全文获取类型
收费全文 | 373篇 |
免费 | 17篇 |
国内免费 | 1篇 |
专业分类
耳鼻咽喉 | 1篇 |
儿科学 | 5篇 |
妇产科学 | 4篇 |
基础医学 | 26篇 |
口腔科学 | 34篇 |
临床医学 | 24篇 |
内科学 | 127篇 |
皮肤病学 | 4篇 |
神经病学 | 6篇 |
特种医学 | 7篇 |
外科学 | 68篇 |
预防医学 | 6篇 |
眼科学 | 42篇 |
药学 | 11篇 |
肿瘤学 | 26篇 |
出版年
2023年 | 4篇 |
2022年 | 5篇 |
2021年 | 6篇 |
2020年 | 8篇 |
2019年 | 12篇 |
2018年 | 18篇 |
2017年 | 5篇 |
2016年 | 12篇 |
2015年 | 10篇 |
2014年 | 13篇 |
2013年 | 17篇 |
2012年 | 28篇 |
2011年 | 26篇 |
2010年 | 20篇 |
2009年 | 13篇 |
2008年 | 24篇 |
2007年 | 24篇 |
2006年 | 19篇 |
2005年 | 18篇 |
2004年 | 29篇 |
2003年 | 28篇 |
2002年 | 22篇 |
2001年 | 8篇 |
2000年 | 7篇 |
1999年 | 5篇 |
1998年 | 2篇 |
1997年 | 1篇 |
1996年 | 1篇 |
1995年 | 1篇 |
1993年 | 1篇 |
1991年 | 2篇 |
1987年 | 1篇 |
1985年 | 1篇 |
排序方式: 共有391条查询结果,搜索用时 15 毫秒
81.
Sorkou Konstantina N. Manthou Maria-Eleni Tsaousis Konstantinos T. Brazitikos Periklis Tsinopoulos Ioannis T. 《Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie》2018,256(9):1631-1637
Graefe's Archive for Clinical and Experimental Ophthalmology - In the present study, we aimed to examine the anterior lens capsule using transmission electron microscopy (TEM) and compare the... 相似文献
82.
83.
Usage patterns and 2‐year outcomes with the TAXUS express stent: Results of the US ARRIVE 1 registry
84.
Michael Doulberis Periklis Panagopoulos Stephanie Scherz Erminia Dellaporta 《Scandinavian journal of gastroenterology》2016,51(8):893-902
Ischemic colitis is the result of colonic hypoperfusion and is regarded as a relatively rare condition. It can be roughly classified as occlusive and non-occlusive. Pathogenesis includes a usually transient compromise in the colonic vasculature, with a parallel activation of an inflammatory cascade caused primarily by reperfusion. Diagnosis of ischemic colitis remains often difficult and requires a combination of diagnostic techniques, whereas clinical signs are occasionally only seen late as complications. Gold standard is considered to be colonoscopy. Clinical presentation and treatment of ischemic colitis vary widely depending on the degree of ischemia. Patients of intensive care unit (ICU) with ischemic colitis are often under-diagnosed, since the parallel co-morbidities and the nonspecific nature of symptoms that mimic almost any abdominal pathology, can mislead the doctor. Moreover, sedated or ventilated patients can mask many of the characteristic features of ischemic colitis and make the diagnosis challenging. Bedside colonoscopy and diagnostic laparoscopy in ICUs are two options, which seem lately to be reliable and promising in diagnosing ischemic colitis in critically ill patients. 相似文献
85.
Identification of an erm(A) erythromycin resistance methylase gene in Streptococcus pneumoniae isolated in Greece 总被引:8,自引:0,他引:8
Syrogiannopoulos GA Grivea IN Tait-Kamradt A Katopodis GD Beratis NG Sutcliffe J Appelbaum PC Davies TA 《Antimicrobial agents and chemotherapy》2001,45(1):342-344
In a serotype 11A clone of erythromycin-resistant pneumococci isolated from young Greek carriers, we identified the nucleotide sequence of erm(A), a methylase gene previously described as erm(TR) in Streptococcus pyogenes. The erm(A) pneumococci were resistant to 14- and 15-member macrolides, inducibly resistant to clindamycin, and susceptible to streptogramin B. To our knowledge, this is the first identification of resistance to erythromycin in S. pneumoniae attributed solely to the carriage of the erm(A) gene. 相似文献
86.
87.
Pappas KD Gouva CD Katopodis KP Nikolopoulos PM Korantzopoulos PG Michalis LK Goudevenos JA Siamopoulos KC 《Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy》2008,22(1):37-44
Background It is not clear whether the correction of anemia with erythropoietin (rhuEpo) in patients with chronic kidney disease (CKD)
has any benefit on cardiac function and geometry. Most studies are based on indices of systolic function and left ventricular
mass (LVM) and the results are conflicting.
Patients and methods We sought to investigate the effect of rhuEpo on LV systolic and diastolic performance using conventional and novel echocardiographic
indices. Thirty one patients with CKD (stage 3 or 4) were included. Fifteen patients (group I) treated with rhuEpo targeting
at Hb ≥13.0 g/dL, while the remaining (group II) were not treated. Clinical and laboratory parameters were recorded at baseline
and 1 year later. Ejection fraction (EF) and LVM were carefully determined. Diastolic function was assessed by mitral inflow
indices (E and A wave velocities, Edt deceleration time and E/A) and novel indices of mitral annulus motion using Tissue Doppler
Imaging (Em, Am, and E/Em). An index of global cardiac function (Tei) was also calculated.
Results At baseline, the 2 groups had comparable clinical and laboratory characteristics. After 1 year, a significant improvement
in Hb levels (13.6 ± 1.2 vs 10.3 ± 1.2 g/dL, p < 0.05) as well as in systolic and diastolic function indexes was observed in group I compared to group II patients: EF (70.5 ± 7.6
vs 63.4 ± 9.3%, p < 0.05), LVM (116.5 ± 34.9 vs 155.6 ± 51.6 g/m2, p < 0.05), Edt (233.9 ± 98.6 vs 166.9 ± 45.1 ms, p < 0.05), Tei index (0.35 ± 0.12 vs 0.51 ± 0.17, p < 0.01) and E/Em (9.7 ± 2.4 vs 14.8 ± 5.2, p < 0.05), respectively. Blood pressure and heart rate did not show significant changes.
Conclusions Correction of anemia with rhuEpo in patients with CKD seems to improve cardiac performance and geometry. 相似文献
88.
The technique described offers a digital workflow for designing and fabricating a combination cement- and screw-retained implant-supported prosthesis. After making the definitive impression and definitive stone cast, the definitive combination prosthesis is digitally designed. Custom-milled titanium abutments and cementable superstructure prosthesis are designed and milled by having occlusal access channels of the prosthesis correspond to the occlusal access channels of the custom abutments. After intraorally confirming the esthetics, occlusion, and fit, the prosthesis is cemented intraorally and removed as a screw-retained prosthesis. After excess cement is removed, the combination prosthesis is placed intraorally, and composite resin is used to seal the occlusal access channels. 相似文献
89.
90.