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991.
Brucella infection in a child with progressive familial intrahepatic cholestasis type 2 who had undergone liver transplantation 下载免费PDF全文
Murat Sutcu Damla Gokceer Hacer Akturk Ayper Somer Selda Hancerli Torun Mustafa Serdar Cantez Ozlem Durmaz Nuran Salman 《Pediatric transplantation》2015,19(6):E146-E148
Brucellosis is considered the most widespread zoonosis in the world. In endemic regions of brucellosis, childhood brucellosis includes up to one‐third of all cases of human brucellosis. Brucellosis constitutes a public health problem in Turkey. A boy aged 12 yr who had PFIC2 had undergone deceased‐donor liver transplantation in 2008 at the age of seven. The boy presented with fatigue, fever, and pain in the right leg and hip and was admitted to the hospital. Brucella melitensis grew in the blood culture, and the SAT was positive at a titer of 1:640. The patient was treated with oral doxycycline and rifampicin for eight wk. After treatment, the patient recovered and his blood cultures became negative. The patient's mother also had a high Brucella agglutination titer of 1:320 positive and was treated in the internal medicine department with spiramycin and doxycycline. Brucella infection should be suspected in liver transplant recipients with fever of unknown origin, especially in recipients who live in an endemic area. 相似文献
992.
The aim of this study was to determine the incidence and role of c-erbB-2 overexpression as a predictive/prognostic marker
in small-cell lung carcinoma (SCLC). We performed a retrospective study on subjects with a biopsy-proven diagnosis of SCLC.
A chart review for demographic and clinical data was performed on patients with SCLC diagnosed between 1998 and 2004. c-erbB-2
overexpression was evaluated using immunohistochemistry performed on archival paraffin-embedded specimens. Sixty-seven patients
with SCLC were identified (6 females, 61 males; median age- 56.5 yr, range-34–75) all of whom had adequate tissue specimens
available for c-erB-2 testing. Of the 67 specimens, 12 (17.9%) showed c-erbB-2 overexpression. Seventy-five of the cases were
positive for c-erbB-2, had extensive disease. The median overall survival of patients with SCLC whose tumors were positive
and negative for c-erbB-2 were 8 ± 0.9 months (95%CI 6.3–9.7) and 11 ± 1.5 months (95%CI 8.0–14.0), respectively. c-erbB-2
overexpression detected using immunohistochemistry is observed in 17.9% of patients with SCLC and has statistically significant
prognostic value. Our findings suggest that c-erbB-2 may be a potential target for site-specific immunotherapy in SCLC. Considering
one technique examined, further molecular investigation is needed to confirm these preliminary findings. 相似文献
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GliomaPredict: a clinically useful tool for assigning glioma patients to specific molecular subtypes
Aiguo Li Serdar Bozdag Yuri Kotliarov Howard A Fine 《BMC medical informatics and decision making》2010,10(1):38
Background
Advances in generating genome-wide gene expression data have accelerated the development of molecular-based tumor classification systems. Tools that allow the translation of such molecular classification schemas from research into clinical applications are still missing in the emerging era of personalized medicine. 相似文献995.
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Rahman Şenocak Ali Kağan Coşkun Şahin Kaymak Yusuf Serdar Sakin 《Arab Journal Of Gastroenterology》2018,19(2):88-90
Although endoscopic retrograde cholangio-pancreatography (ERCP) is considered a safe procedure, it is associated with complications such as pancreatitis, bleeding and perforation of the bile duct, pancreatic duct and duodenum. In recent years, successful conservative treatment in selected patients with complications have increased. We present a case with successful conservative treatment of rare injury (type 3) developing after ERCP. 相似文献
999.
Serdar Demir Abdulkadir Uslu Ahmet Guner Sabahattin Gunduz Muzaffer Kahyaoglu Ayhan Kup Mehmet Celik Ozge Akgun Munevver Sarı Taylan Akgun 《Journal of electrocardiology》2018,51(3):409-412
Malignant ventricular arrhythmias are challenging to manage, requiring a multidisciplinary approach. The mechanism, which triggers ventricular fibrillation (VF) associated with ventricular extrasystoles has not been clarified yet, however, abolishing ventricular extrasystoles may stop ventricular fibrillation in these patients. By this case presentation, we aimed to present a successful treatment of an electrical storm (ES), which developed after an acute myocardial infarction, by catheter ablation. 相似文献