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排序方式: 共有9093条查询结果,搜索用时 46 毫秒
21.
A R Vadiee E J Shannon T P Gillis R N Mshana R C Hastings 《International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association》1988,56(3):422-427
The kinetics of antibody responses of Mycobacterium leprae-infected armadillos to phenolic glycolipid-I (PGL-I) were studied by means of ELISA. The levels of both IgG and IgM antibodies to PGL-I increased with time. Some animals were less susceptible to disseminations of M. leprae infection and lived longer than others. These animals had high absorbance values (greater than 0.7) for IgG anti-PGL-I compared to more susceptible armadillos that had lower absorbance values for IgG anti-PGL-I. 相似文献
22.
Downregulation of adenylylcyclase types V and VI mRNA levels in pacing-induced heart failure in dogs. 总被引:2,自引:0,他引:2
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Y Ishikawa S Sorota K Kiuchi R P Shannon K Komamura S Katsushika D E Vatner S F Vatner C J Homcy 《The Journal of clinical investigation》1994,93(5):2224-2229
We have shown that the heart expresses two distinct forms of adenylylcyclase mRNA, types V and VI. In this study we have characterized the expression of these two mRNA species in heart failure generated by overdrive pacing at a rate of 240 beats/min. After 4 wk, left ventricular end-diastolic pressure and heart rate increased significantly with the appearance of signs of heart failure, i.e., edema, ascites, and exercise intolerance. Basal as well as forskolin-stimulated adenylylcyclase activities decreased significantly, which was accompanied by a reduction in the steady state mRNA levels of adenylylcyclase types V and VI. These data suggest that in this model of cardiomyopathy, the downregulation of adenylylcyclase catalytic activity results, at least in part, from a reduction in the steady state levels of types V and VI adenylylcyclase mRNA levels. 相似文献
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Introduction Medication errors are a preventable cause of patient injury. In May 2003, as a result of a joint initiative by the Royal College
of Anaesthetists, the Association of Anaesthetists of Great Britain and Ireland, the Intercollegiate Faculty of Accident and
Emergency Medicine and the Intensive Care Society, a new colour code chart for syringe labelling was introduced. The introduction
of the new system has not been uniform in the Irish Republic with no national guidelines or time scale in place.
Methods A questionnaire was administered to doctors working in Anaesthesia in two Dublin teaching hospitals.
Results As much as 23% had administered an incorrect medication and 53% admitted to a near miss as a result of the introduction of
the new label.
Discussion Future action should focus on practical, common sense interventions including techniques such as those that reduce reliance
on memory, standardization, the use of protocols and checklists, and the elimination of look-alike products. 相似文献
27.
Bradley J Katz John R Burroughs Richard L Anderson Shannon Bownds John D McCann 《Movement disorders》2007,22(2):231-234
We present a patient with a facial movement disorder that has characteristics of both blepharospasm and bilateral asynchronous hemifacial spasm. Because of the increased incidence of blepharospasm in patients with hemifacial spasm, our patient's clinical presentation is probably not a chance occurrence, but rather a manifestation of some predisposition for these two movement disorders. This unusual constellation of signs and symptoms challenges the current diagnostic criteria and suggests that some of these facial movement disorders may lie on a spectrum, rather than represent distinct entities. 相似文献
28.
R L Shannon J Y Ro D J Grignon N G Ordó?ez D E Johnson B Mackay B Têtu A G Ayala 《Cancer》1992,69(11):2676-2682
Sarcomatoid carcinoma of the prostate is a rare tumor that can be difficult to distinguish from a true sarcoma. The authors report 12 patients in whom the typical light microscopic appearance of prostatic adenocarcinoma was accompanied by the appearance of spindled or pleomorphic sarcomatoid areas within the same specimen or in subsequent accessions. Immunostaining or electron microscopic study demonstrated epithelial differentiation within the sarcomatoid area(s) in 6 of the 11 patients in whom special studies were performed. All nine patients for whom follow-up data were available died of disease within 3 to 48 months (median time until death, 12.0 months) after the appearance of the sarcomatoid carcinoma, and the clinical course in each instance was characterized by aggressive local recurrence. Our experience confirms that sarcomatoid carcinoma of the prostate is an aggressive variant of prostatic adenocarcinoma. 相似文献
29.
M Denison C Shannon D Rafter 《Australasian physical & engineering sciences in medicine / supported by the Australasian College of Physical Scientists in Medicine and the Australasian Association of Physical Sciences in Medicine》1992,15(1):42-44
The assessment of mechanical ventilator performance is a complex task requiring measurement of a number of different transducers under a variety of conditions. The use of dedicated testing equipment can alleviate the complexity of the experimental apparatus. This paper assesses the accuracy and versatility of the Biotek VT-1 and VT-2 dedicated ventilator testers. Results show that the testers perform within the manufacturer's specifications and have the required flexibility to be used in investigating faults reported with ventilators. 相似文献
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