全文获取类型
收费全文 | 181篇 |
免费 | 45篇 |
国内免费 | 1篇 |
专业分类
儿科学 | 17篇 |
妇产科学 | 1篇 |
基础医学 | 36篇 |
口腔科学 | 4篇 |
临床医学 | 39篇 |
内科学 | 42篇 |
皮肤病学 | 4篇 |
神经病学 | 7篇 |
特种医学 | 13篇 |
外科学 | 7篇 |
综合类 | 10篇 |
预防医学 | 26篇 |
眼科学 | 1篇 |
药学 | 4篇 |
肿瘤学 | 16篇 |
出版年
2021年 | 3篇 |
2020年 | 3篇 |
2019年 | 2篇 |
2018年 | 4篇 |
2017年 | 5篇 |
2016年 | 3篇 |
2015年 | 3篇 |
2014年 | 6篇 |
2013年 | 11篇 |
2012年 | 3篇 |
2011年 | 6篇 |
2010年 | 8篇 |
2009年 | 8篇 |
2008年 | 9篇 |
2007年 | 3篇 |
2006年 | 4篇 |
2004年 | 6篇 |
2003年 | 2篇 |
2002年 | 3篇 |
2001年 | 2篇 |
1999年 | 6篇 |
1998年 | 5篇 |
1997年 | 7篇 |
1995年 | 3篇 |
1993年 | 6篇 |
1992年 | 2篇 |
1991年 | 4篇 |
1990年 | 5篇 |
1989年 | 5篇 |
1988年 | 5篇 |
1987年 | 5篇 |
1986年 | 6篇 |
1985年 | 3篇 |
1984年 | 4篇 |
1983年 | 4篇 |
1982年 | 8篇 |
1981年 | 3篇 |
1979年 | 4篇 |
1978年 | 6篇 |
1977年 | 5篇 |
1976年 | 5篇 |
1975年 | 5篇 |
1974年 | 2篇 |
1973年 | 2篇 |
1972年 | 2篇 |
1971年 | 2篇 |
1970年 | 2篇 |
1966年 | 3篇 |
1965年 | 3篇 |
1940年 | 1篇 |
排序方式: 共有227条查询结果,搜索用时 15 毫秒
91.
92.
93.
Vaccination of yeast sensitive individuals: review of safety data in the US vaccine adverse event reporting system (VAERS) 总被引:4,自引:0,他引:4
The preparation of recombinant hepatitis B vaccines involves using cellular cultures of Saccharomyces cerevisiae, otherwise known as baker's yeast. Prior to vaccine licensure, clinical trials were performed to address whether residual yeast proteins in the vaccines could induce anaphylaxis, including testing for IgE anti-yeast antibody levels. 1-2% of subjects had anti-yeast IgE antibodies before immunization, but demonstrated no significant rise in IgE after HBV. We searched reports in the Vaccine Adverse Event Reporting System (VAERS) for those that mentioned a history of allergy to yeast and then reviewed the adverse events described in these reports for potential anaphylactic reactions. Probable anaphylaxis was defined as the presence of one or more dermatologic symptoms and one or more respiratory, gastrointestinal, or cardiovascular symptoms with onset within 4 h of Hepatitis B vaccination. Possible anaphylaxis was defined in one of two ways: (1) cases that described dermatologic or respiratory symptoms (but not both) occurring within 4h of vaccination; or (2) cases that described one or more dermatologic and/or respiratory symptoms occurring 4-12 h post vaccination. Among the 107 reports of pre-existing "yeast allergies," 11 reports described probable or possible anaphylaxis after HBV. Four additional cases were described after other vaccines. The majority of vaccinees who met the case definitions and had a history of yeast allergies were female, ages ranged from 10 to 64, and symptom onset ranged from 15 min to 5 h after vaccination. No deaths were reported. The small number of reports to VAERS may be partly due to health care professionals observing current contraindications by not vaccinating yeast sensitive individuals. Nevertheless, yeast associated anaphylaxis after HBV in sensitized patients appears to be a rare event. 相似文献
94.
B. A. Body R. A. Fromtling S. Shadomy H. J. Shadomy 《European journal of clinical microbiology & infectious diseases》1983,2(3):230-234
The antibacterial activity of norfloxacin, an organic acid structurally related to nalidixic acid, was compared with that of the oral cephalosporins cefaclor and cephalexin, and with that of nalidixic acid, cinoxacin, amikacin, ampicillin, trimethoprim alone and the combination of trimethoprim and sulfamethoxazole. Agar dilution studies were performed with a total of 398 clinical isolates of gram-negative bacteria, Norfloxacin was found to be the most active drug studied against each of the different groups of organisms tested. MIC90 values for norfloxacin were as follows:Citrobacter spp., 2μg/ml;Enterobacter spp., 0.13μg/ml;Escherichia coli, 0.06μg/ml;Klebsiella spp., 0.13μg/ml;Proteus spp., 0.06μg/ml;Salmonella spp., 1μg/ml;Serratia spp., 0.13μg/ml; andPseudomonas spp., 2μg/ml. MIC90 values for the other drugs were 4μg/ml or greater and many organisms were totally resistant to one or more of the other drugs (MIC > 128μg/ml). Cross resistance between norfloxacin and the related drugs nalidixic acid and cinoxacin was not observed. 相似文献
95.
96.
97.
Sergio N Nemer Carmen SV Barbas Jefferson B Caldeira Thiago C Cárias Ricardo G Santos Luiz C Almeida Leandro M Azeredo Rosângela A Noé Bruno S Guimarães Paulo C Souza 《Critical care (London, England)》2009,13(5):R152
Introduction
Indexes predicting weaning outcome are frequently inaccurate. We developed a new integrative weaning index aimed at improving the accuracy of the traditional indexes. 相似文献98.
99.
Rajesh Kumar Hemant Gupta Anil Jadhav SV Khadilkar 《Indian journal of dermatology》2013,58(4):328-Aug;58(4):328
A 74-year-old man was presented with fever, bilateral throbbing temporoparietal headache, jaw claudication, and bilateral loss of vision. On examination, he had bilateral scalp necrosis with impending necrosis of lip and tongue. Temporal artery biopsy was done, and it was compatible with active temporal arteritis. This is one of the rare presentations of giant cell arteritis where there is simultaneous necrosis of scalp, lip, and tongue, and to the best of our knowledge, it is the first case reported from India. 相似文献
100.
de Matos GF Stanzani F Passos RH Fontana MF Albaladejo R Caserta RE Santos DC Borges JB Amato MB Barbas CS 《Critical care (London, England)》2012,16(1):R4