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Steiner E; Mueller PR; Hahn PF; Saini S; Simeone JF; Wittenberg J; Warshaw AL; Ferrucci JT Jr 《Radiology》1988,167(2):443-446
Twenty-five patients with grade D or E pancreatitis underwent percutaneous drainage. These patients required multiple computed tomography (CT) examinations, multiple catheter insertions, multiple catheter manipulations, and long-term catheter drainage. Eight of the 25 patients were successfully treated with catheter drainage alone. Sixteen underwent surgical drainage, ten after attempts at percutaneous drainage and six prior to radiologic drainage. Of the ten patients who had initial percutaneous drainage, only four were clinically improved from the drainage procedure alone. Although the fluid component of the abscess was often adequately drained in all ten patients, surgery was required to remove pieces of necrotic debris. Six patients who underwent surgical debridement had residual abscesses in the post-operative period and were all successfully treated with percutaneous drainage. One patient died from unrelated causes. Successful interventional management of patients with pancreatic abscesses requires intensive radiologic intervention and monitoring and may be better served by a combination of radiologic and surgical means. 相似文献
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Botulinum A Toxin Injected into the Gastric Wall for the Treatment of Class III Obesity: A Pilot Study 总被引:2,自引:2,他引:0
Júnior AC Savassi-Rocha PR Coelho LG Spósito MM Albuquerque W Diniz MT Paixão Ade M Garcia FD Lasmar LF 《Obesity surgery》2006,16(3):335-343
Background: Obesity represents a major public health problem in western countries. Initial studies suggest that injection
of botulinum A toxin (Btx-A) into the antropyloric region inhibits propulsive contractions of the antral pump, with delay
in gastric emptying, early satiety and weight loss. Methods: After approval by the University Ethics Committee, we prospectively
evaluated 12 patients with class III obesity divided into 4 groups of 3 patients each. In groups I and II, 200 U Btx-A were
injected into the antropyloric region at 8 and 16 sites, respectively. Groups III and IV received 300 U Btx-A into the antropyloric
region at 16 and 24 sites, respectively. Body weight and gastric emptying time (GET) of solids and semi-solids using 13C-octanoic acid breath test and 13C-acetic acid breath test, respectively, were determined before and after injection over a period of 12 weeks. Results: Pre-
and post-treatment body weight or solid and semi-solid GET did not differ significantly between groups (P>0.05). All patients reported a feeling of early satiety. No adverse effects related to BtxA or complications resulting from
the endoscopic procedure were observed. Conclusion: The injection of different doses of BtxA at different sites in the antropyloric
region of patients with class III obesity did not interfere significantly with the solid and semi-solid GET or body weight
of these individuals. However, early satiety was reported by all patients, the procedure was safe and no side-effects of the
treatment were observed. Further controlled studies involving different methodologies regarding dosage of Btx-A and sites
of injection are necessary. 相似文献
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Tinoco A El-Kadre L Aquiar L Tinoco R Savassi-Rocha P 《World journal of surgery》2011,35(10):2238-2244