全文获取类型
收费全文 | 764篇 |
免费 | 17篇 |
专业分类
耳鼻咽喉 | 5篇 |
儿科学 | 49篇 |
妇产科学 | 18篇 |
基础医学 | 85篇 |
口腔科学 | 10篇 |
临床医学 | 94篇 |
内科学 | 171篇 |
皮肤病学 | 23篇 |
神经病学 | 42篇 |
特种医学 | 1篇 |
外科学 | 138篇 |
综合类 | 9篇 |
预防医学 | 18篇 |
眼科学 | 4篇 |
药学 | 52篇 |
中国医学 | 3篇 |
肿瘤学 | 59篇 |
出版年
2023年 | 4篇 |
2022年 | 21篇 |
2021年 | 18篇 |
2019年 | 5篇 |
2017年 | 6篇 |
2016年 | 4篇 |
2015年 | 18篇 |
2014年 | 14篇 |
2013年 | 12篇 |
2012年 | 16篇 |
2011年 | 9篇 |
2010年 | 15篇 |
2009年 | 22篇 |
2008年 | 13篇 |
2007年 | 8篇 |
2006年 | 39篇 |
2005年 | 24篇 |
2004年 | 20篇 |
2003年 | 17篇 |
2002年 | 12篇 |
2001年 | 10篇 |
2000年 | 5篇 |
1999年 | 11篇 |
1998年 | 36篇 |
1997年 | 39篇 |
1996年 | 29篇 |
1995年 | 39篇 |
1994年 | 29篇 |
1993年 | 21篇 |
1992年 | 16篇 |
1991年 | 14篇 |
1990年 | 3篇 |
1989年 | 11篇 |
1988年 | 7篇 |
1987年 | 3篇 |
1986年 | 9篇 |
1985年 | 8篇 |
1984年 | 9篇 |
1981年 | 5篇 |
1980年 | 3篇 |
1979年 | 3篇 |
1977年 | 4篇 |
1976年 | 3篇 |
1959年 | 7篇 |
1958年 | 21篇 |
1957年 | 30篇 |
1956年 | 38篇 |
1955年 | 30篇 |
1954年 | 22篇 |
1948年 | 4篇 |
排序方式: 共有781条查询结果,搜索用时 0 毫秒
691.
MICHIKO KOBAYASHI YASUKO NAYA ATSUKO SUZUKI YOKO KATO YOSHIKO HIRATA DAVID GOUGH 《Pediatrics international》1995,37(2):272-278
Cases of child abuse identified by a hot-line telephone service and by a survey of health and welfare agencies are reported. Many consultations to the telephone hot-line were from mothers concerned about maltreating their own children. In such cases, the extent of abuse was often mild to moderate, and many of those mothers were troubled about child care in the relatively segregated context of the nuclear family. In only a few cases did the callers indicate that the children's life was in danger. In the administrative survey, however, deaths occurred in 5% of the cases, and the abused children frequently had physical and psychological symptoms. There were also more frequent and more serious family problems in the administrative survey compared to the telephone consultation cases. The findings of these surveys suggest that many children and parents are suffering from child abuse in Japan, that many cases are currently not being identified by health and welfare agencies, and that a wide range of measures, from protection of severely abused children to prevention of abuse, are necessary. 相似文献
692.
TOYA OHASHI TAKAHIRO TAHARA KOUJI FUJISAWA YASUTAKA HOSHI FUMIYUKI ITO NAOKI SUZUKI YOSHIKATSU ETO KIHEI MAEKAWA 《Pediatrics international》1995,37(6):697-700
Bone marrow transplantation (BMT) was performed in a 3 year old patient with Hurler syndrome. The post-BMT course was complicated by interstitial pneumonitis and severe hypertension, which were life threatening. The patient responded well to therapy and recovered. BMT in this patient resulted in significant clinical improvement in the signs and symptoms of Hurler syndrome. Biochemical improvement, including elevated α-l -iduronidase activity in white blood cells and decreased urinary glycosaminoglycan excretion was significant. However, skeletal and neurological impairment were not improved. We conclude that BMT for Hurler syndrome should be performed at an earlier stage, before severe neuronal damage has occurred. Moreover, BMT is a high risk procedure and there will always be a possibility that life threatening complications will occur, as in our case. 相似文献
693.
Hiroshi WATANABE Ryoma SUZUKI Tomoyuki ASANO Kiori SHIO Haruyo IWADATE Hiroko KOBAYASHI Toshimitsu MATSUOKA Ken AIKAWA Hiromasa OHIRA 《International journal of rheumatic diseases》2010,13(2):180-183
Rheumatoid arthritis (RA) is a systemic autoimmune disease that is characterized by chronic synovial inflammation. Patients with RA have increased risk of infection; this is related to RA itself or the adverse effects of medication. In this report, we describe a case of emphysematous pyelonephritis in a patient with RA associated with AA amyloidosis and steroid‐induced diabetes mellitus who was taking corticosteroid and low‐dose methotrexate. 相似文献
694.
SUSUMU TOMIOKA HIROOMI NAKATSU NORIYUKI SUZUKI SHINO MURAKAMI OSAMU MATSUZAKI JUN SHIMAZAKI 《International journal of urology》2006,13(5):555-559
AIM: Although the histopathological findings obtained from biopsy specimens are important for choosing the appropriate management of prostate cancer, there have been some discrepancies in Gleason grade and consequently, score between biopsy and surgical specimens. A comparison of findings between these two kinds of specimens was performed. METHODS: Radical prostatectomy was performed at Asahi General Hospital on 223 cases of T1b-T3 without previous cancer treatment, and the Gleason grade and score of the biopsy and surgical specimens were compared. RESULTS: A 37% coincidence in Gleason score was obtained between biopsy and surgical specimens; coincidence including one digit difference in score was approximately 70%. Upgrading was more than downgrading. Disagreement in secondary grade was greater than that in primary grade. Disagreement in Gleason score was roughly similar among different score items and was not influenced by level of prostate-specific antigen, however, the small volume of the cancer tissues more affected the discrepancy in score. CONCLUSION: The use of biopsy findings is required to be taken into account regarding the discrepancy. 相似文献
695.
KENJI IKEDA MASAHIRO KOBAYASHI SATOSHI SAITOH TAKASHI SOMEYA TETSUYA HOSAKA HITOMI SEZAKI YOSHIYUKI SUZUKI FUMITAKA SUZUKI NORIO AKUTA YASUJI ARASE HIROMITSU KUMADA 《Journal of gastroenterology and hepatology》2006,21(1):183-190
Background: To elucidate the origin of the neovascular structure found in well‐differentiated hepatocellular carcinoma (HCC), an immunohistochemical study was performed on sequential thin section specimens. Method: Eleven surgically resected specimens of well‐differentiated HCC were analyzed for neovascular structure using monoclonal alpha‐smooth muscle actin (α‐SMA) antibody. Each paraffin specimen was serially sliced to a thickness of 3 µm for immunohistochemistry. When a ring‐shaped structure was found unrelated to portal triads on α‐SMA staining, it was regarded as abnormal neovascularity (non‐triadal vessel or unaccompanied vessel). Results: All of the 11 liver cancers had thin‐walled, round‐ or oval‐shaped non‐triadal vessels in their well‐differentiated parts. Immunohistochemistry of serial thin sections of HCC showed that these non‐triadal vessels were connected to portal veins in portal triads in well‐differentiated cancer in a total of nine patients (81.8%). This type of neovascular structure found in a well‐differentiated cancer seemed to be a surviving portal vein among diminishing and disappearing arteries and bile ducts. All 11 tumors showed isovascular staining on ordinary digital subtraction angiography, and four of the tumors showed negative enhancement on intra‐arterial carbon dioxide‐enhanced ultrasonography or computerized tomographic (CT) hepatic arteriography, suggesting a relative arterial blood scarcity in the tumor nodules. Conclusion: At an early stage of HCC, non‐triadal vessels originate from ordinary portal veins in intratumoral portal triads. This fact sufficiently explains the reason why a well‐differentiated liver cancer can sometimes show arterial blood paucity on CT arteriography or enhanced ultrasonography. 相似文献
696.
Pham Dang BANG Koichi SUZUKI Le Thi PHUONG Tran Man CHU Norihisa ISHII Tran Hau KHANG 《The Journal of dermatology》2009,36(5):269-276
Because Mycobacterium leprae cannot be cultivated in vitro , laboratory diagnosis of leprosy is generally made by microscopic and histopathological examination. The objective of the present study was to evaluate the sensitivity and utility of polymerase chain reaction (PCR) to detect M. leprae in comparison with other conventional methods for diagnosis such as split skin smears, histopathology and serodiagnosis. PCR amplification of the M. leprae -specific 16S ribosomal RNA was compared to other methods. Samples included 37 multibacillary (MB) patients with a positive bacteriological index (BI), 32 newly diagnosed paucibacillary (PB) patients whose BI were negative and 30 plaque psoriasis patients not residing in leprosy endemic areas as controls. The sensitivity of PCR was 30 fg of M. leprae DNA, which is equivalent to the DNA from 8.3 bacilli. The detection rate in MB and PB were 100% and 50%, respectively; the specificity was 100%. Semiquantitative evaluation of PCR correlated well with BI, but not with the morphological index (MI) nor with the serum antibody against phenolic glycolipid-1 (PGL-1). PCR detection of M. leprae targeting 16S ribosomal RNA was specific and more sensitive than conventional methods, and can contribute to early and accurate diagnosis of leprosy. 相似文献
697.
Akiko YAGAMI Yasuko INABA Yuki KUNO Kayoko SUZUKI Akira TANAKA Sigrid SJOLANDER Hirohisa SAITO Kayoko MATSUNAGA 《The Journal of dermatology》2009,36(1):50-55
Oral allergy syndrome to soy milk is classified as a phenotype of pollen-food allergy syndrome (PFAS). As causative antigens, Gly m 4 (Bet v 1 homolog, 17 kD) and oleosin (23 kD), have been reported. In this study, we report two cases of PFAS to soy milk. Both cases showed positive reactions to soy milk in skin prick tests (SPT) and to Gly m 4 in specific serum immunoglobulin (Ig)E antibody. When we measured specific serum IgE antibody of soy-related proteins using a new laboratory testing method, microarray analysis, both cases showed a positive reaction for Bet v 1. One case was weakly positive for a soybean protein, β-conglycinin. Other results for reactivity to soy, peanut, cross-reactive carbohydrate determinants and profilin were negative. Based on these results, we diagnosed the two cases as PFAS to Gly m 4. We also performed protein microarray analysis and found it useful as a screening test for immediate allergy, such as PFAS. 相似文献
698.
699.
700.