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排序方式: 共有10000条查询结果,搜索用时 15 毫秒
991.
Xiaoxia Zhou MD Zhenhua Liu MD PhD Xiaoting Zhou MD Yaqin Xiang MD Zhou Zhou MD Yuwen Zhao MD Hongxu Pan MD Qian Xu MD PhD Yase Chen MD PhD Qiying Sun MD PhD Xinyin Wu PhD Hongzhuan Tan PhD Bin Li PhD Kai Yuan PhD Yali Xie MD Weihua Liao MD PhD Shuo Hu PhD Jianping Zhu BS Xuehong Wu PhD Jianhua Li MS Chunyu Wang MD PhD Lifang Lei MD PhD Jiayu Tang MD Yonghong Liu MD Heng Wu MD Wei Huang MD Tao Wang MD Zheng Xue MD Puqing Wang MD Zhentao Zhang MD PhD Ping Xu MD Ling Chen MD Qing Wang MD PhD Xuejing Wang MD PhD Oumei Cheng MD Yuefei Shen MD Weiguo Liu MD Min Ye MD Yong You MD PhD Jinchen Li PhD Xinxiang Yan MD Jifeng Guo MD PhD Beisha Tang MD for Parkinson's Disease & Movement Disorders Multicenter Database Collaborative Network in China 《Movement disorders》2022,37(7):1335-1345
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Emily Behling MD Candidate Luis C. Farhat MD Angeli Landeros-Weisenberger MD Michael H. Bloch MD MS 《Movement disorders》2022,37(4):684-693
Vesicular monoamine transporter type 2 (VMAT2) inhibitors may be an effective therapy for chronic tic disorders (CTD), including Tourette syndrome (TS), but there has not been a meta-analysis compiling available evidence from randomized controlled trials (RCTs). We performed a systematic review and meta-analysis to evaluate the efficacy, acceptability, and tolerability of VMAT2 inhibitors for CTD/TS. PubMed, CENTRAL, and Embase were searched for double-blinded RCTs of VMAT2 inhibitors versus placebo for the treatment of CTD/TS. Change in tic severity measured by the Yale Global Tic Severity Scale (efficacy) and rates of discontinuation attributed to adverse effects (tolerability) or all causes (acceptability) were extracted closest to 12 weeks. Mean difference (MD) and odds ratio (OR) were the effect size indexes for efficacy and acceptability/tolerability, respectively. Data were pooled through random-effects meta-analysis weighted by inverse variance. Five RCTs involving eight comparisons were included. Meta-analysis found a nonsignificant effect on efficacy (k = 8; N = 583; MD = −0.71; 95% confidence interval [CI], −1.93 to 0.50; P = 0.24), and there was certainty that the true effect is nonclinically meaningful (high quality of evidence). Meta-analysis found decreased tolerability (k = 7; N = 626; OR = 2.67; 95% CI, 1.21–5.92; P = 0.01) and decreased acceptability (k = 8; N = 626; OR = 1.90; 95% CI, 1.14–3.18; P = 0.01), although those comparisons were limited because of the relatively small number of events across trials. Meta-analyses did not support the efficacy of VMAT2 inhibitors in the short-term treatment of tic disorders and suggested no clinically meaningful effect of these agents on tic symptoms. © 2022 International Parkinson and Movement Disorder Society 相似文献
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Rosalie M. Grijalva BS Nha Trang Thu Pham BS Qiao Huang PhD Peter R. Martin MS Farwa Ali MD Heather M. Clark PhD Joseph R. Duffy PhD Rene L. Utianski PhD Hugo Botha MD Mary M. Machulda PhD Stephen D. Weigand MS J. Eric Ahlskog PhD MD Dennis W. Dickson MD Keith A. Josephs MD MST MSc Jennifer L. Whitwell PhD 《Movement disorders》2022,37(4):702-712
996.
Biallelic AOPEP Loss-of-Function Variants Cause Progressive Dystonia with Prominent Limb Involvement
Michael Zech MD Kishore R. Kumar MBBS PhD FRACP Sophie Reining MD Janine Reunert PhD Michel Tchan MBBS PhD FRACP Lisa G. Riley PhD Alexander P. Drew PhD Robert J. Adam MA MBBS PhD FRACP FRCP Riccardo Berutti PhD Saskia Biskup MD Nicolas Derive PhD Somayeh Bakhtiari PhD Sheng Chih Jin PhD Michael C. Kruer MD Tanya Bardakjian MS Pedro Gonzalez-Alegre MD PhD Ignacio J. Keller Sarmiento MD Niccolo E. Mencacci MD PhD Steven J. Lubbe PhD Manju A. Kurian PhD Fabienne Clot PhD Aurélie Méneret MD PhD Jean-Madeleine de Sainte Agathe MD Victor S.C. Fung MBBS PhD FRACP Marie Vidailhet MD Matthias Baumann MD Thorsten Marquardt MD Juliane Winkelmann MD Sylvia Boesch MD 《Movement disorders》2022,37(1):137-147
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998.
4D flow MRI can detect subtle right ventricular dysfunction in primary left ventricular disease
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999.
Diffusion‐weighted imaging using readout‐segmented echo‐planar imaging,parallel imaging,and two‐dimensional navigator‐based reacquisition in detecting acute optic neuritis
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1000.
Reproducibility and interobserver variability of systolic blood flow velocity and 3D wall shear stress derived from 4D flow MRI in the healthy aorta
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