Effect of phospholipid hepatoprotectors on the course of experimental Reye's syndrome

Hepatoprotectors containing phospholipids exert a therapeutic effect in experimental Reye's syndrome in rats induced by 40pentenoic acid. Eplir more effectively than essentiale decreased necrosis of the liver, reduced serum enzymes and bilirubin, alleviated hypoglycemia, suppressed MDA production, and improved ketogenesis and detoxication of ammonium and phenols. Translated fromByulleten' Eksperimental' noi Biologii i Meditsiny, Vol. 129, No. 3, pp. 337–339, March, 2000     

Standardization of the Food Composition Database Used in the Latin American Nutrition and Health Study (ELANS)

Between-country comparisons of estimated dietary intake are particularly prone to error when different food composition tables are used. The objective of this study was to describe our procedures and rationale for the selection and adaptation of available food composition to a single database to enable cross-country nutritional intake comparisons. Latin American Study of Nutrition and Health (ELANS) is a multicenter cross-sectional study of representative samples from eight Latin American countries. A standard study protocol was designed to investigate dietary intake of 9000 participants enrolled. Two 24-h recalls using the Multiple Pass Method were applied among the individuals of all countries. Data from 24-h dietary recalls were entered into the Nutrition Data System for Research (NDS-R) program after a harmonization process between countries to include local foods and appropriately adapt the NDS-R database. A food matching standardized procedure involving nutritional equivalency of local food reported by the study participants with foods available in the NDS-R database was strictly conducted by each country. Standardization of food and nutrient assessments has the potential to minimize systematic and random errors in nutrient intake estimations in the ELANS project. This study is expected to result in a unique dataset for Latin America, enabling cross-country comparisons of energy, macro- and micro-nutrient intake within this region.     

Troponin Testing in Patients Without Chest Pain or Electrocardiographic Ischemic Changes

Background

Although often recommended by experts, it is unclear if elevated troponin measurements have clinical utility in patients without chest pain or ischemic electrocardiographic changes.

Antihypoxic, cardioprotective, and antifibrillation effects of a combined adaptogenic plant preparation

The course of treatment with combined adaptogenic plant preparation Tonizid improved mouse survival under conditions of hypobaric hypoxia and reduced the necrotic zone/risk zone ratio during ischemia and reperfusion in rats under conditions of artificial ventilation. The test preparation decreased the size of the necrotic zone, but had no effect on the size of the risk zone. Tonizid prevented ventricular fibrillation during coronary occlusion and exhibited antihypoxic, cardioprotective, and antifibrillation properties. __________ Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 142, No. 8, pp. 177–180, August, 2006     

Remote results of surgical treatment of the patients with multilevel atherosclerotic damage of the main arteries of the lower extremity

The results of treatment of 131 patients, suffering multilevel atherosclerotic affection of abdominal aorta and the main arteries of the lower extremity, are adduced. Algorhythm of arterial reconstruction performance depending on the spread of the aorto-iliac and femoro-politeal segments affection, was elaborated. There were applied two methods of treatment: reconstruction of aorto-iliac segment only and simultaneous reconstruction of arteries on two levels. The differentiated approach to performance of arterial reconstruction application have permitted to achieve positive result in 80% of patients in terms of 5-year follow-up. The lower extremity was secured in 83% of them, mortality had constituted 20%.