全文获取类型
收费全文 | 2478篇 |
免费 | 156篇 |
国内免费 | 15篇 |
专业分类
耳鼻咽喉 | 27篇 |
儿科学 | 201篇 |
妇产科学 | 78篇 |
基础医学 | 213篇 |
口腔科学 | 98篇 |
临床医学 | 230篇 |
内科学 | 564篇 |
皮肤病学 | 54篇 |
神经病学 | 174篇 |
特种医学 | 72篇 |
外科学 | 308篇 |
综合类 | 39篇 |
预防医学 | 151篇 |
眼科学 | 85篇 |
药学 | 161篇 |
中国医学 | 13篇 |
肿瘤学 | 181篇 |
出版年
2024年 | 6篇 |
2023年 | 45篇 |
2022年 | 112篇 |
2021年 | 170篇 |
2020年 | 90篇 |
2019年 | 103篇 |
2018年 | 117篇 |
2017年 | 78篇 |
2016年 | 85篇 |
2015年 | 88篇 |
2014年 | 121篇 |
2013年 | 141篇 |
2012年 | 183篇 |
2011年 | 158篇 |
2010年 | 91篇 |
2009年 | 64篇 |
2008年 | 148篇 |
2007年 | 127篇 |
2006年 | 110篇 |
2005年 | 111篇 |
2004年 | 96篇 |
2003年 | 90篇 |
2002年 | 82篇 |
2001年 | 33篇 |
2000年 | 33篇 |
1999年 | 26篇 |
1998年 | 14篇 |
1997年 | 6篇 |
1996年 | 10篇 |
1995年 | 9篇 |
1994年 | 8篇 |
1993年 | 7篇 |
1992年 | 5篇 |
1991年 | 7篇 |
1990年 | 8篇 |
1989年 | 11篇 |
1988年 | 5篇 |
1987年 | 6篇 |
1986年 | 9篇 |
1985年 | 2篇 |
1979年 | 2篇 |
1978年 | 2篇 |
1977年 | 3篇 |
1975年 | 2篇 |
1974年 | 4篇 |
1973年 | 4篇 |
1970年 | 4篇 |
1968年 | 2篇 |
1936年 | 2篇 |
1910年 | 2篇 |
排序方式: 共有2649条查询结果,搜索用时 15 毫秒
61.
Yoshinori Tanabe Takayuki Ishida Hidetoshi Eto Tatsuhiro Sera Yuki Emoto Mototsugu Shimokawa 《Medical Dosimetry》2021,46(1):e5-e10
This study aimed to evaluate the optimal method for planning computed tomography (CT) for prostate cancer radiotherapy to avoid a dose difference of ≥3% between the actual and planned treatments using multiple acquisition planning CT (MPCT). We calculated the 3-dimensional (3D) displacement error between the pelvic bone and matching fiducial marker on MPCT and cone-beam CT scans of 25 patients who underwent prostate volumetric-modulated arc therapy for prostate cancer. The correlation of the 3D displacement error and the dose difference between planned and actual treatments was calculated using least squares second-order polynomial model. The 3D displacement error showed a moderate correlation with differences between planned and accumulated treatment doses (r = 0.587, p < 0.0001). Moreover, the improvement rate of the minimum 3D displacement error showed a strong correlation with the relative error between each MPCT image (r = 0.793, p < 0.0001). Significant differences were observed between planned and actual treatment doses (p < 0.0001) in the relative 3D displacement errors of <1 mm, 1 to 3 mm, and >3 mm. The 3D displacement error on MPCT (as the selection estimation index for optimal planning CT) is useful for monitoring patient-specific intensity-modulated radiation therapy quality assurance. This new method allows to estimate dose differences from the planned dose before commencing treatment, thereby ensuring high-quality therapy. As radiotherapy quality is critical for patient outcome, these findings may contribute to better management of prostate cancer. 相似文献
62.
Ozturk Buket Caliskaner Atahan Ersan Gencer Aysegul Harbiyeli Deniz Ongel Karabul Emine Mazıcan Nejdiye Toplutas Kubra Nur Acar Hazal Cansu Sager Sait Gemicioglu Bilun Borekci Sermin 《Annals of nuclear medicine》2021,35(10):1117-1125
Annals of Nuclear Medicine - Pulmonary embolism is a severe source of mortality and morbidity in patients with severe and critical coronavirus disease 2019. It is not yet clear whether the tendency... 相似文献
63.
Clinical Oral Investigations - This in vitro study aimed to investigate the color changes of the bracket-bonded tooth surfaces after the use of 4 different mouthwashes. A total of 100 human... 相似文献
64.
65.
66.
Fevzi Altuntas Naim Ata Tugce Nur Yigenoglu Semih Bascı Mehmet Sinan Dal Serdal Korkmaz Sinem Namdaroglu Abdulkadir Basturk Tuba Hacıbekiroglu Mehmet Hilmi Dogu İlhami Berber Kursat Dal Kerem Kınık İbrahim Haznedaroglu Fatma Meriç Yılmaz İsa Kılıç Sinan Demircioğlu Alper Yosunkaya Osman Celik 《Transfusion and apheresis science》2021,60(1):102955
IntroductionPassive antibody therapy has been used to immunize vulnerable people against infectious agents. In this study, we aim to investigate the efficacy of convalescent plasma (CP) in the treatment of severe and critically ill patients diagnosed with COVID-19.MethodThe data of severe or critically ill COVID-19 patients who received anti-SARS-CoV-2 antibody-containing CP along with the antiviral treatment (n = 888) and an age-gender, comorbidity, and other COVID-19 treatments matched severe or critically ill COVID-19 patients at 1:1 ratio (n = 888) were analyzed retrospectively.ResultsDuration in the intensive care unit (ICU), the rate of mechanical ventilation (MV) support and vasopressor support were lower in CP group compared with the control group (p = 0.001, p = 0.02, p = 0.001, respectively). The case fatality rate (CFR) was 24.7 % in the CP group, and it was 27.7 % in the control group. Administration of CP 20 days after the COVID-19 diagnosis or COVID-19 related symptoms were associated with a higher rate of MV support compared with the first 3 interval groups (≤5 days, 6?10 days, 11?15 days) (p=0.001).ConclusionCP therapy seems to be effective for a better course of COVID-19 in severe and critically ill patients. 相似文献
67.
Tolga Kurt Ahmet Vural Ahmet Temiz Ersan Ozbudak Ali Umit Yener Suzan Sacar Mustafa Sacar 《Brazilian Journal Of Cardiovascular Surgery》2015,30(5):538-543
OBJECTIVE
In the post-sternotomy mediastinitis patients, Staphylococcus aureus is the pathogenic microorganism encountered most often. In our study, we aimed to determine the efficacy of antibiotic treatment with vancomycin and tigecycline, alone or in combination with hyperbaric oxygen treatment, on bacterial elimination in experimental S. aureus mediastinitis.METHODS
Forty-nine adult female Wistar rats were used. They were randomly divided into seven groups, as follows: non-contaminated, contaminated control, vancomycin, tigecycline, hyperbaric oxygen, hyperbaric oxygen + vancomycin and hyperbaric oxygen + tigecycline. The vancomycin rat group received 10 mg/kg/day of vancomycin twice a day through intramuscular injection. The tigecycline group rats received 7 mg/kg/day of tigecycline twice a day through intraperitoneal injection. The hyperbaric oxygen group underwent 90 min sessions of 100% oxygen at 2.5 atm pressure. Treatment continued for 7 days. Twelve hours after the end of treatment, tissue samples were obtained from the upper part of the sternum for bacterial count assessment.RESULTS
When the quantitative bacterial counts of the untreated contaminated group were compared with those of the treated groups, a significant decrease was observed. However, comparing the antibiotic groups with the same antibiotic combined with hyperbaric oxygen, there was a significant reduction in microorganisms identified (P<0.05). Comparing hyperbaric oxygen used alone with the vancomycin and tigecycline groups, it was seen that the effect was not significant (P<0.05).CONCLUSION
We believe that the combination of hyperbaric oxygen with antibiotics had a significant effect on mediastinitis resulting from methicillin-resistant Staphylococcus aureus. Methicillin-resistant Staphylococcus aureus mediastinitis can be treated without requiring a multidrug combination, thereby reducing the medication dose and concomitantly decreasing the side effects. 相似文献68.
69.
The evaluation of flap growth and long‐term results of pediatric mandible reconstructions using free fibular flaps
下载免费PDF全文
![点击此处可从《Microsurgery》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Gökhan Temiz M.D. Ufuk Bilkay M.D. Yiğit Özer Tiftikçioğlu M.D. Candan Tevfik Mezili M.D. Ecmel Songür M.D. 《Microsurgery》2015,35(4):253-261
Currently, the free fibular flap is well accepted as the first choice for mandibular reconstruction. Achieving functional results in pediatric patients requires a different approach than that employed for mature patients. Because the pediatric craniofacial skeleton continues to grow, reconstruction is more challenging, and the long‐term results can be different from those of adult patients. In this study, we sought to measure flap growth objectively in our series. Ten pediatric patients who underwent reconstruction with free fibular flaps were retrospectively reviewed. Flap growth was evaluated by comparing the intraoperative photographs with photographs of the control panoramic mandibular radiographs taken using photo‐anthropometric techniques. The measurements were converted to proportionality indices (PI), and these indices were compared. Subsequent complications and functional results were also evaluated. The mean patient age was 11.8 years, and the mean follow up was 57.7 months. The mean preoperative PI value was 10.74 ± 2.47. The mean postoperative PI value was 12.52 ± 2.34. The mean difference between the preoperative and postoperative PI values was ?1.78±0.53. These photo‐anthropometric data clearly illustrated the growth of the fibular flaps (P = 0.001). None of these patients exhibited nonunion of the fractures; however, one patient experienced a delayed union, one had chronic temporomandibular joint pain, and one had chronic temporomandibular joint luxation. In two patients, the inter‐incisive measurements were below the third percentile, and two additional patients had grade 2 eating abilities, which can be regarded as poor. All of the patients had symmetric mandibular contours. Free fibular flaps continue to grow in pediatric patients. This flap is a “workhorse” flap in children because it adapts to the craniofacial skeleton via its ability to grow, and this ability results in subsequent good cosmetic and functional results. © 2014 Wiley Periodicals, Inc. Microsurgery 35:253–261, 2015. 相似文献
70.