全文获取类型
收费全文 | 1986篇 |
免费 | 149篇 |
国内免费 | 32篇 |
专业分类
耳鼻咽喉 | 6篇 |
儿科学 | 96篇 |
妇产科学 | 31篇 |
基础医学 | 282篇 |
口腔科学 | 43篇 |
临床医学 | 140篇 |
内科学 | 437篇 |
皮肤病学 | 93篇 |
神经病学 | 80篇 |
特种医学 | 203篇 |
外科学 | 186篇 |
综合类 | 145篇 |
预防医学 | 118篇 |
眼科学 | 14篇 |
药学 | 169篇 |
1篇 | |
中国医学 | 14篇 |
肿瘤学 | 109篇 |
出版年
2023年 | 10篇 |
2022年 | 13篇 |
2021年 | 28篇 |
2020年 | 26篇 |
2019年 | 29篇 |
2018年 | 50篇 |
2017年 | 32篇 |
2016年 | 32篇 |
2015年 | 34篇 |
2014年 | 52篇 |
2013年 | 93篇 |
2012年 | 91篇 |
2011年 | 95篇 |
2010年 | 68篇 |
2009年 | 76篇 |
2008年 | 97篇 |
2007年 | 108篇 |
2006年 | 84篇 |
2005年 | 63篇 |
2004年 | 57篇 |
2003年 | 50篇 |
2002年 | 34篇 |
2001年 | 42篇 |
2000年 | 37篇 |
1999年 | 40篇 |
1998年 | 61篇 |
1997年 | 52篇 |
1996年 | 57篇 |
1995年 | 41篇 |
1994年 | 27篇 |
1993年 | 32篇 |
1992年 | 39篇 |
1991年 | 39篇 |
1990年 | 29篇 |
1989年 | 44篇 |
1988年 | 37篇 |
1987年 | 26篇 |
1986年 | 32篇 |
1985年 | 36篇 |
1984年 | 20篇 |
1983年 | 15篇 |
1982年 | 26篇 |
1981年 | 25篇 |
1980年 | 16篇 |
1979年 | 12篇 |
1978年 | 18篇 |
1977年 | 26篇 |
1976年 | 24篇 |
1975年 | 15篇 |
1974年 | 13篇 |
排序方式: 共有2167条查询结果,搜索用时 0 毫秒
51.
52.
Preethi Jeyaraman Narendra Agrawal Rahul Bhargava Divya Bansal Rayaz Ahmed Dinesh Bhurani Sachin Bansal Neha Rastogi Pronamee Borah Rahul Naithani 《Transfusion and apheresis science》2021,60(3):103075
BackgroundData on convalescent plasma therapy (CPT) in patients of hematological malignancies with severe Covid-19 is scarce.ObjectiveTo study 14-day mortality in patients who received CPT.Patients & methodsRetrospective multicentre observational study conducted in 4 centres treating haematological malignancies across Delhi-national capital region. Total 33 haematological malignancies patients with severe Covid-19 who received CPT were analysed.ResultsThe median age of the study cohort was 62 years (18–80 years). Twenty one percent patients had 1 comorbidity, 18 % had 2 comorbidities and 6% patients had 3 and 5 comorbidities each. Twenty four patients were on active therapy. Sixty nine percent of patients required ICU stay. Twenty five patients received plasma therapy within 7 days (early) of diagnosis of Covid-19 infection. Median day of plasma infusion from date of diagnosis of Covid-19 infection was 4 days (range: 2–25 days). Patient who had early initiation of plasma therapy had shorter duration of hospitalisation (12.7 vs 24.3 days, p = 0.000). Overall mortality in the cohort was 45.5%. There was no effect of disease status, active therapy, presence of comorbidity on mortality. There was no difference in the mortality in patients receiving early vs late initiation of plasma therapy or in patients receiving one versus two plasma therapy.ConclusionsWe provide a large series of patients with hematological malignancies and role of CPT in this group. 相似文献
53.
54.
Sera from twenty six patients of various types of leprosy were tested for the detection of circulating auto-antibodies and nuclear components against thyroid using various methods. Four patients of lepromatous leprosy had higher levels of thyroid auto-antibodies by latex agglutination. Three patients showed the presence of anti-nuclear antibodies, two belonged to the TT and one to the LL group. 相似文献
55.
56.
57.
Ram B. Singh Gurpreet S. Wander Amit Rastogi Pradeep K. Shukla Adarsh Mittal Jagdish P. Sharma Shiv K. Mehrotra Raj Kapoor Raj K. Chopra 《Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy》1998,12(4):347-353
The effects of oral treatment with coenzyme Q10 (120 mg/d) were compared for 28 days in 73 (intervention group A) and 71 (placebo group B) patients with acute myocardial infarction (AMI). After treatment, angina pectoris (9.5 vs. 28.1), total arrhythmias (9.5% vs. 25.3%), and poor left ventricular function (8.2% vs. 22.5%) were significantly (P < 0.05) reduced in the coenzyme Q group than placebo group. Total cardiac events, including cardiac deaths and nonfatal infarction, were also significantly reduced in the coenzyme Q10 group compared with the placebo group (15.0% vs. 30.9%, P < 0.02). The extent of cardiac disease, elevation in cardiac enzymes, and oxidative stress at entry to the study were comparable between the two groups. Lipid peroxides, diene conjugates, and malondialdehyde, which are indicators of oxidative stress, showed a greater reduction in the treatment group than in the placebo group. The antioxidants vitamin A, E, and C and beta-carotene, which were lower initially after AMI, increased more in the coenzyme Q10 group than in the placebo group. These findings suggest that coenzyme Q10 can provide rapid protective effects in patients with AMI if administered within 3 days of the onset of symptoms. More studies in a larger number of patients and long-term follow-up are needed to confirm our results. 相似文献
58.
59.
60.
Viganego F O'Donoghue S Eldadah Z Shah MH Rastogi M Mazel JA Platia EV 《The American journal of cardiology》2012,109(10):1466-1471
Cardiac device infections (CDIs) represent a serious complication after the implantation of pacemakers and defibrillators. In addition to antimicrobials, complete hardware removal, mostly with percutaneous lead extraction (PLE), is necessary to limit recurrences. However, CDI diagnosis is often difficult and is sometimes delayed, and scarce data exist on how the timing of PLE may affect clinical outcomes. In this study, the in-hospital outcomes of 52 consecutive patients with CDIs who underwent PLE were retrospectively analyze. Co-morbidities such as diabetes mellitus, congestive heart failure, renal insufficiency, and end-stage renal disease were highly prevalent in the study cohort. Patients were divided into group A (bacteremia or device endocarditis) and group B (localized pocket infection). In-hospital mortality was 29% in group A and 5% in group B (p = 0.02) and was due mostly to sepsis. Hospital stays were shorter in group B patients (5.7 vs 21.7 days, p <0.001). Presentation with hypotension was more commonly observed in group A patients and was associated with higher in-hospital mortality, whereas pocket findings correlated with better survival. Postoperative courses after PLE were uneventful in most patients, and no fatal complications were observed. PLE was performed significantly earlier in group B patients (hospitalization day 1.3 vs 7.6, p <0.001). PLE performed within 3 hospitalization days was associated with lower in-hospital mortality (p = 0.01). In conclusion, PLE performed within 3 days from admission is associated with shorter hospitalization and better survival. A timely diagnosis is crucial, particularly in the absence of local findings, because early treatment with PLE is likely to prevent the catastrophic outcomes of unrelenting CDIs. 相似文献