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991.
Hideaki Miyamoto Hiroaki Ikematsu Satoshi Fujii Shozo Osera Tomoyuki Odagaki Yasuhiro Oono Tomonori Yano Atsushi Ochiai Yutaka Sasaki Kazuhiro Kaneko 《International journal of colorectal disease》2014,29(9):1069-1075
Purpose
Laterally spreading tumors (LST) have been recognized worldwide. The aim of our retrospective study was to evaluate the clinicopathological differences of LST arising in the colon and rectum.Methods
We investigated the clinical records of consecutive patients with LST that were endoscopically or surgically resected at our hospital between February 2006 and March 2011. LST were classified into three types: granular-homogenous (LST-GH), granular-nodular mixed (LST-GM), and nongranular (LST-NG) types. We also defined the hardly elevated flat lesion with a dilated pit pattern that occurs at the margins of LST as the “skirt.” The clinicopathological characteristics of the LST arising in the colon and rectum, including the presence of the skirt, were compared.Results
A total of 496 colorectal LST in 435 patients were examined. LST-GM was predominant in the rectum, whereas LST-NG was predominant in the colon (p?0.001). The mean tumor size was larger in the rectum (39.3?±?17.9 mm) than the colon (25.8?±?13.6 mm) (p?0.001). Low-grade dysplasia frequency was lower in the rectum than the colon (4 vs. 37 %, p?0.001). The skirt was identified in 15 lesions (3.0 %), with a higher incidence in the rectum than the colon (17 vs. 0.5 %, p?0.001). The skirt was found only in LST-GM.Conclusions
A greater proportion of LST-GM, greater mean size, and lower incidence of low-grade dysplasia were found in rectal LST. The skirt was a novel and unique finding, primarily observed in rectal LST-GM cases. 相似文献992.
993.
994.
Preoperative diagnosis of portal vein invasion in pancreatic head cancer: appropriate indications for concomitant portal vein resection
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![点击此处可从《Journal of hepato-biliary-pancreatic sciences》网站下载免费的PDF全文](/ch/ext_images/free.gif)
995.
Intestinal epithelial culture under an air‐liquid interface: a tool for studying human and mouse esophagi
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![点击此处可从《Diseases of the esophagus》网站下载免费的PDF全文](/ch/ext_images/free.gif)
T. Yokobori S. Suzuki T. Miyazaki M. Sohda M. Sakai N. Tanaka D. Ozawa K. Hara H. Honjo B. Altan M. Fukuchi H. Ishii M. Iwatsuki K. Sugimachi T. Sudo T. Iwaya N. Nishida K. Mimori H. Kuwano M. Mori 《Diseases of the esophagus》2016,29(7):843-847
This study investigated whether an intestinal epithelial culture method can be applied to mouse and human esophageal cultures. The esophagi harvested from 1‐day‐old mice and adult humans were maintained in collagen gels. A commercially available culture medium for human embryonic stem cells was used for the human esophageal culture. We discovered that the intestinal epithelial culture method can be successfully applied to both mouse and human esophageal cultures. The long‐term cultured esophageal organoids were rod‐like luminal structures lined with myofibroblasts. We discovered that regeneration of the esophageal mucosal surface can be almost completely achieved in vitro, and the advantage of this method is that organoid cultures may be generated using host‐derived fibroblasts as a niche. This method is a promising tool for mouse and human research in intestinal biology, carcinogenesis, and regenerative medicine. 相似文献
996.
Older Korean adults have lower physical function despite longer exercise times compared to their Japanese counterparts: A Japan‐Korea comparative study
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![点击此处可从《Geriatrics & Gerontology International》网站下载免费的PDF全文](/ch/ext_images/free.gif)
997.
Disseminated toxoplasmosis after hematopoietic stem cell transplantation showing unusual magnetic resonance images
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![点击此处可从《Transplant infectious disease》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Takahiro Tateno Masahiro Onozawa Junichi Hashiguchi Takashi Ishio Sayaka Yuzawa Satomi Matsuoka Mizuha Kosugi‐Kanaya Kohei Okada Souichi Shiratori Hideki Goto Taichi Kimura Junichi Sugita Masao Nakagawa Daigo Hashimoto Kaoru Kahata Katsuya Fujimoto Tomoyuki Endo Takeshi Kondo Shinya Tanaka Satoshi Hashino Takanori Teshima 《Transplant infectious disease》2017,19(4)
We herein report a patient who had disseminated toxoplasmosis after hematopoietic stem cell transplantation showing atypical clinical presentation and neuroimaging. Parkinsonism symptoms such as muscle rigidity, bradykinesia, tremor, and postural instability were initial manifestations. Magnetic resonance imaging showed diffuse symmetrical lesions of bilateral basal ganglia lacking ringed enhancement. Post‐mortem analysis revealed multiple tachyzoites of Toxoplasma gondii in the basal ganglia, mid brain, cerebellum, and cardiac muscle. 相似文献
998.
999.
Clinical impact of the presence of macrophages in endomyocardial biopsies of patients with dilated cardiomyopathy
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![点击此处可从《European journal of heart failure》网站下载免费的PDF全文](/ch/ext_images/free.gif)
1000.
Tips for anatomical hepatectomy for hepatocellular carcinoma by the Glissonean pedicle approach (with videos)
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![点击此处可从《Journal of hepato-biliary-pancreatic sciences》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Masakazu Yamamoto Satoshi Katagiri Shun‐ichi Ariizumi Yoshihito Kotera Yutaka Takahashi Hiroto Egawa 《Journal of hepato-biliary-pancreatic sciences》2014,21(8):E53-E56
Couinaud described three fundamental approaches at the hepatic hilus in liver surgery. The Glissonean pedicle approach at the hepatic hilus is one of these procedures and provides anatomical hepatectomy for hepatocellular carcinoma (HCC). The Glissonean pedicle approach was introduced by Couinaud and Takasaki in the early 1980s. The key of the Glissonean pedicle approach is clamping the pedicle first, secondly confirming the territory, which includes the HCC, and finally dissecting the liver parenchyma. This procedure prevents intrahepatic metastasis of HCC, which spreads along the portal vein and improves the overall survival after surgery. Another key feature is that we do not have to consider any variations of the vascular elements in the hepatoduodenal ligament under the hilar plate. This procedure allows an approach to the tertiary branches, which feed a smaller anatomical area than Couinaud's segment. We refer to this area as a cone unit of the liver. The procedure is also available in laparoscopic hepatectomy and provides new knowledge of the surgical anatomy, especially for small anatomical liver resection in the cirrhotic liver. 相似文献