绵阳市农村狂犬病防治知识调查

目的了解绵阳市农村人群对狂犬病防治知识的知晓情况,为开展有效健康教育提供依据。方法采用自行设计调查问卷分层抽样,以绵阳市9个县市区农村居民和学生为调查对象,进行入屋调查。结果共有效调查894人,学生331人,农民563人。调查对象狂犬病基本知识知晓率为86.99%;狂犬病伤口处理和疫苗注射相关知识知晓率为55.13%;养犬相关法规知识知晓率为71.67%。结论绵阳市农村人群狂犬病的知晓率偏低,是健康教育的重点人群。     

浅谈象思维在认识中药功效方面的应用

象思维是中医药学最主要的思维方法之一,尤其对中药功效方面的发展起着重要作用。象思维与中国传统文化思想有着千丝万缕的联系,它的发展与中国哲学思想密不可分;而中药学是研究中药的基本理论和临床应用并且在中华文化的滋养下发展壮大的学科,故象思维与中药学存在相互影响与作用,象思维对中药功效方面的影响深远。     

热毒宁治疗急性肠炎发热疗效观察

目的：观察热毒宁治疗腹泻发热的疗效。方法我院急诊2013年1月-2013年12月就诊的肠炎发热患者82例，将患者随机分为观察组（41例）和对照组（41例）。对照组给予对症处理，观察组在对照组的基础上，静脉滴注热毒宁注射液20 mL，1次/d。两组疗程均为3d。结果观察组治愈36例，好转4例，无效1例；对照组治愈23例，好转9例，无效9例。两组疗效比较差异有统计学意义（P＜0.05）。结论热毒宁注射液治疗急性肠炎发热疗效显著。     

TBX1����ͻ��������Բ׶�����ɻ��ι�ϵMeta����

??Abstracts?? Objective To evaluate the association between TBX1 gene mutation and conotruncal defects ??CTDs?? using Meta-analysis. Methods Studies on the relationship between TBX1 gene mutation and CTDs were searched from the databases of Wanfang?? VIP?? CNKI?? PubMed?? Elsevier Science Direct and Cochrane Library from their establishment date to September of 2013. According to the standards of inclusion and exclusion?? articles were evaluated. Poor quality studies were excluded. Relevant data were extracted from eligible studies to conduct meta-analysis. R2.15.3 software was applied for statistical analysis. Results Eight eligible studies involving 851 patients were analyzed in the study?? including 6 English literatures and 2 Chinese literatures. Three studies found 15 gene mutations?? and 5 studies found 26 gene polymorphisms. The results of Meta-analysis showed that the pooled TBX1 gene mutation rate was 2.13%??95??CI??0.76%—5.87%??. Conclusion The TBX1 gene mutation rate is low in CTDs patients. TBX1 gene mutation may not be the main genetic factor for CTDs.     

Zephyr5826起搏器心房自动阈值管理的临床观察

目的动态观察Zephyr5826起搏器心房自动阈值管理(ACM)功能的开启情况、准确性及安全性。方法选取置入Zephyr5826起搏器患者68例,于置入术后第1,7天及1,2,3,6个月时随访程控,观察ACM功能的开启情况,手工测试心房起搏阈值并与ACM功能测定的值进行比较。结果 68例均完成随访。随访期内35例(51.50%)成功开启ACM功能,其中术后第1,7天及1,2,3个月时开启例数分别为14例(20.6%)、21例(30.9%)、26例(38.2%)、28例(41.2%)和32例(47.1%)。手工测试与ACM测试的心房阈值无差异。33例因起搏器自动测定心房刺激除极波(ER)过小不推荐开启ACM功能。随访期间心电图及动态心电图(Holter)均未见心房失夺获及感知不良。与普通电压和高电压起搏相比,自动阈值管理功能在心房输出方面分别节省50%,88%的能量消耗。结论 Zephyr5826起搏器ACM功能可以安全有效的应用低能量起搏心脏。部分患者术后因起搏器测定心房ER过小未能开启ACM功能,但在随访过程中ACM的开启比例逐渐升高。     

GE Lightspeed VCT球管灯丝开路故障和球管更换

本文分析了GE Lightspeed VCT球管灯丝开路的故障现象,并介绍了故障排除的过程。     

�����ȳ��ͼ����ȳ���С��̥������������Ƚ�

??Objective??To find the difference in growth and development of children between full-term symmetric growth restriction??FSGR?? and full-term asymmetric growth restriction??FAGR?? through a general investigation of children born small for gestational age in Shanghai. Methods??This general investigation covered all children under 6 years old in Shanghai. Data on growth were retrospectively obtained from medical records. The P10 of birth head circumference/birthweight of the same gestational age and gender was used to distinguish FSGR and FAGR. Results??The sample contained 10 188 full-term SGA children among whom 8049 were FAGR and 2139 were FSGR. Up to 3 years old??both FSGR and FAGR failed to catch up in weight??height??head circumference and chest circumference. Growth restriction in FAGR was more serious. Significant difference could be seen in weight??t??-3.412??P??0.001?? and chest circumference??t??-2.526??P??0.012?? between FSGR and FAGR at 3 years old. Regarding growth speed??the growth rate of weight ??t??6.272??P??0.001????height ??t??9.143??P??0.001????head circumference ??t??6.063??P??0.001?? and chest circumference ??t??6.617??P??0.001?? were higher in FAGR 6 months after birth??while there was no difference after that. The BMI of FAGR was significantly lower than FSGR before 2 years old. The proportion of children in danger of being overweight was significantly higher in FSGR ??P??0.001??. Conclusion??Both FSGR and FAGR experience catch-up growth after birth??but not enough to catch up with normal children at 3 years old??especially in head circumference. In spite of severer growth restriction??the cath-up growth model of FAGR is superior to FSGR. The proportion of children in danger of being overweight is significantly higher in FSGR.     

CDIC 系统种植治疗的长期临床效果观察

目的 通过对9084 颗种植体的临床观察分析,评价CDIC 系统种植体植入效果.方法 收集1987 年6 月至2011 年6 月接受种植治疗的患者4215 例,随访观察3 ～18 年,观察分析患者年龄、性别、种植部位及方法,牙龈和牙周状况,X 线平片表现.结果 4108 例患者中男2319 例,女1789 例,年龄22 ～70 岁,平均42.5 岁.上下后牙区植入5021 颗种植体,上前牙区植入3374 颗种植体,下前牙区植入689 颗种植体.上颌窦内提升(经牙槽嵴顶冲顶上颌窦提升)同期种植796 例,组织引导再生植骨同期种植1863 例,早期失败15 颗,均为修复后咀嚼食物不慎致种植体松动,5 年无松动脱落,8 年脱落74 颗,10 年脱落72 颗.结论 CDIC 系统临床应用操作简便,植入效果良好,10 年存留率96.6%.     

曲古霉素A对人膀胱癌细胞EJ增殖的影响及其作用机制

目的 探讨曲古霉素A(TSA)对人膀胱癌细胞EJ增殖及WNT抑制因子-1(WIF-1)mRNA表达的影响,并分析其可能的作用机制.方法 采用四甲基偶氮唑蓝(MTT)比色法检测不同浓度的TSA对人膀胱癌细胞EJ增殖的影响;采用流式细胞术检测经TSA处理后人膀胱癌细胞EJ的细胞周期分布情况;采用实时逆转录聚合酶链反应(RT-PCR)检测用药前后人膀胱癌细胞EJ中WIF-1 mRNA的表达情况;采用染色质免疫沉淀技术分析用药前后WIF-1基因启动子区组蛋白H3第9位赖氨酸(H3-K9)的乙酰化状态.结果 MTT比色法检测结果显示,处理72 h后,0.1、0.2、0.4、0.8和1.6μmol/L人膀胱癌细胞EJ的增殖抑制率均高于空白对照组(P﹤0.05).流式细胞仪检测结果显示,人膀胱癌细胞EJ经0.2、0.4和0.8μmol/L浓度的TSA处理72 h后,G0/G1期、G2/M期细胞的数量随着TSA浓度的升高而逐渐增加,S期细胞的数量随着TSA浓度的升高而逐渐减少.RT-PCR检测结果显示,与空白对照组相比,不同浓度(0.2、0.4和0.8μmol/L)的TSA处理24、48、72 h后,人膀胱癌细胞EJ中WIF-1 mRNA的相对表达量均升高(P﹤0.05).琼脂糖凝胶电泳结果显示,电泳条带符合预期的片段长度,经TSA处理后,人膀胱癌细胞EJ中扩增出目的片段,且随着TSA浓度的增加,目的片段的产物增多.结论 TSA对人膀胱癌细胞EJ的增殖具有抑制作用,其作用机制可能涉及细胞周期阻滞、WIF-1基因启动子区组蛋白H3-K9乙酰化水平升高及该基因的表达水平升高.     

临床教师职业倦怠的相关影响因素分析

目的探讨职业倦怠的主要影响因素及与教学质量的相关性。方法对97名参与临床教学的医护人员进行调查,分析职业倦怠现状、影响因素,及职业倦怠与教学质量的相关性。结果97名临床教师中,存在轻度倦怠41例(42.27%),中度倦怠23例(23.71%),重度倦怠9例(9.28%),合计共有73名临床教师存在职业倦怠(75.26%)。女性情感耗竭维度得分高于男性(P<0.05)。不同职称者情感耗竭、人格解体和成就感降低3个维度得分均差异有统计学意义(P<0.05)。多因素Logistic回归分析结果显示:婚姻状况和职称为职业倦怠的风险因素(P<0.05)。轻度倦怠与重度倦怠者社会支持利用度得分差异有统计学意义(P<0.01)。Spearman等级相关分析结果显示:职业倦怠程度与教学质量评议分数无相关性(P>0.05),职称与教学质量评议分数有正相关关系(P<0.05)。结论临床教师职业倦怠强度与职称、婚姻状况有关。临床教师职称与教学质量正相关。