1996年 | 254篇 |
1995年 | 228篇 |
1994年 | 191篇 |
1993年 | 147篇 |
1992年 | 326篇 |
1991年 | 297篇 |
1990年 | 316篇 |
1989年 | 256篇 |
1988年 | 262篇 |
1987年 | 288篇 |
1986年 | 297篇 |
1985年 | 281篇 |
1984年 | 228篇 |
1983年 | 180篇 |
1982年 | 127篇 |
1979年 | 250篇 |
1978年 | 174篇 |
1977年 | 145篇 |
1976年 | 127篇 |
1975年 | 128篇 |
1974年 | 138篇 |
1973年 | 155篇 |
1972年 | 133篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
51.
The experience with the treatment of malignant histiocytosis has been disappointing. Despite modest treatment success with a combination of cyclophosphamide, Adriamycin (doxorubicin), vincristine and prednisone, the overall prognosis remains poor. There are only a few reports of prolonged complete remissions in pediatric patients. The following report describes two children who have had long-term remission with an aggressive combination chemotherapy program that included intrathecal prophylaxis. The chemotherapeutic regimen described merits further evaluation in a larger number of patients. 相似文献
52.
53.
Heat shock protein hsp72 induction in cortical and striatal astrocytes and neurons following infarction 总被引:3,自引:0,他引:3
F R Sharp D Lowenstein R Simon K Hisanaga 《Journal of cerebral blood flow and metabolism》1991,11(4):621-627
Transient global and transient focal ischemia induced the 72 kDa heat shock protein (hsp72) in neurons in cortex, striatum, and other regions known to be injured during transient ischemia. A novel finding was the induction of hsp72 in islands (cylinders in three dimensions) of cells composed of astrocytes around the perimeter and neurons in the interior. Since histology showed pale staining in these regions, it is proposed that these islands represent areas of focal infarction in the distribution of small cortical and lenticulostriate arteries. Although the factors responsible for hsp72 induction during ischemia and infarction are unknown, these results suggest differences in mechanisms of hsp72 induction in astrocytes compared to neurons. 相似文献
54.
Delineating the sites and progression of in vivo atrophy in multiple system atrophy using fluid-registered MRI. 总被引:1,自引:0,他引:1
Jonathan M Schott Jessica E Simon Nick C Fox Andrew P King M Nadeem Khan Lisa Cipolotti Dominic C Paviour John M Stevens Martin N Rossor 《Movement disorders》2003,18(8):955-958
We describe the pattern and progression of atrophy delineated using fluid registration of serial magnetic resonance imaging scans in a case of multiple system atrophy (MSA). The in vivo findings were consistent with those found at postmortem, including significant supratentorial atrophy concurrent with an unusual degree of cognitive impairment for MSA. 相似文献
55.
56.
57.
58.
59.
D A Gremse K J Peevy N Simon H J Wiseman 《Journal of pediatric gastroenterology and nutrition》1987,6(6):977-979
Patients with clinical signs of alpha 1-antitrypsin deficiency in the neonatal period usually present with prolonged obstructive jaundice. We report a patient with alpha 1-antitrypsin deficiency who presented with gallbladder enlargement in the neonatal period. This gallbladder enlargement may be due to cystic duct hypoplasia or atresia, which has been reported in association with alpha 1-antitrypsin deficiency. The diagnosis of alpha 1-antitrypsin deficiency should be considered in neonates with gallbladder enlargement and prolonged obstructive jaundice. 相似文献
60.
Jerome B. Simon 《Cancer metastasis reviews》1987,6(3):397-411
Testing feces for occult blood is widely recommended as a means of detecting subclinical colorectal tumors. Guaiac tests such as Hemoccult® are the most widely used, but chemical sensitivity is relatively low and the tests are affected by dietary peroxidases, the state of fecal hydration, and certain drugs. The newly devised HemoQuant® and immunologic techniques appear more sensitive and specific, but they require further evaluation before widespread clinical usage can be recommended.Occult blood screening has both merits and weaknesses. Testing does uncover subclinical colorectal cancer, often at a relatively early stage, but whether this actually improves the prognosis remains to be proven. Benign neoplastic polyps are also detected, although it is debatable whether this is a valid rationale for screening. Test sensitivity for malignancy varies from good to moderate, but is poor for benign polyps. Specificity is usually around 97%–98%, yet the predictive value of a positive test for cancer is only about 10%: hence most test-positive individuals are needlessly subjected to invasive colonic investigations. Reported figures on public compliance with occult blood testing vary widely from excellent to poor. Published costs of screening are usually quite low, but these overlook important indirect and hidden expenses and are therefore misleading.On balance, the problems of occult blood testing currently appear to outweight the merits. This could change, however, with the newer testing techniques and with awaited mortality data from controlled clinical trials now underway. 相似文献