全文获取类型
收费全文 | 513篇 |
免费 | 21篇 |
国内免费 | 20篇 |
专业分类
耳鼻咽喉 | 13篇 |
儿科学 | 32篇 |
妇产科学 | 6篇 |
基础医学 | 51篇 |
口腔科学 | 8篇 |
临床医学 | 52篇 |
内科学 | 118篇 |
皮肤病学 | 13篇 |
神经病学 | 45篇 |
特种医学 | 67篇 |
外科学 | 50篇 |
综合类 | 19篇 |
预防医学 | 26篇 |
眼科学 | 4篇 |
药学 | 26篇 |
中国医学 | 1篇 |
肿瘤学 | 23篇 |
出版年
2023年 | 3篇 |
2022年 | 6篇 |
2021年 | 10篇 |
2020年 | 11篇 |
2019年 | 9篇 |
2018年 | 18篇 |
2017年 | 11篇 |
2016年 | 16篇 |
2015年 | 22篇 |
2014年 | 20篇 |
2013年 | 28篇 |
2012年 | 26篇 |
2011年 | 20篇 |
2010年 | 15篇 |
2009年 | 22篇 |
2008年 | 17篇 |
2007年 | 27篇 |
2006年 | 14篇 |
2005年 | 11篇 |
2004年 | 6篇 |
2003年 | 8篇 |
2002年 | 12篇 |
2001年 | 12篇 |
2000年 | 5篇 |
1999年 | 7篇 |
1998年 | 14篇 |
1997年 | 13篇 |
1996年 | 19篇 |
1995年 | 8篇 |
1994年 | 18篇 |
1993年 | 12篇 |
1992年 | 3篇 |
1991年 | 2篇 |
1990年 | 4篇 |
1989年 | 13篇 |
1988年 | 5篇 |
1987年 | 10篇 |
1986年 | 14篇 |
1985年 | 12篇 |
1984年 | 7篇 |
1983年 | 7篇 |
1982年 | 7篇 |
1981年 | 9篇 |
1980年 | 7篇 |
1979年 | 2篇 |
1978年 | 1篇 |
1977年 | 6篇 |
1975年 | 4篇 |
1973年 | 1篇 |
排序方式: 共有554条查询结果,搜索用时 15 毫秒
101.
102.
Ocular and orbital lesions: surface coil MR imaging 总被引:1,自引:0,他引:1
Bilaniuk LT; Schenck JF; Zimmerman RA; Hart HR Jr; Foster TH; Edelstein WA; Goldberg HI; Grossman RI 《Radiology》1985,156(3):669-674
Nine lesions, four ocular (three melanomas, one hemangioma) and five orbital (two perioptic meningiomas, one hemangioma, one pseudotumor, one mucocele), were evaluated by magnetic resonance surface coil imaging at 1.5 T. Small ocular lesions with 3.9-4.5-mm-elevation were demonstrated. The use of two different pulse sequences resulted in separation of melanoma from adjacent retinal detachment. Contrast obtained between orbital lesions and the adjacent normal structures was better than that demonstrated with high-resolution computed tomography. 相似文献
103.
Robotic-assisted laparoscopy in gynecological surgery. 总被引:2,自引:0,他引:2
Camran Nezhat Naghmeh S Saberi Babac Shahmohamady Farr Nezhat 《JSLS, Journal of the Society of Laparoendoscopic Surgeons》2006,10(3):317-320
BACKGROUND: Laparoscopic surgery has revolutionized the concept of minimally invasive surgery for the last 3 decades. Robotic-assisted surgery is one of the latest innovations in the field of minimally invasive surgery. Already, many procedures have been performed in urology, cardiac surgery, and general surgery. In this article, we attempt to report our preliminary experience with robotic-assisted laparoscopy in a variety of gynecological surgeries. We sought to evaluate the role of robotic-assisted laparoscopy in gynecological surgeries. METHODS: The study was a case series of 15 patients who underwent various gynecologic surgeries for combined laparoscopic and robotic-assisted laparoscopic surgery. The da Vinci robot was used in each case at a tertiary referral center for laparoscopic gynecologic surgery. An umbilicus, suprapubic, and 2 lateral ports were inserted. These surgeries were performed both using laparoscopic and robotic-assisted laparoscopic techniques. The assembly and disassembly time to switch from laparoscopy to robotic-assisted surgery was measured. Subjective advantages and disadvantages of using robotic-assisted laparoscopy in gynecological surgeries were evaluated. RESULTS: Fifteen patients underwent a variety of gynecologic surgeries, such as myomectomies, treatment of endometriosis, total and supracervical hysterectomy, ovarian cystectomy, sacral colpopexy, and Moskowitz procedure. The assembly time to switch from laparoscopy to robotic-assisted surgery was 18.9 minutes (range, 14 to 27), and the disassembly time was 2.1 minutes (range, 1 to 3). Robotic-assisted laparoscopy acts as a bridge between laparoscopy and laparotomy but has the disadvantage of being costly and bulky. CONCLUSION: Robotic-assisted laparoscopic surgeries have advantages in providing a 3-dimensional visualization of the operative field, decreasing fatigue and tension tremor of the surgeon, and added wrist motion for improved dexterity and greater surgical precision. The disadvantages include enormous cost and added operating time for assembly and disassembly and the bulkiness of the equipment. 相似文献
104.
105.
M Ghanei Dr Assistant Professor Medicine P Adibi Deputy Manager M Movahedi Resident Doctor for Internal Medicine MA Khami Lecturer of Histology RL Ghasemi Vice Chancellor T Azarm Associate Professor Medicine B Zolfaghari Lecturer of Medical Education HR Jamshidi University Chancellor R Sadri Computer Consultant 《Public health》1997,111(3):153-156
Background: Iran like other middle east countries has a large number of major thalassaemics. Due to religious restrictions on abortion, the routine prevention of the birth of thalassaemic children by this means is not possible. The aim of this study is to describe an alternative means to prevent the birth of thalassaemic children.Methods: From January 1993 to January 1996, 100 000 people preparing for marriage were screened for the thalassaemia trait, using CBC and HbA2 level measurement. High risk couples were referred for further consultation regarding the disease and the means of its prevention. The proposed actions of the couples regarding thalassaemia prevention were evaluated immediately after consultation and then re-evaluated three months later. Result: After the project had been running for three years the average of high risk couple initially deciding not to marry was 90% and no new cases of thalassemia were detected in the children of the screened population.Conclusion: Where both members of the couple were trait-positive their preferred choice was not to marry, rather than to marry and use other or no methods of preventing a thalassemia affected child being born to them. Cultural and religious ideas can affect such decisions and in some Islamic countries the establishment and use of a genetic counselling centre can help prevent most of new thalassaemia cases. 相似文献
106.
107.
Yunes Panahi Nahid Khalili Ebrahim Sahebi Soha Namazi Maryam Saberi Karimian Muhammed Majeed Amirhossein Sahebkar 《Inflammopharmacology》2017,25(1):25-31
Background
Oxidative stress has a key role in the pathogenesis of type II diabetes mellitus (T2DM) and its vascular complications. Antioxidant therapy has been suggested as a potential approach to blunt T2DM development and progression. The aim of this study was to assess the effects of supplementation with curcuminoids, which are natural polyphenolics from turmeric, on oxidative indices in diabetic individuals.Methods
In this randomized double-blind placebo-controlled trial, 118 subjects with T2DM were randomized to curcuminoids (1000 mg/day co-administered with piperine 10 mg/day) or matching placebo for a period of 8 weeks. Serum total antioxidant capacity, superoxide dismutase (SOD) activities and malondialdehyde (MDA) concentrations were measured at baseline and after the supplementation period.Results
Curcuminoids supplementation caused a significant elevation in serum total antioxidant capacity (TAC) (p < 0.001) and SOD activities (p < 0.001), while serum MDA levels were significantly reduced compared with the placebo group (p < 0.001). These results remained statistically significant after adjustment for potential confounders (baseline differences in body mass index and fasting serum insulin).Conclusion
The present results support an antioxidant effect of curcuminoids supplementation in patients with T2DM, and call for future studies to assess the impact of these antioxidant effects on the occurrence of diabetic complications and cardiovascular endpoints.108.
109.
HR Chowdhury M Yunus K Zaman A Rahman SM Faruque AG Lescano RB Sack 《Acta paediatrica (Oslo, Norway : 1992)》2001,90(6):605-610
A controlled, randomized, double-blind study in Bangladeshi children (ages 4-36 mo) with acute diarrhoea was undertaken to determine whether bismuth subsalicylate (BSS) would prevent the development of persistent diarrhoea (PD) in young children. The children were randomized to two groups: 226 were given liquid oral BSS, (as Pepto-Bismol), 100 mg/kg/d for 5 d; 225 were given placebo of identical appearance. On admission to the study, the two groups were comparable both clinically and microbiologically. Rotavirus was found in 56% of all the children, and enterotoxigenic E. coli in 31% of a subsample studied. Children treated with BSS had less severe and less prolonged illness than those treated with placebo (p = 0.057). There was, however, no difference in the development of PD between the two groups (8% and 11%). Unexpectedly, patients treated with BSS gained significantly more weight (2.3%) than those treated with placebo (0.5%; p < 0.001) during the course of the study. No toxicity of BSS was detected. Conclusion: Treatment with BSS had a modest therapeutic effect on acute diarrhoea, as has been previously demonstrated, but with no suggestion of a therapeutic effect on the prevention of persistent diarrhoea in this group of patients. 相似文献
110.
To evaluate the surgical outcome in terms of functional and subjective recovery, patients who needed discectomies at L1–L2,
L2–L3 and L3–L4 levels were compared with an age and sex-matched group of patients who required L4–L5 and L5–S1 discectomies.
We prospectively enrolled 50 consecutive patients, referred to our center, who had L1–L2, L2–L3 and L3–L4 herniations and
required surgical intervention. Likewise, a comparative group of 50 consecutive patients with herniations at L4–L5 and L5–S1
were selected. All 100 patients were treated and followed for a 1 year period. Physical examination findings as well as Oswestry
Disability Questionnaire before surgery were recorded. After 1 year, patients were requested to fill the same questionnaire.
Significant decline in the Oswestry Disability Index (ODI) scores was considered to be a measure of functional improvement
and recovery. The mean age of patients with upper lumbar disc herniation (L1–L2, L2–L3, L3–L4) was 45.7 years and patients
with lower lumbar disc herniation (L4–L5, L5–S1) had a mean age of 41.2 years. There was no statistically significant difference
in age between the two groups. The preoperative Oswestry Disability (ODI) Index score had a statistically significant impact
on ODI score improvement after surgery in both lower and upper lumbar disc groups. All 100 patients with either lower or upper
lumbar disc herniation had statistically significant ODI change after surgical intervention (P < 0.0001 for both groups). However, patients with upper disc herniations and moderate preoperative disability (ODI of 21–40%)
did not show significant improvement, while patients with ODI greater than 40% had significant reduction (P = 0.018). Surprisingly, as many as 25% of the former had even an increase in ODI scores after surgery. Gender was also a
conspicuous factor in determining the surgical outcome of patients with upper lumbar disc herniation, and male patients had
more reduction in ODI score than female patients (P = 0.007). Since the functional recovery in patients with herniated lumbar disc, especially upper lumbar herniation, is influenced
by preoperative ODI scores, the use of ODI or any other standard pain assessment tool is a sensible consideration as an inherent
investigative method to preclude unfavorable surgical outcome. 相似文献