改良钳夹型脊髓损伤大鼠模型的建立及神经功能评价简

目的：建立一种稳定可靠、操作简单的不完全性脊髓损伤动物模型,并对其神经功能进行初步评价。方法将50只SD大鼠随机分为模型组、假手术组。采用改良钳夹法建立大鼠脊髓损伤模型,观察不同时间点大鼠行为学运动功能（BBB）评分、脊髓组织形态变化及损伤段脊髓的细胞凋亡因子半胱氨酸蛋白酶3（Caspase-3）阳性细胞表达的情况。结果模型组大鼠各时间点BBB评分均明显低于假手术组（P＜0.05）,假手术组各时间点大鼠脊髓组织中Caspase-3阳性细胞表达明显低于模型组（P＜0.05）。结论成功制备了稳定可靠、操作简单的不完全性脊髓损伤动物模型。     

Popliteal artery entrapment syndrome in a young girl: case report of a rare finding

The popliteal artery (PA) entrapment syndrome, a rare cause of arterial thrombosis, is most often encountered in young male athletes. Here, we report a very unusual case of PA entrapment syndrome in a 14-year-old girl who presented with a 1-month history of calf claudication to our observation facility. Diagnostic work-up revealed obesity, sedentary lifestyle, and an aberrant accessory slip of the medial head of gastrocnemius around the PA. Arterial echo color Doppler ultrasonography and computed tomographic angiography studies were performed. Surgical treatment involved revascularization with resection of the medial head of gastrocnemius, the cause of the arterial entrapment, and enlargement angioplasty using an autologous saphenous vein patch, in combination with antiplatelet therapy, resulting in restitution ad integrum of the affected limb and, finally, an improved quality of life of the patient. This case underscores the importance of clinical suspicion, diagnosis, and treatment of lower-limb claudication in very young patients presenting with unusual symptoms. If missed, the condition may evolve dramatically. Prompt diagnosis and surgical treatment are key to complete recovery and the prevention of irreversible complications that may result in limb loss.     

Incidence of Cancer Following Bariatric Surgery: Systematic Review and Meta-analysis

Obesity is linked to the development of cancer. Previous studies have suggested that there is a relationship between bariatric surgery and reduced cancer risk. Data sources were from Medline, Embase, and Cochrane Library. From 951 references, 13 studies met the inclusion criteria (54,257 participants). In controlled studies, bariatric surgery was associated with a reduction in the risk of cancer. The cancer incidence density rate was 1.06 cases per 1000 person-years within the surgery groups. In the meta-regression, we found an inverse relationship between the presurgical body mass index and cancer incidence after surgery (beta coefficient ?0.2, P?相似文献   

带锁髓内钉治疗股骨干骨折并发症原因分析及防治

目的提高带锁髓内钉的治疗效果,减少术中术后的并发症。方法自1998年10月～2001年10月用带锁髓内钉治疗的160例股骨干骨折,随访6～18个月。结果股骨颈骨折2例,主钉折断2例,锁钉折断2例,锁钉松动退出3例,术后感染4例,骨折延迟愈合6例。结论带锁髓内钉是治疗股骨干骨折较好的治疗方法,分析产生合并症的原因后采取各种防治措施可明显降低并发症的发生率。     

Nursing care for patients receiving injection of sclerosing foam for varix of lower limb

对52例下肢静脉曲张患者采用聚桂醇泡沫硬化剂注射治疗,结果所有病例成功注射聚桂醇泡沫硬化剂,未出现深静脉血栓形成、肺栓塞等严重并发症.注射后2～3 d出院.1个月后复查治疗效果显著47例,行二次治疗4例,1例复发.提出注射前做好物品准备、皮肤护理及心理护理等,注射时严格遵守无菌操作原则、注射剂量准确,注射后做好肢体、注射部位护理,并发症的预防及处理,是保证治疗顺利进行及治疗效果的措施之一.     

维持性血液透析患者矿物质代谢研究

目的 探讨新乡地区维持性血液透析（MHD）患者矿物质代谢现况及相关影响因素,以提高本地区MHD患者生存质量.方法 收集2012年1月至2013年8月新乡地区4家综合性医院466例MHD3个月以上患者的临床资料.检测血清钙离子、磷、全段甲状旁腺激素（iPTH）及碱性磷酸酶（ALP）水平.分析MHD患者矿物质代谢现况及其与年龄、透析龄、营养不良、透析充分性的关系.结果 466例患者血钙平均值为（1.95±0.34） mmol/L,血磷平均值为（2.54± 1.38）mmol/L,iPTH平均值为（409±346）ng/L;钙、磷、iPTH达标率分别为34.3％（160/466）、20.4％（95/466）和25.5％ （119/466）.年龄≥60岁组（n=159）患者的血磷[（2.27±0.95）mmol/L比（2.68± 1.54） mmol/L]、iPTH[（344±235） ng/L比（437±383）ng/L]、ALP值[（49.0±36.4）mmol/L比（77.1±78.5） mmol/L]均低于年龄＜60岁组（n=307）（P均＜0.01）.iPTH＞ 300ng/L组（n=242）的血磷、ALP、透析龄明显高于iPTH≤300 ng/L组（n=224）（均P＜0.01）.透析龄≥24个月组（n=228）患者的血磷[（2.70±1.49） mmol/L比（2.35±1.20） mmol/L]、血钙[（1.88±0.35） mmol/L比（2.03±0.31） mmol/L]、iPTH[（493±384） ng/L比（301±249） ng/L]、ALP值[（74.3±73.3） mmol/L比（52.0±51.0）mmol/L]与透析龄＜24个月组（n=238）比较差异均有统计学意义（均P＜0.05）.结论 该地区MHD患者存在着明显的矿物质代谢紊乱及甲状旁腺机能亢进症,透析龄长的患者及年轻透析患者高磷血症、低钙血症更为突出.