全文获取类型
收费全文 | 2169篇 |
免费 | 191篇 |
国内免费 | 65篇 |
专业分类
耳鼻咽喉 | 16篇 |
儿科学 | 109篇 |
妇产科学 | 35篇 |
基础医学 | 281篇 |
口腔科学 | 49篇 |
临床医学 | 273篇 |
内科学 | 461篇 |
皮肤病学 | 33篇 |
神经病学 | 167篇 |
特种医学 | 314篇 |
外科学 | 187篇 |
综合类 | 55篇 |
预防医学 | 171篇 |
眼科学 | 28篇 |
药学 | 146篇 |
中国医学 | 1篇 |
肿瘤学 | 99篇 |
出版年
2021年 | 26篇 |
2020年 | 15篇 |
2019年 | 17篇 |
2018年 | 34篇 |
2017年 | 17篇 |
2016年 | 23篇 |
2015年 | 26篇 |
2014年 | 43篇 |
2013年 | 71篇 |
2012年 | 86篇 |
2011年 | 68篇 |
2010年 | 60篇 |
2009年 | 81篇 |
2008年 | 58篇 |
2007年 | 113篇 |
2006年 | 75篇 |
2005年 | 74篇 |
2004年 | 55篇 |
2003年 | 47篇 |
2002年 | 70篇 |
2001年 | 62篇 |
2000年 | 46篇 |
1999年 | 46篇 |
1998年 | 75篇 |
1997年 | 83篇 |
1996年 | 82篇 |
1995年 | 73篇 |
1994年 | 62篇 |
1993年 | 59篇 |
1992年 | 37篇 |
1991年 | 50篇 |
1990年 | 61篇 |
1989年 | 70篇 |
1988年 | 47篇 |
1987年 | 62篇 |
1986年 | 37篇 |
1985年 | 44篇 |
1984年 | 35篇 |
1983年 | 38篇 |
1982年 | 36篇 |
1981年 | 30篇 |
1980年 | 33篇 |
1979年 | 18篇 |
1978年 | 16篇 |
1977年 | 22篇 |
1976年 | 19篇 |
1975年 | 20篇 |
1973年 | 10篇 |
1970年 | 11篇 |
1969年 | 10篇 |
排序方式: 共有2425条查询结果,搜索用时 15 毫秒
61.
Vincent JJ Odekerken Teus van Laar Michiel J Staal Arne Mosch Carel FE Hoffmann Peter CG Nijssen Guus N Beute Jeroen PP van Vugt Mathieu WPM Lenders M Fiorella Contarino Marieke SJ Mink Lo J Bour Pepijn van den Munckhof Ben A Schmand Rob J de Haan P Richard Schuurman Rob MA de Bie 《Lancet neurology》2013,12(1):37-44
62.
K Guzińska-Ustymowicz J Kiśluk SJ Terlikowski A Pryczynicz K Niewiarowska M Ustymowicz M Hawryluk M Południewski A Kemona 《Advances in medical sciences》2013,58(2):221-226
PurposeWe identify the expression of PRL-3 in primary endometrioid endometrial cancer and metastases in relation to the clinicopathological characteristics.Material/MethodsThe study involved 30 patients with type I endometrial cancer. Twelve of them were diagnosed with metastases in various localization of abdomen. The PRL-3 expression was evaluated on the basis of immunohistochemistry results by the use of monoclonal antibody anti-PRL3 clone 3B6.ResultsThe intensity of PRL-3 expression in correlation with tumor stage was statistically significant (p = 0.024). The strongest reaction was noted in cases classified as a 1a and 1b stage defined by FIGO. The strength of PRL-3 expression is significantly associated with the degree of histological tumor grade (p = 0.035).ConclusionsThe strong expression of PRL-3 in the primary tumor that was significantly correlated with the grade and clinical stage suggest that PTP4A3 participates in the process of endometrial carcinogenesis. 相似文献
63.
64.
65.
Jana Le Diana S. Dorstyn Elias Mpofu Elise Prior Phillip J. Tully 《Quality of life research》2018,27(10):2505-2505
66.
67.
S. Shinde S. M. Yentis K. Asanati R. H. Coetzee A. Cole-King C. Gerada K. Harding K. Hawton A. Hennessy P. Keats N. Kumar A. McGlennan K. Pappenheim E. Plunkett K. Prior A. Rowland 《Anaesthesia》2020,75(1):96-108
Anaesthetists are thought to be at increased risk of suicide amongst the medical profession. The aims of the following guidelines are: increase awareness of suicide and associated vulnerabilities, risk factors and precipitants; to emphasise safe ways to respond to individuals in distress, both for them and for colleagues working alongside them; and to support individuals, departments and organisations in coping with a suicide. 相似文献
68.
SJ Smith CV Rahman PA Clarke AA Ritchie TW Gould JH Ward KM Shakesheff RG Grundy R Rahman 《Annals of the Royal College of Surgeons of England》2014,96(7):495-501
Introduction
The median survival of patients with glioblastoma multiforme (astrocytoma grade 4) remains less than 18 months despite radical surgery, radiotherapy and systemic chemotherapy. Surgical implantation of chemotherapy eluting wafers into the resection cavity has been shown to improve length of survival but the current licensed therapy has several drawbacks. This paper investigates in vivo efficacy of a novel drug eluting paste in glioblastoma.Methods
Poly(lactic-co-glycolic acid)/poly(ethylene glycol) (PLGA/PEG) self-sintering paste was loaded with the chemotherapeutic agent etoposide and delivered surgically into partially resected tumours in a flank murine glioblastoma xenograft model.Results
Surgical delivery of the paste was successful and practical, with no toxicity or surgical morbidity to the animals. The paste was retained in the tumour cavity, and preliminary results suggest a useful antitumour and antiangiogenic effect, particularly at higher doses. Bioluminescent imaging was not affected significantly by the presence of the paste in the tumour.Conclusions
Chemotherapy loaded PLGA/PEG paste seems to be a promising technology capable of delivering active drugs into partially resected tumours. The preliminary results of this study suggest efficacy with no toxicity and will lead to larger scale efficacy studies in orthotopic glioblastoma models. 相似文献69.
巨噬细胞迁移抑制因子最初是由于能抑制体外巨噬细胞随机迁移而被发现,现在它作为一种重要的调节因子参与一系列炎症性疾病过程.我们最近发现,巨噬细胞迁移抑制因子的缺失使一些由炎症介质诱发的白细胞-内皮细胞相互作用减弱,提示巨噬细胞迁移抑制因子在炎症反应中起作用的机制之一是促进白细胞聚集.…… 相似文献
70.