全文获取类型
收费全文 | 8682篇 |
免费 | 391篇 |
国内免费 | 62篇 |
专业分类
耳鼻咽喉 | 89篇 |
儿科学 | 86篇 |
妇产科学 | 71篇 |
基础医学 | 1015篇 |
口腔科学 | 285篇 |
临床医学 | 718篇 |
内科学 | 1858篇 |
皮肤病学 | 277篇 |
神经病学 | 560篇 |
特种医学 | 463篇 |
外科学 | 1629篇 |
综合类 | 51篇 |
一般理论 | 1篇 |
预防医学 | 395篇 |
眼科学 | 79篇 |
药学 | 694篇 |
中国医学 | 29篇 |
肿瘤学 | 835篇 |
出版年
2022年 | 73篇 |
2021年 | 157篇 |
2020年 | 96篇 |
2019年 | 123篇 |
2018年 | 166篇 |
2017年 | 115篇 |
2016年 | 147篇 |
2015年 | 148篇 |
2014年 | 194篇 |
2013年 | 235篇 |
2012年 | 398篇 |
2011年 | 464篇 |
2010年 | 257篇 |
2009年 | 184篇 |
2008年 | 358篇 |
2007年 | 388篇 |
2006年 | 375篇 |
2005年 | 362篇 |
2004年 | 360篇 |
2003年 | 360篇 |
2002年 | 323篇 |
2001年 | 296篇 |
2000年 | 313篇 |
1999年 | 300篇 |
1998年 | 129篇 |
1997年 | 70篇 |
1996年 | 67篇 |
1995年 | 79篇 |
1994年 | 65篇 |
1993年 | 49篇 |
1992年 | 217篇 |
1991年 | 197篇 |
1990年 | 218篇 |
1989年 | 218篇 |
1988年 | 172篇 |
1987年 | 192篇 |
1986年 | 160篇 |
1985年 | 155篇 |
1984年 | 101篇 |
1983年 | 82篇 |
1982年 | 39篇 |
1981年 | 50篇 |
1979年 | 94篇 |
1978年 | 42篇 |
1977年 | 52篇 |
1974年 | 47篇 |
1972年 | 40篇 |
1971年 | 40篇 |
1969年 | 45篇 |
1968年 | 40篇 |
排序方式: 共有9135条查询结果,搜索用时 265 毫秒
11.
Hiroshi Morita MD Douglas P. Zipes MD Shiho T. Morita MD Jiashin Wu PhD 《Heart rhythm》2007,4(1):66-74
BACKGROUND: The Brugada syndrome is characterized by ST-segment elevation on the ECG, especially in the right precordial leads sensitive to the right ventricular outflow tract (RVOT). OBJECTIVES: The purpose of this study was to evaluate the hypothesis that right ventricular electrophysiologic heterogeneity caused arrhythmogenicity in the Brugada syndrome. METHODS: Action potentials (APs) were mapped on the epicardium of 14 RVOT preparations and on the transmural surfaces of 15 pairs of RVOT and right ventricular anteroinferior (RVAI) preparations isolated from canine hearts. Brugada ECG and arrhythmias were induced with pilsicainide (2.5-12.5 micromol/L), pinacidil (1.25-12.5 micromol/L), and terfenadine (2.0 micromol/L). RESULTS: Low doses of drugs elevated the J-ST segment and induced APs with both short and long action potential durations (APDs) in contiguous RVOT epicardial regions. In addition, APs in the RVOT had a larger phase 1 notch and longer APD than in RVAI. The longest APDs were in the epicardium in RVOT but in the endocardium in RVAI regions. High doses of drugs eliminated the phase 2 dome of the AP and abbreviated APDs in the epicardium but not in endocardium and reduced the epicardial heterogeneity of APs but increased the transmural gradient of APD in 14 (93%) of the RVOT preparations. In contrast, abbreviations of epicardial APDs occurred in only 4 (27%) of the RVAI preparations. Ventricular tachycardia occurred more frequently in the RVOT (47%) than in paired RVAI preparations (7%). Blocking the transient outward current reduced the heterogeneity of APs and eliminated arrhythmogenicity in all preparations. CONCLUSION: Compared with the RVAI region, the RVOT has greater electrophysiologic heterogeneity that contributes to arrhythmogenicity in this model of Brugada syndrome. 相似文献
12.
Roberto Civitelli M.D. Eturo Ogata Louis V. Avioli Gary Stein Samuel Edelstein John A. Eisman Yasuho Nishii Hajime Orimo Jane Lian Takuo Fujita Yasufumi Hayashi Shigeaki Kato Tadashi Kobayashi Hirotoshi Morii Rikushi Morita Toshitaka Nakamura Yoshiki Seino Masataka Shiraki Tatsuo Suda Naoyuki Takahashi Hideaki Takahashi Tastuhiko Tanisawa Akifumi Tokita 《Calcified tissue international》1995,57(6):409-414
13.
We report a patient with graft versus host disease (GVHD) with mixed chimerism (MC). The patient had chronic myelogenous leukemia and received bone marrow transplantation (BMT) from his elder sister. Eighty days after BMT, erythematous lesions appeared on his chest. Histological examination from the skin lesion revealed lymphocytic infiltration into the upper dermis. Eosinophilic necrotic keratinocytes were scattered through the epidermis. Liquefaction degeneration was also recognized. Sicca syndrome appeared from 110 days after BMT. Detection of host origin Y-chromosome-specific DNA by polymerase chain reaction (PCR) method in bone marrow and peripheral blood showed that all bone marrow samples obtained 6 months from BMT were positive for Y-specific DNA, while peripheral blood became positive in the 60th month after BMT. The host origin normal karyotype (46,XY) in the bone marrow samples was identified for the first time in the 60th month after BMT. These results indicate that host-origin hematopoietic cells survived after BMT. 相似文献
14.
15.
K Kondoh S Sasaki T Oku S Minohara S Hasegawa Y Sawada M Morita A Takeuchi 《Kyobu geka. The Japanese journal of thoracic surgery》1992,45(7):565-9; discussion 569-72
In six hundred and six consecutive patients undergoing coronary artery bypass grafting (CABG) within the past 17 years (May 1974 to March 1991), repeated CABG were performed on 10 patients (1.65%). The main reasons for repeated CABG were graft failure (GF) in 8, progression of native disease (NP) in 5 and incomplete revascularization (IR) in 3 patients. The incidence of GF was high either within a half year or around 5 years after CABG. Although all patients survived from reoperation, four patients continued to have mild angina pectoris. When the recurrence of angina is noted after CABG, coronary arteriography and if necessary PTCA should be done as soon as possible. If a second surgery is inevitable, maximum utilization of arterial graft and accomplishment of complete revascularization are emphasized. 相似文献
16.
Electron-microscopic and immunohistochemical study of beta-2-microglobulin-related amyloidosis. 总被引:1,自引:0,他引:1
beta 2-Microglobulin (beta 2-MG)-related amyloidosis has been reported as a complication in long-term hemodialysis patients. We observed beta 2-MG amyloid deposits in synovial sheaths, bone cysts and gastric mucosa. They showed unique ultrastructural features, that is bundles or nodules consisting of curved or linear amyloid fibrils, associated with various cell reactions. The electron-microscopic histochemical study showed that they strongly stained with periodic acid-silver methenamine stain. A similar phenomenon was noticed in the spicules or bundles of amyloid fibrils in primary and secondary renal amyloidosis. With the cationic reagent toluidine blue 0, proteoglycan-like structures were observed around amyloid bundles and nodules, but not on each fibrils. Based on these results, we postulate that there is a close relationship between ultrastructural features and histochemical characteristics in beta 2-MG amyloid fibrils. 相似文献
17.
18.
19.
Comparison of characteristics of esophageal squamous cell carcinoma associated with head and neck cancer and those with gastric cancer 总被引:3,自引:0,他引:3
H Kuwano M Morita S Tsutsui Y Kido M Mori K Sugimachi 《Journal of surgical oncology》1991,46(2):107-109
In ongoing reviews of 339 patients with surgically treated primary squamous cell carcinoma, there were 19 (5.6%) with concurrent gastric cancer and 11 (3.2%) with head and neck cancer. The incidences of intra-esophageal multiple occurrence of esophageal cancer are 27.3% and 26.3% in those with associated head and neck cancer and gastric cancer, respectively, and higher than 7.1% in those without such a concurrent cancer. There was no difference in the clinicopathological characteristics of those with concurrent head and neck and gastric cancers, except for the higher incidence of metachronous occurrence in the former. These findings suggest that, in cases of esophageal cancer associated with concurrent head and neck cancer and gastric cancer, intraesophageal multiplicity of the esophageal carcinoma is frequent and that preoperative serial evaluations is most important to design treatment and estimate the prognosis. 相似文献
20.