Growth of melanocytes in a skin equivalent model in vitro

We have developed a pigmented human skin equivalent by inserting a punch biopsy of human infant foreskin as a source of epidermis into a collagen lattice (dermal equivalent). Using a conventional epidermal culture medium and stimulation with UVB irradiation or 8-MOP + UVA treatment, melanocytes were found to grow out from the biopsy with the epidermal sheet. In this newly formed epidermis, melanocytes and keratinocytes were maintained in an architectural relationship similar to that present in vivo and melanocyte outgrowth could be quantitatively evaluated. Consequently, this pigmented human skin equivalent is a useful model for investigating the biology and photobiology of human skin pigmentation.     

"云娜"台风对人群伤害现状的流行病学研究

2004年8月12日晚20时“云娜”（rananim）台风在浙江省温岭市石塘镇登陆后给当地造成了严重的人员伤亡和经济损失。为了解本次台风造成伤害的流行特征,分析伤害原因,提供预防与控制对策,我们开展了现场流行病学调查,现将调查结果报告如下。     

抗凝治疗对慢性肺心病高凝状态的疗效观察

慢性肺心病急性加重期常伴有血液高凝状态,我科近年来在慢性肺心病急性加重期在常规治疗的基础上加用抗凝治疗,对肺心病伴高凝状态的病人进行临床观察,取得了良好的疗效,小结如下。