全文获取类型
收费全文 | 12541篇 |
免费 | 889篇 |
国内免费 | 66篇 |
专业分类
耳鼻咽喉 | 84篇 |
儿科学 | 328篇 |
妇产科学 | 362篇 |
基础医学 | 1863篇 |
口腔科学 | 245篇 |
临床医学 | 1352篇 |
内科学 | 2890篇 |
皮肤病学 | 269篇 |
神经病学 | 1175篇 |
特种医学 | 439篇 |
外国民族医学 | 7篇 |
外科学 | 1398篇 |
综合类 | 79篇 |
一般理论 | 2篇 |
预防医学 | 895篇 |
眼科学 | 139篇 |
药学 | 987篇 |
中国医学 | 21篇 |
肿瘤学 | 961篇 |
出版年
2023年 | 79篇 |
2022年 | 120篇 |
2021年 | 279篇 |
2020年 | 195篇 |
2019年 | 261篇 |
2018年 | 284篇 |
2017年 | 230篇 |
2016年 | 312篇 |
2015年 | 328篇 |
2014年 | 465篇 |
2013年 | 552篇 |
2012年 | 868篇 |
2011年 | 1022篇 |
2010年 | 536篇 |
2009年 | 485篇 |
2008年 | 792篇 |
2007年 | 885篇 |
2006年 | 789篇 |
2005年 | 783篇 |
2004年 | 683篇 |
2003年 | 588篇 |
2002年 | 575篇 |
2001年 | 213篇 |
2000年 | 195篇 |
1999年 | 188篇 |
1998年 | 134篇 |
1997年 | 127篇 |
1996年 | 100篇 |
1995年 | 74篇 |
1994年 | 71篇 |
1993年 | 58篇 |
1992年 | 119篇 |
1991年 | 72篇 |
1990年 | 66篇 |
1989年 | 89篇 |
1988年 | 63篇 |
1987年 | 80篇 |
1986年 | 70篇 |
1985年 | 60篇 |
1984年 | 54篇 |
1983年 | 46篇 |
1982年 | 39篇 |
1981年 | 30篇 |
1979年 | 30篇 |
1977年 | 28篇 |
1976年 | 28篇 |
1975年 | 30篇 |
1974年 | 38篇 |
1973年 | 23篇 |
1971年 | 27篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
31.
Free amino acid concentrations of CSF were measured in bacterial meningitis, aseptic meningitis, meningoradiculitis Garin-Bujadoux-Bannwarth, multiple sclerosis, carcinomatous meningitis, and controls. Almost all CSF amino acids were highly elevated in bacterial but not in aseptic meningitis, meningoradiculitis Garin-Bujadoux-Bannwarth or carcinomatous meningitis thus providing a laboratory tool for their differential diagnosis. In carcinomatous meningitis the amino acid pattern indicates metabolic activity of tumor cells. Minimal alterations were found in multiple sclerosis which have no diagnostic value. 相似文献
32.
J Schneider M Meier D Maroske H Kaffarnik 《Clinica chimica acta; international journal of clinical chemistry》1988,171(2-3):305-310
In spite of significant advances in the past decade, assessing of severe prognosis in acute pancreatitis remains an improvable problem. Actually the standardized means are clinical, multiple laboratory and peritoneal lavage. In a series of 20 subsequent cases of acute pancreatitis with a lethality of 30%, apolipoprotein AII has proven to be a predictor of fatal outcome with a sensitivity in the range of all other methods together. Competitive replacement of Apo AII by serum amyloid like substance A as an indicator for the amount of necrosis would explain this relation. Whether this suggestion can be confirmed by ongoing work or not, apolipoprotein AII merits attention in this context. 相似文献
33.
Petra Thurmüller Maria Troulis Mary Jane O'Neill Leonard B Kaban 《Journal of oral and maxillofacial surgery》2002,60(9):1038-1044
PURPOSE: A standardized, noninvasive technique to assess healing of the mandibular distraction wound is not available. Current methods include clinical examination, plain radiography, and computed tomography. These imaging techniques are expensive and obligate the patient to serial radiation exposure. In addition, anatomic overlap and metal artifacts may obscure the distraction gap. In contrast, ultrasound has been shown to be a noninvasive, efficient, and inexpensive way to evaluate bone healing. The purpose of this study was to test the feasibility of ultrasound to evaluate an experimental mandibular distraction osteogenesis wound. MATERIALS AND METHODS: Distraction devices were placed via a submandibular incision into 24 minipigs. The protocol consisted of 0-day latency and distraction rates of 1, 2, or 4 mm/d for a 12-mm gap. The wounds were assessed in vivo after 0, 8, 16, and 24 days of neutral fixation. Ex vivo radiographs were used to estimate bone fill using a semiquantitative score. A semiquantitative ultrasound score was assigned, and the beam penetration depth was measured in millimeters. RESULTS: In all groups, clinical stability of the distraction wound increased with the duration of fixation. Plain radiographs, taken during neutral fixation, showed that the desired distraction gap was achieved and maintained. The ultrasound score increased with fixation time, whereas beam penetration depth decreased as expected. Ex vivo radiographs showed increasing bone fill score with time and paralleled the ultrasound score. CONCLUSIONS: The results of this feasibility study indicate that ultrasound is potentially useful for the assessment of bone formation in distraction osteogenesis wounds. 相似文献
34.
35.
Petra J. Jeffery Samuel Sostre L R. Scherer Wayne Kasecamp Edwaldo E. Camargo 《European journal of nuclear medicine and molecular imaging》1990,17(6-8):365-368
We report a case of massive cerebrospinal fluid (CSF) leakage where the tracer injected intra-thecally for radionuclide cisternography was later visualized in the bowel as well as the nasopharynx. We discuss the potential implications of this finding in patients with CSF leaks. A brief review of the diagnosis of CSF leaks is included. 相似文献
36.
Emad Dean Nukta Bernhard Meier Philip Urban Thierry Muller Pierre A. Dorsaz Josiane Favre 《Catheterization and cardiovascular interventions》1992,25(4):272-277
The Magnum system, initially designed for coronary angioplasty (PTCA) of chronic total occlusion, consists of a balloon catheter and a solid steel 0.021 inch (0.53 mm) steerable and removable wire with a soft and moldable distal portion, tipped with a 1 mm olive. To evaluate its performance in routine PTCA, 200 unselected consecutive patients were randomized to two equal groups, i.e., group Magnum (100 patients, 115 vessels) and group Standard (100 patients, 118 vessels) including 18 and 21 patients with chronic total occlusions, respectively. Randomization was performed by the sealed envelope system in the catheterization laboratory and crossover of system was imposed if it was not possible to place a balloon correctly within 20 min of fluoroscopy time. There were no significant differences between groups concerning clinical and angiographic baseline characteristics, size of initial balloons (3.0±0.3 mm in both groups), fluoroscopy time to cross the lesion with the wire (Magnum: 4±5, Standard: 5±6 min), total fluoroscopy time (Magnum: 11 ± 9, Standard: 12±12 min), and need for crossover (Magnum: 10%, Standard: 16%). Success rates per lesion were comparable with 90% in group Magnum and 84% in group Standard, as were the complications with one inhospital death in group Standard, occurring three weeks after PTCA and stent implantation. There was no emergency operation. Six patients per group had myocardial infarction of whom two in group Magnum and one in group Standard developed a Q-wave. The following variables were significantly in favor of the Magnum system compared with the Standard system: success rate in nontotal lesions (97% versus 90%) crossover success in total occlusions (0 vs. 33%), fluoroscopy time to cross the lesion with the balloon once the wire was in place (1 ± 2 vs. 2 ± 4 min), and use of a single versus 1.2±0.5 wires per lesion. The only advantage of the Standard systems was the more common use of 7 French guiding catheters (Magnum: 40%, Standard: 53%, p = 0.09). The Magnum system compares favorably with standard systems for routine PTCA. The robust design of the Magnum wire does not impair ease of placement and safety but saves material and facilitates balloon advancement across the lesion. 相似文献
37.
Ralf-Peter Vonberg Sabine Stamm-Balderjahn Sonja Hansen Irina Zuschneid Henning Ruden Michael Behnke Petra Gastmeier 《Infection control and hospital epidemiology》2006,27(10):1123-1127
A systematic search was performed to identify outbreaks of methicillin-resistant Staphylococcus aureus infection and colonization caused by healthcare workers (HCWs). Of 191 outbreaks identified, 11 had strong epidemiological evidence that HCWs were the source. In 3 of these outbreaks, asymptomatic carriers were the cause. The frequent practice of screening asymptomatic HCWs should be reconsidered. 相似文献
38.
The traumatic dural sinus injury — a clinical study 总被引:5,自引:0,他引:5
Summary In a period of 13 years 978 cases of severe head injuries were operated on in our clinic. An analysis of the medical reports includes injuries of the superficial dural sinus (39 cases=4%): among these injuries of the anterior and central part of the superior sagittal sinus (66 per cent), injuries of the transverse sinus (18 per cent), injuries of the posterior part of the superior sagittal sinus (8 per cent), and combined injuries of different dural sinuses (8 per cent).Clinical data, i.e. the causes of accident, radiological examination results, intracranial lesions, operation technqiues and outcome are analysed and discussed. The analysis of cases with dural sinus injuries shows a high mortality rate (total mortality rate: 16 patients=41%; intra-operative mortality rate: 8 patients=20%). 相似文献
39.
40.
J J Meier S Deifuss A Klamann W Schmiegel M A Nauck 《Experimental and clinical endocrinology & diabetes》2003,111(6):344-350
INTRODUCTION: Patients with type 2 diabetes show a significantly higher mortality after acute myocardial infarction than non-diabetic patients. The influence of sulfonylureas on the survival after acute myocardial infarction is still under debate. PATIENTS AND METHODS: Survival of 562 patients, consecutively admitted to an intensive care unit with the diagnosis acute myocardial infarction, was prospectively assessed for > 3 years. At the time of hospital admission, patients were grouped as (a) non-diabetic patients; (b) patients with newly diagnosed type 2 diabetes; (c) patients with known type 2 diabetes not treated with sulfonylureas and (d) patients with known type 2 diabetes treated with sulfonylureas. Survival-analysis was performed according to Kaplan-Meier. RESULTS: 324 patients were non-diabetics, in 86 cases type 2 diabetes was newly diagnosed at the time of hospital admission, 77 patients with known diabetes had taken sulfonylureas (glibenclamide in all cases) prior to the acute myocardial infarction, 75 patients were on any other antidiabetic treatment. Long-term-survival was significantly shorter in patients with type 2 diabetes compared to the non-diabetic patients (p < 0.0001). However, no significant differences were observed between the patients with type 2 diabetes treated with sulfonylurea-drugs and those receiving any other antidiabetic treatment (p = 0.53) CONCLUSIONS: An antidiabetic treatment with sulfonylurea-drugs prior to acute myocardial infarction does not have negative effects on the long-term survival. Larger prospective studies will be necessary to finally clarify this question. 相似文献