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951.
Xiao Tian Wijnant Sara Renata Alex van der Velpen Isabelle Terzikhan Natalie Lahousse Lies Ikram M. Kamran Vernooij Meike W. Brusselle Guy G. Ikram M. Arfan 《Journal of neurology》2022,269(8):4141-4153
Journal of Neurology - To investigate the association of chronic obstructive pulmonary disease (COPD) and Preserved Ratio Impaired Spirometry (PRISm) with cognitive performance and presence of... 相似文献
952.
Pionke-Ubych Renata Frydecka Dorota Cechnicki Andrzej Krężołek Martyna Nelson Barnaby Gawęda Łukasz 《European archives of psychiatry and clinical neuroscience》2022,272(6):1073-1085
European Archives of Psychiatry and Clinical Neuroscience - The hypothesis of the psychosis continuum enables to study the mechanisms of psychosis risk not only in clinical samples but in... 相似文献
953.
954.
Impact of de novo donor‐specific anti‐HLA antibodies on grafts outcomes in simultaneous pancreas–kidney transplantation
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Jorge Malheiro La Salete Martins Sandra Tafulo Leonídio Dias Isabel Fonseca Idalina Beirão António Castro‐Henriques António Cabrita 《Transplant international》2016,29(2):173-183
De novo donor‐specific antibodies (dDSA) relevance in simultaneous pancreas–kidney (SPK) transplantation has been scarcely investigated. We analyzed dDSA relationship with grafts outcomes in a long‐term follow‐up SPK‐transplanted cohort. In 150 patients that received SPK transplant between 2000 and 2013, post‐transplant anti‐human leukocyte antigen (HLA) antibodies were screened and identified using Luminex‐based assays in sera collected at 3, 6, and 12 months, then yearly. dDSA were detected in 22 (14.7%) patients at a median 3.1 years after transplant. Pretransplant anti‐HLA sensitization (OR = 4.64), full HLA‐DR mismatch (OR = 4.38), and previous acute cellular rejection (OR = 9.45) were significant risk factors for dDSA. dDSA were significantly associated with kidney (in association with acute rejection) and pancreas graft failure. In dDSA+ patients, those with at least one graft failure presented more frequently dDSA against class II or I + II (P = 0.011) and locusDQ (P = 0.043) and had a higher median dDSA number (P = 0.014) and strength (P = 0.030). Median time between dDSA emergence and pancreas and kidney graft failure was 5 and 12 months, respectively. Emergence of dDSA increased the risk of grafts failure in SPK‐transplanted patients. Full HLA‐DR mismatch was associated with dDSA emergence. dDSA characteristics might help identify patients at a higher risk of graft failure. 相似文献
955.
956.
Ferran Torner Josep M. Segur Rosendo Ullot Francisco Soldado Pedro Domenech Lydia DeSena Jorge Knorr 《International orthopaedics》2016,40(8):1683-1688
Purpose
The non-invasive expandable prosthesis for skeletally immature patients is used after limb salvage surgery following tumor resection. The aim of the study was to assess the effectiveness of this treatment.Methods
Seven paediatric patients with femoral tumors had resection and limb salvage with an uncemented non-invasive growing prosthesis. Mean age at the time of surgery was 9.8 (range 8–12) years. There were six distal femur osteosarcomas and one proximal femur Ewing sarcoma. Six total knee prosthesis were implanted at the time of primary tumor resection and one bipolar hip prosthesis was a revision from a failed osteoarticular hip allograft. Functional outcomes and emotional acceptance were assessed using the MSTS score.Results
The mean follow-up was 65.3 months (range 29–91) months. Two patients died of pulmonary metastasis and there was no local recurrence. The mean femoral resection was 18 cm (range 17–19) on the knee, and 24 cm on the hip. Mean total expansion was 36.4 mm (range 12.3–63.5). The mean MSTS score after rehabilitation was 26.3 (range 21–29). There was one lengthening device failure, one late infection and one patient who required iliofemoral bypass grafting surgery for a pelvic metastasis. No local recurrence occurred.Conclusions
The non-invasive expandable prosthesis reduces the final limb-length discrepancy in growing patients with an acceptable function and appears to have an advantage as compared to invasive expandable prostheses which require multiple surgical procedures, but the complications rate is still high.957.
958.
Jaime Alfaro Javier Guzmán Catalina García David Sirlopú Fernando Reyes Jorge Varela 《Child indicators research》2016,9(3):731-742
Child and adolescent measures of the quality of life or subjective well-being are scarce in Latin American countries. Chile is no exception to this situation that represents a gap in the literature for South American countries research. Thus, the aim was to analyze the psychometric properties of the Personal Well-being Index for School Children (PWI-SC) of Cummins et al. Social Indicators Research, 64(2), 159–190, (2003) in a sample of Chilean school children. We use a sample of 1096 pupils between 10 and 12 years old (M?=?11.03; SD?=?0.89) and residents of three major Chilean cities. Results of Exploratory and Confirmatory Factor Analysis provided evidence for only one single factor solution. Moreover, an acceptable level of internal reliability was observed (α?=?0.77). The discussion of results considers other internationals applications of PWI-SC. 相似文献
959.
Salim Demétrio Jorge Neto Jackeline Souza Rangel Machado Ana Carolina Tavares Palei Wellington Paula Martins Valéria Cristina Sandrim 《The journal of maternal-fetal & neonatal medicine》2016,29(20):3406-3409
Objective: The objective was to evaluate and compare the whole blood nitrite concentration in the three trimesters of pregnancy. Additionally, we investigate whether there is any relation between nitrite concentrations and Doppler ultrasound analysis of some maternal and fetal vessels.Methods: Thirty-three healthy pregnant women were examined at the first (11–14 weeks), second (20–24 weeks) and third trimester (34–36 weeks) of pregnancy. In the three exams, we determined the maternal whole blood nitrite concentration and uterine arteries Doppler analysis to determine pulsatility index (PI), and resistance index (RI). In the second and third trimester we also performed fetal umbilical and middle cerebral arteries PI and RI. We compared the concentrations of nitrite in three trimesters and correlated with Doppler parameters.Results: No difference was observed in the whole blood nitrite concentrations across trimesters: 151.70?±?77.90?nmol/ml, 142.10?±?73.50?nmol/ml and 147.10?±?87.30?nmol/ml; first, second and third trimesters, respectively. We found no difference in correlation between whole blood nitrite concentration and Doppler parameters from the evaluated vessels.Conclusions: In healthy pregnant women, the nitrite concentrations did not change across gestational trimesters and there was also no strong correlation with Doppler impedance indices from maternal uterine arteries and fetal umbilical and middle cerebral arteries. 相似文献
960.
Mediastinal Germ Cell Tumors in Pediatric Patients: A Report From the Italian Association of Pediatric Hematology and Oncology
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