Electron microscopy in the differential diagnosis and prognostic evaluation of muscle tissue tumors

The ultrastructure of striated and smooth muscle tumors of man was studied. A set of features indicating the histological origin of these tumors was established. The most informative feature for tumors of both groups is the presence of fragments of specific microfibrillar apparatus. An analysis of the extent of its development in the cell cytoplasm showed that this feature adequately reflects the tumor cataplasia. Thus, for rhabdomyosarcomas it was considered to be expedient to distinguish three groups according to the degree of the involvement of the myofibrillar apparatus (fibrillar, filamentous, and poorly differentiated types) which may be important for the prognostic evaluation of these tumors. Similar relationships were found with smooth muscle tumors. It is concluded that electron microscopy may be used successfully for differential diagnosis and determination of the degree of cataplasia of human muscle neoplasias.     

Morphometric analysis of ultrastructure of human synovioma cells]

Under examination were two gigantic-cell benign synoviomas and seven synovial sarcomas, including two metastatic tumors. The most specific ultrastructural criterion allowing a judgement of the degree of malignancy of the neoplasm under study is a parameter characterizing the predominance of ergastoplasmic protein synthesis over polyribosomal one.     

Wirkungen des Streptolysin O auf bedingte Reflexe

Zusammenfassung 1. Bei 20 Ratten wurde ein Stereotyp von bedingten Futterreflexen ausgearbeitet.2. Dosen von Streptolysin O und Typhustoxin, welche das Verhalten der Tiere noch nicht verändern, verursachen schon teilweise oder komplette Hemmung der positiven bedingten Reflexe.3. Nach wiederholter Applikation eines Giftes werden die Tiere gegen das Toxin resistent und reagieren nicht mehr mit Veränderungen der bedingten Reflexe.4. Tiere, die nicht mehr auf Streptolysin O reagieren, sind auch für Typhustoxin unempfindlich und umgekehrt.Mit 2 Textabbildungen