全文获取类型
收费全文 | 22463篇 |
免费 | 1778篇 |
国内免费 | 32篇 |
专业分类
耳鼻咽喉 | 172篇 |
儿科学 | 749篇 |
妇产科学 | 615篇 |
基础医学 | 2972篇 |
口腔科学 | 239篇 |
临床医学 | 2909篇 |
内科学 | 4138篇 |
皮肤病学 | 277篇 |
神经病学 | 2227篇 |
特种医学 | 435篇 |
外科学 | 2253篇 |
综合类 | 378篇 |
一般理论 | 81篇 |
预防医学 | 3387篇 |
眼科学 | 241篇 |
药学 | 1296篇 |
中国医学 | 17篇 |
肿瘤学 | 1887篇 |
出版年
2024年 | 32篇 |
2023年 | 276篇 |
2022年 | 373篇 |
2021年 | 969篇 |
2020年 | 609篇 |
2019年 | 926篇 |
2018年 | 931篇 |
2017年 | 694篇 |
2016年 | 741篇 |
2015年 | 766篇 |
2014年 | 991篇 |
2013年 | 1359篇 |
2012年 | 2082篇 |
2011年 | 2010篇 |
2010年 | 1054篇 |
2009年 | 849篇 |
2008年 | 1492篇 |
2007年 | 1407篇 |
2006年 | 1398篇 |
2005年 | 1272篇 |
2004年 | 1100篇 |
2003年 | 907篇 |
2002年 | 794篇 |
2001年 | 105篇 |
2000年 | 101篇 |
1999年 | 120篇 |
1998年 | 172篇 |
1997年 | 98篇 |
1996年 | 72篇 |
1995年 | 62篇 |
1994年 | 41篇 |
1993年 | 50篇 |
1992年 | 30篇 |
1991年 | 27篇 |
1990年 | 30篇 |
1989年 | 18篇 |
1988年 | 19篇 |
1987年 | 19篇 |
1986年 | 17篇 |
1985年 | 28篇 |
1984年 | 29篇 |
1983年 | 23篇 |
1982年 | 29篇 |
1981年 | 38篇 |
1980年 | 17篇 |
1979年 | 10篇 |
1978年 | 14篇 |
1977年 | 10篇 |
1975年 | 8篇 |
1928年 | 5篇 |
排序方式: 共有10000条查询结果,搜索用时 36 毫秒
991.
The natural history and survival of children with fibrocystic liver–kidney disease undergoing solid organ transplantation have infrequently been described. We report outcomes in a cohort of US children with fibrocystic liver–kidney disease receiving solid organ transplants over 20 yr. Retrospective cohort study of pediatric transplant recipients with diagnoses of fibrocystic liver–kidney disease from 1/1990 to 3/2010, using data from the SRTR. Subjects were categorized by the first transplanted organ: LT, KT, or SLK. Primary outcomes were death, re‐transplant, transplant of the alternate organ, or initiation of dialysis. Seven hundred and sixteen subjects were transplanted in this period. Median age at first transplant was 9.7 yr. Of the LT, 14 (19%) required a second liver transplant at median of 0.2 yr, and five (7%) required kidney transplant or dialysis at a median of 9.0 yr. Of the KT, 188 (31%) required a second kidney transplant or dialysis at a median of 5.9 yr. Twenty‐nine (5%) subsequently received liver transplant at a median of 6.0 yr. Among patients in this registry, far more children underwent kidney than liver transplants. The risk of subsequently needing transplantation of an alternate organ was low. 相似文献
992.
993.
994.
995.
996.
Alexander A. Boucher Leah Rosenfeldt Duaa Mureb Jessica Shafer Bal Krishan Sharma Adam Lane Rebecca R. Crowther Melanie C. McKell Jordan Whitt Theresa Alenghat Joseph Qualls Silvio Antoniak Nigel Mackman Matthew J. Flick Kris A. Steinbrecher Joseph S. Palumbo 《Journal of thrombosis and haemostasis》2020,18(1):91-103
997.
998.
999.
Anastassios C. Koumbourlis Etsuro K. Motoyama Rebecca L. Mutich George B. Mallory Stephen A. Walczak Kathleen Fertal 《Pediatric pulmonology》1996,21(1):28-34
We investigated whether early lung function abnormalities in prematurely born children with a history of chronic lung disease improve in late childhood and adolescence. We performed a prospective, longitudinal evaluations of pulmonary function over an 8 year period. In seventeen patients from the age (mean ± SD) of 8.2 ± 1.2 years to the age of 15.1 ± 1.6 years. They had been born at 29.1 ± 1.9 weeks of gestation, with a birthweight of 1120 ± 190 g, and they had received supplemental oxygen, with or without mechanical ventilation, for 40.4 ± 23.8 days during the neonatal period. They all had radiographic evidence of chronic lung disease at 4 weeks of age. Annual measurements of lung volumes using the helium dilution technique, and of airway function with spirometry and maximal expiratory flow-volume curves over a 5 to 8 year period, were obtained. The results indicated that total lung capacity (TLC) and vital capacity (VC) were within the predicted normal range in all patients and increased over time. In contrast, the initially abnormal residual volume (RV) and RV/TLC ratio decreased over time, suggesting gradual resolution of air-trapping. The peak expiratory flow rate (PEFR), forced expiratory volume in 1 second (FEV1), and the ratio FEV1/FVC remained at or above the predicted normal range in all patients. FEF25–75, FEF50, and FEF75 were within normal limits in eight patients and abnormally low (more than 2 SD below the predicted normal value) in the remaining nine patients, indicating small airway obstruction. Eight of the nine patients with lower airway obstruction showed significant response to inhaled bronchodilator, and four responded to a histamine challenge. None of the eight patients with normal airway function responded to histamine, but four responded to bronchodilators. The perinatal history, family history of asthma, and exposure to smoking were similar in patients with and without airway obstruction. The height and weight were and remained within the normal range. We conclude that gradual normalization of air-trapping continues well into adolescence in virtually all patients with a history of prematurity and chronic lung disease. In contrast, airflow obstruction may persist but does not get worse later in life. Although chronic airflow obstruction probably is the consequence of injury to the small airways during the neonatal period, it is present in only some of the children, and it does not appear to be directly related to the perinatal history. Finally, there is evidence that airway hyperresponsiveness may be a contributing factor to the development and/or persistence of airflow obstruction in chronic lung disease of prematurity. Pediatr Pulmonol. 1996; 21:28–34 . © 1996 Wiley-Liss, Inc. 相似文献
1000.
Robin Fuchs-Young Susan Howe Laura Hale Rebecca Miles Cheryl Walker 《Molecular carcinogenesis》1996,17(3):151-159
Uterine leiomyoma is the most frequent gynecologic neoplasm in women. By using a panel of cell lines derived from spontaneous Eker rat leiomyomas, we examined the estrogen-responsive phenotype of these tumor cells. Leiomyoma-derived ELT cell lines proliferated in response to estrogen, and estrogen-induced cell proliferation could be inhibited by the estrogen antagonist ICI 182780 and the selective estrogen-receptor modulators (SERMs) raloxifene and tamoxifen. In addition to inhibiting cell growth, these antagonists also inhibited estrogen-induced increases in progesterone-receptor expression. These data indicate that SERMs such as raloxifene and tamoxifen act as estrogen antagonists in uterine myometrial cells and suggest that this class of compounds may be effective for treatment of this important gynecologic neoplasm. © 1996 Wiley-Liss, Inc. 相似文献