全文获取类型
收费全文 | 8373篇 |
免费 | 567篇 |
国内免费 | 52篇 |
专业分类
耳鼻咽喉 | 43篇 |
儿科学 | 223篇 |
妇产科学 | 249篇 |
基础医学 | 1379篇 |
口腔科学 | 182篇 |
临床医学 | 901篇 |
内科学 | 1666篇 |
皮肤病学 | 181篇 |
神经病学 | 839篇 |
特种医学 | 291篇 |
外国民族医学 | 7篇 |
外科学 | 736篇 |
综合类 | 42篇 |
一般理论 | 2篇 |
预防医学 | 704篇 |
眼科学 | 86篇 |
药学 | 658篇 |
中国医学 | 19篇 |
肿瘤学 | 784篇 |
出版年
2024年 | 11篇 |
2023年 | 64篇 |
2022年 | 113篇 |
2021年 | 216篇 |
2020年 | 153篇 |
2019年 | 203篇 |
2018年 | 210篇 |
2017年 | 171篇 |
2016年 | 237篇 |
2015年 | 243篇 |
2014年 | 349篇 |
2013年 | 415篇 |
2012年 | 674篇 |
2011年 | 799篇 |
2010年 | 420篇 |
2009年 | 378篇 |
2008年 | 605篇 |
2007年 | 650篇 |
2006年 | 606篇 |
2005年 | 578篇 |
2004年 | 493篇 |
2003年 | 401篇 |
2002年 | 388篇 |
2001年 | 52篇 |
2000年 | 43篇 |
1999年 | 64篇 |
1998年 | 77篇 |
1997年 | 79篇 |
1996年 | 62篇 |
1995年 | 43篇 |
1994年 | 43篇 |
1993年 | 31篇 |
1992年 | 29篇 |
1991年 | 11篇 |
1990年 | 7篇 |
1989年 | 6篇 |
1988年 | 5篇 |
1987年 | 4篇 |
1986年 | 8篇 |
1985年 | 7篇 |
1984年 | 6篇 |
1983年 | 8篇 |
1982年 | 4篇 |
1981年 | 3篇 |
1980年 | 4篇 |
1979年 | 3篇 |
1977年 | 2篇 |
1973年 | 2篇 |
1970年 | 4篇 |
1968年 | 2篇 |
排序方式: 共有8992条查询结果,搜索用时 0 毫秒
91.
Stanislava Erdelja Petra Vokal Marija Bolfan Sergej Augustin Erdelja Branka Begovac Ivan Begovac 《Croatian medical journal》2013,54(5):460-468
Aim
To assess the relationships between delinquency and demographic and family variables, academic performance, war stressors, home/community, school, and media violence exposure, self-image, and psychopathology.Methods
This cross-sectional study included 100 delinquent, incarcerated male adolescents and 100 matched schoolchildren from Croatia. It lasted from January 2008 to June 2009, and used socio-demographic questionnaire, questionnaire on children’s stressful and traumatic war experiences, exposure to violence scale, the Offer Self-Image Questionnaire, and Youth Self-Report Questionnaire.Results
Logistic regression analysis showed that delinquency in incarcerated adolescents was more likely related to having parents who did not live together (odds ratio [OR] 2.40; confidence interval [CI] 1.18-4.90, P = 0.015), being more exposed to violence at home/community (OR 3.84; CI 1.58-9.34, P = 0.003), and having poorer self-image (OR 1.09; CI = 1.03-1.16, P < 0.002).Conclusion
Preventive and therapeutic interventions in incarcerated delinquents should be specifically targeted toward single parenthood, family factors, trauma oriented interventions, and focused on multiple dimensions of self-concept of adolescents.Delinquency is associated with many risk factors, including demographic, genetic, and family characteristics (single parenthood) or academic performance. Many studies have focused on exposure to various forms of violence – in the family or home; community and neighborhood; in school and peer groups; and the media, but other risk factors have also found to be important, such as poorer self-image, various forms of psychopathology, and social characteristics (neighborhoods characterized by poverty) (1-15). Most of the studies dealing with delinquency aim to develop therapeutic interventions in relation to the obtained factors or mediators (9,11,16).There are relatively few studies on incarcerated adolescents. Many report on delinquents’ traumatic experiences, posttraumatic stress disorder, and importance of developmental tasks of adolescence and parental monitoring (14,17,18). Therapeutic interventions are specifically directed toward assessment and intervention of trauma and psychopathology, and family interventions are used very often.There are not many studies on delinquents in Croatia and most of them deal with a model that takes into account the interplay between protective and risk factors (19-21). Factors that are often mentioned are parental distrust and punishment, and family dysfunctionality (22-24). The prevalence of delinquency in the last few years has not been reducing (25), which suggests that the current preventive and therapeutic efforts have not been sufficient (25). Another important factor that has to be considered when studying delinquency in Croatia is the influence of Croatian War for Independence 1991-1995. The relationship between war experiences (direct or indirect) and the development of delinquency in adolescents has been relatively rarely described, with contradictory findings. Some studies found no association between the impact of war and bullying (26), whereas others found a relationship between aggressiveness in child refugees and their past war experiences (27) or experiences of their parents, war veterans (28). Besides war-related violence, we expected that delinquency was related to the exposure to other types of violence, eg, violence at home (29). Finally, we also expected an association with poorer self-image (8) and the presence of significant psychopathological syndromes (7).Our aim was therefore to examine the relationship between demographic, family factors, academic performance, exposure to violence in different contexts (home, community, school, media, war related stress), psychopathology, and delinquency. 相似文献92.
93.
Koop Barbara Elisabeth Mayer Felix Gündüz Tanju Blum Jacqueline Becker Julia Schaffrath Judith Wagner Wolfgang Han Yang Boehme Petra Ritz-Timme Stefanie 《International journal of legal medicine》2021,135(1):167-173
International Journal of Legal Medicine - Age estimation based on the analysis of DNA methylation patterns has become a focus of forensic research within the past few years. However, there is... 相似文献
94.
95.
96.
Isabel Fragata Teresa Morais Rita Silva Ana Paiva Nunes Petra Loureiro Jos Diogo Martins Jaime Pamplona Rui Carvalho Mariana Baptista Joo Reis 《Interventional neuroradiology》2021,27(1):16
IntroductionMechanical thrombectomy is standard treatment for large vessel occlusion (LVO) in adults. There are no randomized controlled trials for the pediatric population. We report our single-center experience with thrombectomy of LVO in a series of pediatric patients, and perform a review of the literature.MethodsRetrospective review of consecutive pediatric thrombectomy cases between 2011 and 2018. Demographic variables, imaging data, technical aspects and clinical outcome were recorded.ResultsIn a period of 7 years, 7 children were treated for LVO at our center. Median age was 13 (2–17), and median Ped-NIHSS was 15 (3–24), and the median ASPECTS was 8 (2–10). Five patients had cardiac disease, and 2 of them were under external cardiac assistance. Median time from onset of symptoms to beginning of treatment was 7h06m (2h58m–21h38m). Five patients had middle cerebral artery occlusions. Thrombectomy was performed using a stentriever in 3 patients, aspiration in 3 patients, and combined technique in 1 patient. Six patients had good recanalization (TICI 2 b/3). There were no immediate periprocedural complications. At 3 months, 4 patients (57%) were independent (mRS score <3). Two patients died, one after haemorrhagic transformation of an extensive MCA infarct, and one due to extensive brainstem ischemia in the setting of varicella vasculitis.DiscussionSelected pediatric patients with LVO may be treated with mechanical thrombectomy safely. In patients under external cardiac assistance and under anticoagulation, thrombectomy is the only alternative for treatment of LVO. A multidisciplinary approach in specialized pediatric stroke centers with trained neurointerventionalists are essential for good results. 相似文献
97.
Silke Keller Anke Liedek Dalia Shendi Monika Bach Günter E. M. Tovar Petra J. Kluger Alexander Southan 《RSC advances》2020,10(58):35273
Azide-bearing cell-derived extracellular matrices (“clickECMs”) have emerged as a highly exciting new class of biomaterials. They conserve substantial characteristics of the natural extracellular matrix (ECM) and offer simultaneously small abiotic functional groups that enable bioorthogonal bioconjugation reactions. Despite their attractiveness, investigation of their biomolecular composition is very challenging due to the insoluble and highly complex nature of cell-derived matrices (CDMs). Yet, thorough qualitative and quantitative analysis of the overall material composition, organisation, localisation, and distribution of typical ECM-specific biomolecules is essential for consistent advancement of CDMs and the understanding of the prospective functions of the developed biomaterial. In this study, we evaluated frequently used methods for the analysis of complex CDMs. Sodium dodecyl sulphate polyacrylamide gel electrophoresis (SDS-PAGE) and (immune)histochemical staining methods in combination with several microscopic techniques were found to be highly eligible. Commercially available colorimetric protein assays turned out to deliver inaccurate information on CDMs. In contrast, we determined the nitrogen content of CDMs by elementary analysis and converted it into total protein content using conversion factors which were calculated from matching amino acid compositions. The amount of insoluble collagens was assessed based on the hydroxyproline content. The Sircol™ assay was identified as a suitable method to quantify soluble collagens while the Blyscan™ assay was found to be well-suited for the quantification of sulphated glycosaminoglycans (sGAGs). Eventually, we propose a series of suitable methods to reliably characterise the biomolecular composition of fibroblast-derived clickECM.Common characterisation methods for cell-derived extracellular matrices (ECMs) are compared using both unmodified and azide-bearing fibroblast-derived ECM. 相似文献
98.
99.