首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   2575951篇
  免费   212991篇
  国内免费   7681篇
耳鼻咽喉   34507篇
儿科学   84903篇
妇产科学   72196篇
基础医学   360558篇
口腔科学   74588篇
临床医学   231302篇
内科学   512909篇
皮肤病学   58515篇
神经病学   211383篇
特种医学   104348篇
外国民族医学   720篇
外科学   396042篇
综合类   63514篇
现状与发展   5篇
一般理论   912篇
预防医学   205469篇
眼科学   57418篇
药学   187880篇
  8篇
中国医学   4587篇
肿瘤学   134859篇
  2018年   25050篇
  2016年   22802篇
  2015年   26021篇
  2014年   36157篇
  2013年   54777篇
  2012年   70247篇
  2011年   74793篇
  2010年   45572篇
  2009年   43940篇
  2008年   70831篇
  2007年   75137篇
  2006年   76655篇
  2005年   74318篇
  2004年   72199篇
  2003年   69681篇
  2002年   67172篇
  2001年   120183篇
  2000年   123876篇
  1999年   104364篇
  1998年   30405篇
  1997年   27467篇
  1996年   28115篇
  1995年   27834篇
  1994年   26152篇
  1993年   24575篇
  1992年   86979篇
  1991年   84754篇
  1990年   82075篇
  1989年   78981篇
  1988年   73472篇
  1987年   72356篇
  1986年   68538篇
  1985年   66264篇
  1984年   50231篇
  1983年   42805篇
  1982年   26066篇
  1981年   23417篇
  1980年   22068篇
  1979年   46906篇
  1978年   33319篇
  1977年   28194篇
  1976年   26233篇
  1975年   27652篇
  1974年   33310篇
  1973年   32017篇
  1972年   29487篇
  1971年   27573篇
  1970年   25309篇
  1969年   23773篇
  1968年   21859篇
排序方式: 共有10000条查询结果,搜索用时 31 毫秒
81.
82.
83.
84.
85.
86.
The current situation in which the humanities are disparaged affects all university disciplines, including nursing, in whose historical evolution the humanities have always been present in one form or another. Looking beyond this disrepute, this study proposes that nursing renew its attention to classical philosophy. Specifically, it invites a close reading of Xenophon's Anabasis and Plato's Meno, to get three related goals: to show how the use of ancient texts are very valuable tools for the philosophical initiation of nursing students and can help them reflect on their choice of nursing as a practical activity; to reflect on the problem of virtue and the nature of the good life; and to show how the interaction with ancient texts allows students to reflect on questions and issues of life, theirs and others, that are not open to investigation through a purely scientific method. Consequently, both Anabasis and Meno readings strengthen the intellectual relationship between philosophy and nursing, enabling the latter to delve deeper into the key questions of its own thought as a discipline.  相似文献   
87.
Obesity Surgery - Laparoscopic sleeve gastrectomy (LSG) is increasingly playing a key role in obesity management. Such operations, however, carry complications sometimes including leaks. The...  相似文献   
88.
Lasers in Medical Science - Studies reported the harmful effects of 2,4-D on body tissues, provoking changes in the anatomy and physiology of the kidneys, liver, and testicles. Thus, the objective...  相似文献   
89.
90.

Background

Resistin is an immunometabolic mediator that is elevated in several inflammatory disorders. A ligand for Toll-like receptor 4, resistin modulates the recruitment and activation of myeloid cells, notably neutrophils. Neutrophils are major drivers of cystic fibrosis (CF) lung disease, in part due to the release of human neutrophil elastase- and myeloperoxidase-rich primary granules, leading to tissue damage. Here we assessed the relationship of resistin to CF lung disease.

Methods

Resistin levels were measured in plasma and sputum from three retrospective CF cohorts spanning a wide range of disease. We also assessed the ability of neutrophils to secrete resistin upon activation in vitro. Finally, we constructed a multivariate model assessing the relationship between resistin levels and lung function.

Results

Plasma resistin levels were only marginally higher in CF than in healthy control subjects. By contrast, sputum resistin levels were very high in CF, reaching 50–100 fold higher levels than in plasma. Among CF patients, higher plasma resistin levels were associated with allergic bronchopulmonary aspergillosis, and higher sputum resistin levels were associated with CF-related diabetes. Mechanistically, in vitro release of neutrophil primary granules was concomitant with resistin secretion. Overall, sputum resistin levels were negatively correlated with CF lung function, independently of other variables (age, sex, and genotype).

Conclusions

Our data establish relationships between resistin levels in the plasma and sputum of CF patients that correlate with disease status, and identify resistin as a novel mechanistic link between neutrophilic inflammation and lung disease in CF.  相似文献   
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号