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排序方式: 共有449条查询结果,搜索用时 15 毫秒
81.
Kishanchand Chethan Seetharam Prasad Lingadakai Ramachandra 《The Canadian Journal of Infectious Diseases & Medical Microbiology》2012,23(3):e65-e66
Mucormycosis is a relatively uncommon, aggressive and lethal mycosis. Fungi from the order Mucorales are the etiological agents of mucormycosis. The condition is more common among the immunocompromised, diabetic patients with ketoacidosis and people with iron overload syndromes. Diagnosis of mucormycosis requires a high index of suspicion regarding the possibility of the condition in high-risk individuals. Timely diagnosis is critical to survival and minimization of morbidity. A favourable outcome is possible only if appropriate treatment is initiated as early as possible. The present article reports a case of ileocolic mucormycosis involving a patient with chronic renal failure and familial hyperuricemia. 相似文献
82.
83.
Harsha Aramada Ramachandra Reddy Aramada 《Indian Journal of Thoracic and Cardiovascular Surgery》2010,26(1):43-45
The existing non-surgical treatments for empyema failed to produce desirable results in this case. Irrigating the pleural cavity with antibiotics (clagget and modified clagget) did not offer a cure. Completely filling the pleural cavity with antibiotic solution and clamping the chest-tube for 8 days-a simple unconventional treatment-cured empyema in this patient. 相似文献
84.
Volynskaya Z Haka AS Bechtel KL Fitzmaurice M Shenk R Wang N Nazemi J Dasari RR Feld MS 《Journal of biomedical optics》2008,13(2):024012
Using diffuse reflectance spectroscopy and intrinsic fluorescence spectroscopy, we have developed an algorithm that successfully classifies normal breast tissue, fibrocystic change, fibroadenoma, and infiltrating ductal carcinoma in terms of physically meaningful parameters. We acquire 202 spectra from 104 sites in freshly excised breast biopsies from 17 patients within 30 min of surgical excision. The broadband diffuse reflectance and fluorescence spectra are collected via a portable clinical spectrometer and specially designed optical fiber probe. The diffuse reflectance spectra are fit using modified diffusion theory to extract absorption and scattering tissue parameters. Intrinsic fluorescence spectra are extracted from the combined fluorescence and diffuse reflectance spectra and analyzed using multivariate curve resolution. Spectroscopy results are compared to pathology diagnoses, and diagnostic algorithms are developed based on parameters obtained via logistic regression with cross-validation. The sensitivity, specificity, positive predictive value, negative predictive value, and overall diagnostic accuracy (total efficiency) of the algorithm are 100, 96, 69, 100, and 91%, respectively. All invasive breast cancer specimens are correctly diagnosed. The combination of diffuse reflectance spectroscopy and intrinsic fluorescence spectroscopy yields promising results for discrimination of breast cancer from benign breast lesions and warrants a prospective clinical study. 相似文献
85.
BACKGROUND: Congenital heart diseases (CHDs) are the commonest single group of congenital abnormalities with a prevalence ranging from 1.0 to 50.89 per 1000 live births in the world population including India, whereas Mysore has a prevalence of 11.08 per 1000 live births. One of the risk factors for the occurrence of CHDs is parental consanguinity, in particular first-cousin marriage between parents. AIM: The present study examined the role of consanguineous marriages in causing CHDs in Mysore, South India. SUBJECTS AND METHODS: A total of 144 confirmed CHD cases with an age range of 1 day to 23 years and a control group of 200 families from different localities of Mysore city were considered for the present study. Methods included the establishment of a genetic register and pedigree analysis followed by statistical analysis by logistic regression. RESULTS: The findings revealed that first-cousin marriages (44.68%) and uncle-niece marriages (46.81%) are equally significant in increasing CHDs. The subtypes of CHDs associated with consanguinity were found to be atrial septal defect (ASD) and patent ductus arteriosus (PDA). These findings emphasize the important role played by segregation of recessive genes in the offspring resulting in the causation of CHDs. CONCLUSION: Therefore, for every incidence of parental consanguinity, the risk (odds) of birth of a child with CHD increases. There is an urgent need to educate the public on the deleterious effects of inbreeding, especially in India, which has high overall consanguinity. 相似文献
86.
87.
P. S. Arunachalam C. R. S. Ramachandra 《Indian journal of otolaryngology and head and neck surgery》2000,52(3):297-299
Squamous cell carcinomas of the parotid gland are very rare. Majority of them will be metastatic with primaries in the head
and neck. Very rarely, they can be from unknown primaries or primary parotid tumor itself. We present a case of the Squamous
cell carcinoma with extensive local spread to the scalp, skin of the face, parapharyngeal space and causing occlusion of the
internal carotid artery. Brief review of literature regarding primary and secondary type of these tumors is also included.
Key words: Squamous cell carcinoma, parotid tumors. 相似文献
88.
Ramachandra V Phuc S Franco AC Gonzales RA 《Alcoholism, clinical and experimental research》2007,31(10):1669-1676
BACKGROUND: The C57BL/6 mouse model has been used extensively in alcohol drinking studies, yet significant differences in ethanol preference between substrains exist. Differences in ethanol-induced dopamine release in the ventral striatum could contribute to this variability in drinking behavior as dopamine has been implicated in the reinforcing properties of ethanol. METHODS: A 2-bottle choice experiment investigated the difference in ethanol preference between C57BL/6J and C57BL/6NCrl animals. Microdialysis was used to determine dopamine release and ethanol clearance in these 2 substrains after intraperitoneal injections of 1.0, 2.0 and 3.0 g/kg ethanol or saline. RESULTS: C57BL/6J mice exhibited significantly greater ethanol preference and less ethanol-stimulated dopamine release compared with C57BL/6NCrl mice. The intraperitoneal injections of ethanol caused a significant increase in dopamine in both substrains at all 3 doses with significant differences between substrains at the 2 highest alcohol doses. Saline injections had a significant effect on dopamine release when given in a volume equivalent to the 3 g/kg ethanol dose. Ethanol pharmacokinetics were similar in the 2 substrains at all 3 doses. CONCLUSIONS: Ethanol-induced dopamine release in the ventral striatum may contribute to the differences in alcohol preference between C57BL/6J and C57BL/6NCrl mice. 相似文献
89.
Venkata Satya Suresh Attili Hemant K. Dadhich Clementeena RamaRao P. P. Bapsy C. Ramachandra G. Anupama 《The Indian journal of surgery》2007,69(5):201-202
Primary rhabdomyosarcoma of the breast is a rarely reported in adults, and it occurrence is mostly observed in children. We
report a case of primary rhabdomyosarcoma of breast in a 40-year-old lady, who presented in early stage and is in complete
remission after one year of treatment. 相似文献
90.
Arehalli S. Manjappa Peeyush N. Goel Makam P. Vekataraju Kesarla S. Rajesh Kinjal Makwana Mukesh Ukawala Yuvraj Nikam Rajiv P. Gude Rayasa S. Ramachandra Murthy 《Pharmaceutical research》2013,30(10):2675-2693