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101.
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Borkowska A Leszczyńska-Rodziewicz A Kapelski P Hauser J Janusz R 《Psychiatria polska》2005,39(3):481-495
THE AIM AND METHODS: The aim of this study was to assess the intensity and frequency of eye movement abnormalities measured with infrared reflectometry, and working memory disturbances assessed with the Wisconsin Card Sorting Test (WCST). The study was performed in 87 patients with bipolar affective illness, in 119 patients with schizophrenia and in 90 healthy persons. In patients, the assessment was done during a mild symptomatic period or in remission. RESULTS: In patients with bipolar affective illness significant disturbances of eye movement and working memory compared with healthy subjects were found. Frequency and intensity of fixation abnormalities was less intense compared to schizophrenic patients, while smooth pursuit abnormalities had a similar degree. Working memory disturbances in bipolar patients were, as to the ability of formulation of logical conception, of similar degree as in schizophrenia. On the other hand, as to the effectiveness of thinking, no difference compared with healthy controls was found. CONCLUSIONS: The results obtained suggest that eye movement and working memory disturbances may constitute neurophysiological and neuropsychological endophenotypic markers of bipolar affective illness what makes possible using them in molecular genetic studies of this illness. 相似文献
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Januchowski R Breborowicz AK Ofori H Jedrzejczak P Pawelczyk L Jagodzinski PP 《Journal of andrology》2004,25(5):757-760
105.
Evaluation of the possibility to assess bone age on the basis of DXA derived hand scans—preliminary results 总被引:2,自引:0,他引:2
Pawe??P?udowski Micha??Lebiedowski Roman?S.?LorencEmail author 《Osteoporosis international》2004,15(4):317-322
The classical method of skeletal age assessment is based on the recognition of changes in the radiographic appearance of the maturity indicators in hand-wrist radiographs by comparison with a reference atlas. The purpose of this study was the evaluation of the possibility to assess bone age using a less invasive method such as dual-energy X-ray absorptiometry (DXA). Bone ages of 50 children free of any chronic diseases (5–18 years old) and ten with multihormonal pituitary deficiency (MPD) (8–20 years old) were assessed using an Expert-XL densitometer. Hand scans and classical hand-wrist radiographs were evaluated by two independent observers for bone age by visual comparison with reference standards of skeletal development published in the atlas. The precision errors of duplicate bone age ratings were low both for radiographs (<1%) and DXA hand scans (<0.9%). A high degree of agreement between bone age ratings done by two observers was assessed by intraclass correlation coefficients. The same bone age based on radiographs and DXA hand scans was assessed in 44 of 60 cases (73.3%); in 16 cases the differences between bone age were no higher than 0.5 year. No significant difference between mean bone age based on radiographs and DXA hand scans was observed (P>0.05). Moreover, there was a very strong correlation between bone age results (r=0.998; r
2=0.996; P<0.0001), indicating agreement of bone age assessments based on DXA and radiographic images. Remarkable differences (up to 3 years) between bone age and chronological age were observed in healthy subjects, probably reflecting the effect of the secular trend towards earlier maturation or alterations in pubertal development. The study indicates that evaluation of skeletal maturity using DXA images is less invasive (up to 8 µSv) than radiography, giving results comparable to the classical method. 相似文献
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Strek P Zagólski O Swierczyńska M Nizankowska E Szałapata-Kraśniak M 《Otolaryngologia polska. The Polish otolaryngology》2004,58(3):451-457
Surgical treatment of bilateral vocal fold paralysis must be undertaken if such a condition lasts 6-12 months or longer and causes dyspnoea. The purpose of the procedures is to assure proper airflow through the glottis and to preserve good voice and unimpaired swallowing. Modern endoscopic surgery of the glottis is performed with CO2 laser. The following paper presents results of laser posterior cordotomy performed in 17 patients aged 19-73 years suffering from bilateral vocal fold paralysis. Results and conclusions: In 7 patients the range of vocal fold resection had to be expanded. 3 individuals developed post-operative granulation in subglottal region. Spirometry and electroglottography were performed before and after the operation to assess the patients' laryngeal functions: respiration and voice quality. The results indicate that laser cordectomy was effective in the discussed group of patients. 相似文献
108.
Starek A Struciński P Dobrzańska-Tatarczuch L 《Roczniki Państwowego Zak?adu Higieny》2004,55(3):207-215
The paper briefly reviews available data on occupational exposure to nitrous oxide and health consequences in medical staff. Special attention is paid on causes of nitrous oxide contamination in occupational environment and monitoring its concentrations. On the basis of the epidemiological studies it was ascertained that nitrous oxide exerts multiple deleterious effects on human organism, especially on fertility, pregnancy, central nervous system and bone marrow. 相似文献
109.
Rechberger T Tomaszewski J Pieprzowska-Białek A Kulik-Rechberger B Skorupski P 《Contraception》2004,69(6):477-480
Resistin is a hormone secreted by adipose tissue that could be involved in the development of insulin resistance. Previous studies confirmed that endogenous sex steroids may influence serum resistin concentration in women. The aim of our study was to investigate the influence of combined oral contraceptives containing desogestrel or gestodene on circulating levels of resistin. Fifty-three women were enrolled in the study. Thirteen patients received 20 μg ethinylestradiol/150 μg desogestrel, 15 women were treated with 20 μg ethinylestradiol/75 μg gestodene, 11 with 30 μg ethinylestradiol/150 μg desogestrel and 14 with 30 μg ethinylestradiol/75 μg gestodene. Blood samples for estimation of serum resistin and insulin levels were drawn before administration of oral contraceptive and after 6 cycles of therapy. We found that serum resistin level remained unchanged in women receiving ethinylestradiol/desogestrel and was reduced in women treated with formulations containing gestodene. We conclude that ethinylestradiol combined with desogestrel or gestodene is unlikely to induce insulin resistance through resistin pathway. 相似文献
110.