全文获取类型
收费全文 | 474篇 |
免费 | 26篇 |
国内免费 | 4篇 |
专业分类
耳鼻咽喉 | 4篇 |
儿科学 | 6篇 |
妇产科学 | 10篇 |
基础医学 | 52篇 |
口腔科学 | 2篇 |
临床医学 | 41篇 |
内科学 | 114篇 |
皮肤病学 | 10篇 |
神经病学 | 33篇 |
特种医学 | 12篇 |
外科学 | 91篇 |
综合类 | 12篇 |
预防医学 | 47篇 |
眼科学 | 2篇 |
药学 | 48篇 |
中国医学 | 12篇 |
肿瘤学 | 8篇 |
出版年
2024年 | 1篇 |
2023年 | 2篇 |
2022年 | 21篇 |
2021年 | 29篇 |
2020年 | 22篇 |
2019年 | 19篇 |
2018年 | 17篇 |
2017年 | 12篇 |
2016年 | 21篇 |
2015年 | 13篇 |
2014年 | 21篇 |
2013年 | 18篇 |
2012年 | 36篇 |
2011年 | 22篇 |
2010年 | 15篇 |
2009年 | 14篇 |
2008年 | 20篇 |
2007年 | 18篇 |
2006年 | 35篇 |
2005年 | 21篇 |
2004年 | 19篇 |
2003年 | 20篇 |
2002年 | 7篇 |
2001年 | 8篇 |
2000年 | 15篇 |
1999年 | 10篇 |
1998年 | 4篇 |
1997年 | 3篇 |
1996年 | 5篇 |
1995年 | 4篇 |
1994年 | 2篇 |
1993年 | 1篇 |
1992年 | 3篇 |
1991年 | 4篇 |
1990年 | 2篇 |
1989年 | 2篇 |
1988年 | 1篇 |
1987年 | 4篇 |
1986年 | 1篇 |
1985年 | 1篇 |
1984年 | 1篇 |
1983年 | 1篇 |
1979年 | 2篇 |
1976年 | 1篇 |
1975年 | 1篇 |
1973年 | 1篇 |
1972年 | 1篇 |
1968年 | 1篇 |
1965年 | 1篇 |
1933年 | 1篇 |
排序方式: 共有504条查询结果,搜索用时 46 毫秒
11.
12.
Y Alade D Tunkel K Schulze J McGready G Jallo M Ain T Yost J Hoover‐Fong 《Clinical genetics》2013,84(3):237-243
Short stature skeletal dysplasia (SD) patients have orthopedic and neurologic complications causing significant pain and physical disability. We conducted a large cross‐sectional online survey in 361 people with short stature SD (>10 years) to describe pain prevalence, characteristics, and the relationship between pain and function. Chronic pain prevalence per Brief Pain Inventory (BPI) was 70.3%. Women reported more pain than men (73% vs 63% p = 0.04). Pain Severity Score (average of current, worst, least and average pain) averaged 3.3 ± 2, while the Pain Interference Score (with daily activities) averaged 3.4 ± 2.7 on a 10‐point scale. Per Bleck scale, 20.5% had little or no functional capacity. Increasing age and decreased ambulation independently predicted chronic pain. Chronic pain is prevalent in short stature SD patients and associated with poor physical function. Further study is required to clarify the temporal relationship among pain, function and treatments. 相似文献
13.
14.
Meenakshi Lallar Haq ul Anam Rajesh Nandal Sunder Pal Singh Surabhi Katyal 《Journal of obstetrics and gynaecology of India》2015,65(1):17-22
Objectives
To compare intravenous paracetamol and intramuscular tramadol as labor analgesics.Methods
This prospective-randomized study conducted in 200 primigravidae in active labor, distributed into two groups of 100 women each with one receiving intravenous 1,000 mg Paracetamol and other 100 mg intramuscular tramadol. Pain intensity is recorded by McGills scale before, one and 3 h after drug administration. Perinatal outcome is recorded.Results
No difference in pain intensity is seen before drug administration. After 1 h of drug administration, in paracetamol group, 4 % women had horrible pain, and 29 % had distressing pain, while in tramadol group, 30 % women had horrible pain, and 60 % had distressing pain. After 3 h of drug administration, in paracetamol group, 26 % had distressing pain, while in tramadol group, 51 % women had horrible pain, and 35 % had distressing pain. Labor duration in paracetamol and tramadol group was 4.3 and 5.9 h, respectively. In paracetamol group, nausea is seen in 2.2 % and vomiting in 1.1 %, while in tramadol group, nausea is seen in 6.4 % and vomiting in 4.3 %.Conclusions
Intravenous paracetamol is more effective labor analgesic with fewer maternal adverse effects and shortens labor as compared to intramuscular tramadol.15.
Camli Adil Teoman Ayd?n ?zgür Ta?p?nar Huriye K?z?ltan Ali Hikmet Eri? Ilknur Turk Hocaoglu Sevde Po?ul Muge Kepekci Ebru Denizli Mustafa Güler 《Journal of Physical Therapy Science》2015,27(1):179-182
[Purpose] Diabetes mellitus is a metabolic disorder resulting from a defect in insulin
secretion, insulin action, or both. A consequence of this is chronic hyperglycemia with
disturbances in carbohydrate, fat and protein metabolism. We investigated whether there is
any difference among DM patients and a control group in terms of lumbar and femur BMD
(bone mineral density), and standard deviation scores (Z score and T score). [Subjects and
Methods] This randomized, prospective, controlled, single-blind study was conducted in the
Physical Medicine and Rehabilitation Department Faculty of Medicine, Bezm-i Alem Vakıf
University. Patients with type 2 diabetes mellitus were included in the patient groups.
Healthy individuals were included in the control group. [Results] A total of 126 patients
completed the study (63 in the study group, 63 in the control group). There was no
significant difference in the results of the laboratory examinations of the cases. The
bone mineral densities of the cases were found to be significantly low in terms of the
lumbar (L1–4) T scores in the type 2 diabetes group. [Conclusion] Although osteoporosis is
one of the potential complications of type 1 diabetes, its effect on bone mineral density
in type 2 DM is controversial. In different studies, the bone mineral density values have
increased, decreased or remained normal. With the exception of the lumbar (L1–4) T score,
similar results were obtained in this study.Key words: Type 2 diabetes mellitus, Osteoporosis, Bone mineral density 相似文献
16.
Jonklaas J Nogueras-Gonzalez G Munsell M Litofsky D Ain KB Bigos ST Brierley JD Cooper DS Haugen BR Ladenson PW Magner J Robbins J Ross DS Skarulis MC Steward DL Maxon HR Sherman SI;National Thyroid Cancer Treatment Cooperative Study Group 《The Journal of clinical endocrinology and metabolism》2012,97(6):E878-E887
17.
Kuyumcu ME Yesil Y Oztürk ZA Cınar E Kızılarslanoglu C Halil M Ulger Z Yesil NK Cankurtaran M Arıoğul S 《Archives of gerontology and geriatrics》2012,55(3):739-743
Previous studies showed oxidative stress had an important impact on osteoclastic and osteoblastic functions. Oxidative stress or low levels of antioxidants are supposed to reduce BMD and cause osteoporosis. hcy, gamma glutamyltransferase (GGT), uric acid, albumin and total bilirubin are simple laboratory parameters that are related with oxidative stress. In this study we compare the serum hcy and antioxidant levels in patients with osteoporosis, osteopenia and control subjects. A total of 2190 elderly persons (1348 patients with osteoporosis, 643 patients with osteopenia and 199 control subjects) who were referred to the outpatient clinic of the Department of Internal Medicine, Division of Geriatric Medicine at Hacettepe University Hospital for comprehensive geriatric assessment were included in this cross-sectional study. Mean age of subjects were 72.30±6.34 in osteoporosis group, 71.92±6.90 in osteopenia and 71.86±5.88 in control group (p: 0.260). Multivariate regression analysis revealed that hypertension (HT) (OR: 0.675, 95% CI: 0.534-0.854, p: 0.001), diabetes mellitus (DM) (OR: 1.669, 95% CI: 1.301-2.142, p: <0.001), age (OR: 1.025, 95% CI: 1.006-1.044, p: 0.009), male gender (OR: 0.451, 95% CI: 0.358-0.569, p<0.001), uric acid (OR: 0.893, 95% CI: 0.837-0.952, p: 0.001), hcy (OR: 1.042, 95% CI: 1.023-1.061, p<0.001), albumin (OR: 0.521, 95% CI: 0.376-0.724, p<0.001), GGT (OR: 1.010, 95% CI: 1.003-1.017, p: 0.003), creatinine (OR: 0.630, 95% CI: 0.459-0.864, p: 0.004) were independent variables predicting the occurrence of osteoporosis. This study shows there is an imbalance between natural antioxidative and oxidative markers in patients with osteoporosis. Higher serum uric acid and albumin levels are associated with a lower prevalence of osteoporosis whereas higher hcy and GGT levels are associated lower BMD and higher osteoporosis prevalence. 相似文献
18.
Histopathology of surgically treated renal tumours in young adults: a developing country perspective
Mubarak M Kazi JI Mohsin R Hashmi A Naqvi SA Ul Hassan Rizvi SA 《Journal of cancer research and clinical oncology》2012,138(2):189-194
Background
There is no data on the histopathological characteristics of renal tumours in young adults in Pakistan. 相似文献19.
Gerhard Sommer Andreas Schriefl Georg Zeindlinger Andreas Katzensteiner Herwig Ainödhofer Amulya Saxena Gerhard A. Holzapfel 《Acta biomaterialia》2013,9(12):9379-9391
Congenital defects of the esophagus are relatively frequent, with 1 out of 2500 babies suffering from such a defect. A new method of treatment by implanting tissue engineered esophagi into newborns is currently being developed and tested using ovine esophagi. For the reconstruction of the biological function of native tissues with engineered esophagi, their cellular structure as well as their mechanical properties must be considered. Since very limited mechanical and structural data for the esophagus are available, the aim of this study was to investigate the multiaxial mechanical behavior of the ovine esophagus and the underlying microstructure. Therefore, uniaxial tensile, biaxial tensile and extension-inflation tests on esophagi were performed. The underlying microstructure was examined in stained histological sections through standard optical microscopy techniques. Moreover, the uniaxial ultimate tensile strength and residual deformations of the tissue were determined. Both the mucosa-submucosa and the muscle layers showed nonlinear and anisotropic mechanical behavior during uniaxial, biaxial and inflation testing. Cyclical inflation of the intact esophageal tube caused marked softening of the passive esophagi in the circumferential direction. The rupture strength of the mucosa-submucosa layer was much higher than that of the muscle layer. Overall, the ovine esophagus showed a heterogeneous and anisotropic behavior with different mechanical properties for the individual layers. The intact and layer-specific multiaxial properties were characterized using a well-known three-dimensional microstructurally based strain-energy function. This novel and complete set of data serves the basis for a better understanding of tissue remodeling in diseased esophagi and can be used to perform computer simulations of surgical interventions or medical-device applications. 相似文献
20.