全文获取类型
收费全文 | 299篇 |
免费 | 17篇 |
国内免费 | 1篇 |
专业分类
耳鼻咽喉 | 12篇 |
儿科学 | 5篇 |
妇产科学 | 17篇 |
基础医学 | 36篇 |
口腔科学 | 7篇 |
临床医学 | 18篇 |
内科学 | 52篇 |
皮肤病学 | 5篇 |
神经病学 | 16篇 |
特种医学 | 6篇 |
外科学 | 58篇 |
综合类 | 5篇 |
一般理论 | 1篇 |
预防医学 | 22篇 |
眼科学 | 5篇 |
药学 | 32篇 |
中国医学 | 12篇 |
肿瘤学 | 8篇 |
出版年
2023年 | 3篇 |
2022年 | 13篇 |
2021年 | 14篇 |
2020年 | 14篇 |
2019年 | 19篇 |
2018年 | 13篇 |
2017年 | 13篇 |
2016年 | 13篇 |
2015年 | 9篇 |
2014年 | 20篇 |
2013年 | 20篇 |
2012年 | 28篇 |
2011年 | 22篇 |
2010年 | 7篇 |
2009年 | 13篇 |
2008年 | 16篇 |
2007年 | 11篇 |
2006年 | 16篇 |
2005年 | 7篇 |
2004年 | 8篇 |
2003年 | 5篇 |
2002年 | 6篇 |
2001年 | 1篇 |
1999年 | 1篇 |
1997年 | 1篇 |
1994年 | 2篇 |
1993年 | 1篇 |
1992年 | 1篇 |
1991年 | 2篇 |
1990年 | 1篇 |
1989年 | 3篇 |
1988年 | 4篇 |
1987年 | 2篇 |
1986年 | 2篇 |
1984年 | 1篇 |
1983年 | 2篇 |
1976年 | 1篇 |
1975年 | 1篇 |
1958年 | 1篇 |
排序方式: 共有317条查询结果,搜索用时 15 毫秒
31.
Vasospasm of RP is thought to occur in the lungs. To assess pulmonary vasospasm, we analyzed the early and late Dsb variations after a digital CPT. Sixteen normal volunteers and 20 patients (7 with primary, 13 with secondary RP) were included. A clinical RP was conducted on ten patients, nine with secondary and one with primary RP. The Dsb analysis showed: no significant variations in control subjects, a quick and short fall in primary RP significant after 15 min and a delayed fall in secondary RP significant after 45 min. A Dsb decrease was noticed even if no clinical RP occurred. The pallor phase of RP was associated with a concomitant decrease in the DCO and the hyperemic phase, with a Dsb increase. These results agree with those of previous studies with a few differences. 相似文献
32.
Dr. C. Alexandre D. Chappard F. Caulin A. Bertrand S. Palle G. Riffat 《Calcified tissue international》1988,42(6):345-350
Summary The bone histomorphometric effects of intermittent phosphate and calcitonin therapy during 1 year were analyzed in 15 involutional
osteoporotic patients. Phosphate was administered continuously (1.5 g/day) and calcitonin was injected during 5 days every
third week (50 IU/day). The bone cell response was analyzed in two separate groups, according to the amount of trabecular
bone present in the iliac bone biopsy: patients with trabecular bone volume (TBV) beyond the histomorphometric spontaneous
fracture threshold (0.16 mm3/mm3) (group 1; 11 patients) and patients with TBV above this threshold (group 2; 4 patients).
In group 1, the treatment significantly increased TBV from 0.113±0.025 to 0.156±0.046 mm3/mm3 by thickening the existing trabeculae
rather than by creating new trabeculae; stimulation of bone formation rate (+50%) and significant reduction in active trabecular
resorption surfaces (from 0.021±0.013 to 0.010±0.006 mm2/mm2;P<.05) may have led to positive bone balance. In group 2, TBV was not changed because of the treatment's relative inefficiency
for reducing the bone-resorbing cell activity, leading to likely persistent negative bone balance. Cortical thickness did
not change in either group. This study confirms the positive effectiveness of continuous treatment with phosphate and intermittent
calcitonin during 1 year on bone balance in involutional osteoporosis with low amount of bone. The lack of response in patients
with normal amount of bone must be verified before raising the hypothesis of different bone cell activity and before anticipating
the therapeutic response according to local bone mass besides bone remodeling status in osteoporosis. 相似文献
33.
34.
35.
Attar ZB Muzaffar S 《Journal of the College of Physicians and Surgeons--Pakistan : JCPSP》2006,16(3):237-238
An unusual case of congenital benign hibernoma, in the submandibular region, in a 2.5 years old girl, is reported, who presented with a progressively increasing neck swelling. A CAT scan of neck revealed a superficial and deep low density mass. Surgical excision revealed a benign hibernoma. A 3-year follow-up shows no recurrence. 相似文献
36.
37.
38.
39.
The present study was designed to evaluate the behavioral and neurochemical profiles of clozapine and risperidone in rats in a dose-dependent manner. Animals injected intraperitoneally (i.p.) with clozapine (2.5, 5.0 and 10.0 mg kg-1) or risperidone (1.0, 2.5 and 5.0 mg kg-1) were sacrificed 1 h later to collect brain samples. Hypolocomotive effects (home cage activity and catalepsy) were successively monitored in each animal after the drug or saline administration. Both drugs significantly (p < 0.01) decreased locomotor activity at high doses and in a dose-dependent manner. Maximum (100%) cataleptic potential was achieved at a high dose (5.0 mg kg-1) of risperidone. Neurochemical estimations were carried out by HPLC with electrochemical detection. Both drugs, at all doses, significantly (p < 0.01) increased the concentration of homovanillic acid (HVA), a metabolite of dopamine (DA), in the striatum. Dihydroxyphenylacetic acid (DOPAC) levels increased in the striatum and decreased in the rest of the brain, particularly in clozapine-injected rats. 5-Hydroxyindoleacetic acid (5-HIAA), the predominant metabolite of serotonin, significantly (p < 0.01) decreased in the striatum. 5-Hydroxytryptamine (5-HT) was significantly (p < 0.01) increased by risperidone and decreased by clozapine in the rest of the brain. Striatal tryptophan (TRP) was significantly (p < 0.01) decreased by risperidone and increased in the rest of the brain. The striatal HVA/DA ratio increased and the 5-HT turnover rate remained unchanged in the rest of the brain. Results suggest that the affinity of the two drugs towards D2/5-HT1A receptors interaction is involved in lower incidence of extrapyramidal side effects. Role of 5-HT1A receptors in the treatment of schizophrenia is discussed. 相似文献
40.