全文获取类型
收费全文 | 1616篇 |
免费 | 98篇 |
国内免费 | 33篇 |
专业分类
耳鼻咽喉 | 16篇 |
儿科学 | 60篇 |
妇产科学 | 8篇 |
基础医学 | 200篇 |
口腔科学 | 51篇 |
临床医学 | 111篇 |
内科学 | 300篇 |
皮肤病学 | 34篇 |
神经病学 | 58篇 |
特种医学 | 234篇 |
外科学 | 177篇 |
综合类 | 37篇 |
预防医学 | 77篇 |
眼科学 | 8篇 |
药学 | 67篇 |
肿瘤学 | 309篇 |
出版年
2022年 | 10篇 |
2021年 | 14篇 |
2020年 | 8篇 |
2019年 | 18篇 |
2018年 | 29篇 |
2017年 | 18篇 |
2016年 | 17篇 |
2015年 | 32篇 |
2014年 | 43篇 |
2013年 | 41篇 |
2012年 | 55篇 |
2011年 | 72篇 |
2010年 | 53篇 |
2009年 | 46篇 |
2008年 | 66篇 |
2007年 | 60篇 |
2006年 | 69篇 |
2005年 | 57篇 |
2004年 | 49篇 |
2003年 | 56篇 |
2002年 | 38篇 |
2001年 | 48篇 |
2000年 | 42篇 |
1999年 | 41篇 |
1998年 | 46篇 |
1997年 | 47篇 |
1996年 | 47篇 |
1995年 | 41篇 |
1994年 | 29篇 |
1993年 | 39篇 |
1992年 | 31篇 |
1991年 | 31篇 |
1990年 | 21篇 |
1989年 | 34篇 |
1988年 | 38篇 |
1987年 | 51篇 |
1986年 | 27篇 |
1985年 | 22篇 |
1984年 | 11篇 |
1983年 | 16篇 |
1982年 | 20篇 |
1981年 | 25篇 |
1980年 | 18篇 |
1979年 | 12篇 |
1978年 | 9篇 |
1977年 | 15篇 |
1976年 | 26篇 |
1975年 | 14篇 |
1971年 | 8篇 |
1968年 | 8篇 |
排序方式: 共有1747条查询结果,搜索用时 15 毫秒
41.
Eduardo Álvarez-Sarrado Fernando Mingol Navarro Raquel J. Rosellón Neus Ballester Pla Francisco Javier Vaqué Urbaneja Carmen Muniesa Gallardo María López Rubio Eduardo García-Granero Ximénez 《American journal of surgery》2019,217(1):114-120
Background
Patients undergoing esophagectomy for cancer usually deal with malnourishment which increases postoperative morbimortality. The objective of this paper is to analyze the nutritional benefits of feeding jejunostomy (FJ) for early postoperative enteral nutrition (EN) and directly-related complications.Material and methods
Retrospective study of 100 patients undergoing esophagectomy for cancer between 2008 and 2016.Results
FJ was placed in 47 patients. 82.98% reached EN requirements in FJ group, with a median EN re-start of 1.9 days and median days to objective requirements of 5 days.51.06% developed directly-related FJ complication, 91.66% of them mild ones (gastrointestinal or catheter-related). 2 patients (4.25%) required re-intervention.No significant differences were shown in total protein and albumin seric levels during first postoperative week and in anastomotic leak rate between both groups (p?>?0.05).Conclusions
Feeding jejunostomies are associated with a great number of complications although most are not life-threatening. Since its nutritional benefit is not proven FJ cannot routinely recommended after esophagectomy. However, the optimal pathway for EN reintroduction, including direct oral intake, is still a matter of debate. 相似文献42.
43.
44.
45.
Mar Hernández-Guillamon Laura Ortega Cristina Merino-Zamorano Mireia Campos-Martorell Anna Rosell Joan Montaner 《Journal of neural transmission (Vienna, Austria : 1996)》2014,121(2):113-117
Most of neuroprotective strategies in stroke have failed to move from bench to bedside. One explanation might be the use of excessive uniform and smooth experimental models. Therefore, we have employed a more stringent in vitro model based on cultured brain slices from adult mice submitted to OGD. Using this acute model, we have confirmed that mild hypothermia protects against OGD-induced cell death when cooling the tissue during and after OGD, but not when hypothermia is induced only during reoxygenation. 相似文献
46.
47.
48.
Reza Saeidi Pour DR MED DENT Otto Zuhr DR MED DENT Markus Hürzeler PROF DR MED DENT Otto Prandtner MDT Caroline Freitas Rafael Daniel Edelhoff PROF DR MED DENT Anja Liebermann DR MED DENT 《Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.]》2017,29(2):93-101
49.
García-Civera R Ruiz-Granell R Morell-Cabedo S Sanjuan-Mañez R Ferrero A Martínez-Brotons A Roselló A Botella S Llacer A 《Journal of cardiovascular electrophysiology》2005,16(9):938-942
BACKGROUND: The diagnostic significance of a tilt table test (TTT) in patients with a suspected arrhythmic etiology for syncope and negative electrophysiologic study (EPS) has not been previously assessed comparing the TTT results with the findings of prolonged monitoring using an implantable loop recorder (ILR). We sought to assess the diagnostic yielding of TTT in patients with suspected arrhythmic syncope and negative EPS. METHODS AND RESULTS: In 81 patients with suspected arrhythmic etiology for syncope and negative EPS, TTT was performed and an ILR implanted regardless the results of TTT. TTT was positive in 38 patients. During follow-up, syncope or presyncope recurred in 32 patients (39.5%). No differences were found in recurrence rates in patients with positive and negative TTT (31.5% vs 46.5%, P = ns). According to rhythm registered during ILR activation, mechanisms of syncopal events were classified as: arrhythmic (atrioventricular [AV] block and ventricular tachycardia; n = 18), neurally mediated (sinus bradycardia and sinus pause; n = 9), and indeterminate (normal sinus rhythm; n = 5). There was no statistical association between the results of TTT and the mechanism of syncope. CONCLUSIONS: In patients with a suspected arrhythmic etiology for syncope and a negative EPS, TTT is of little value to predict the mechanism of syncope and the ILR implantation seems to be a useful and safe diagnostic strategy. 相似文献
50.
BACKGROUND & AIMS: Shwachman syndrome is an inherited condition with multisystemic abnormalities, including exocrine pancreatic dysfunction. The aim of this study was to evaluate the occurrence and progression of features in a large cohort of patients. METHODS: Clinical records of 25 patients with Shwachman syndrome were reviewed. RESULTS: Mean birth weight (2.92 +/- 0.51 kg) was at the 25th percentile. However, by 6 months of age, mean heights and weights were less than the 5th percentile. After 6 months of age, growth velocity was normal. Severe fat maldigestion due to pancreatic insufficiency was present in early life (fecal fat, 26% +/- 17% of fat intake; age, < 2 years). Serial assessment of exocrine pancreatic function showed persistent deficits of enzyme secretion, but 45% of patients showed moderate age-related improvements leading to pancreatic sufficiency. Neutropenia was the most common hematologic abnormality (88%), but leukopenia, thrombocytopenia, and anemia were also frequently encountered. Patients with hypoplasia of all three bone marrow cellular lines (n = 11) had the worst prognosis; 5 patients died, 2 of sepsis and 3 of acute myelogenous leukemia. Other findings included hepatomegaly and/or abnormal liver function test results and skeletal abnormalities. CONCLUSIONS: A wide and varied spectrum of phenotypic abnormalities among patients with Shwachman syndrome is described. Pancreatic acinar dysfunction is an invariable abnormality. Patients with severe bone marrow involvement may have a guarded prognosis. (Gastroenterology 1996 Dec;111(6):1593-602) 相似文献