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101.
102.
Jiménez Isabel Carabia Júlia Bobillo Sabela Palacio Carles Abrisqueta Pau Pagès Carlota Nieto Juan C. Castellví Josep Martínez-Ricarte Francisco Escoda Lourdes Perla Cristóbal Céspedes Torrez Dennis H. Boix Joan Purroy Noelia Puigdefàbregas Lluís Seoane Joan Bosch Francesc Crespo Marta 《Journal of neuro-oncology》2020,149(1):13-25
Journal of Neuro-Oncology - Patients diagnosed with primary central nervous system lymphoma (PCNSL) often face dismal outcomes due to the limited availability of therapeutic options. PCNSL cells... 相似文献
103.
Puig N de la Rubia J Jarque I Salavert M Montesinos P Sanz J Martín G Sanz G Cantero S Lorenzo I Sanz MA 《International journal of hematology》2007,86(2):186-192
Infectious complications are a major cause of morbidity and mortality in patients who undergo autologous stem cell transplantation (ASCT). We examined 476 patients with hematologic malignancies (401) or solid tumors (75) who underwent ASCT between February 1990 and May 2005. Anti-infectious prophylaxis consisted of different combinations of ciprofloxacin, cotrimoxazole, fluconazole, aerosolized amphotericin B, acyclovir, and intravenous immunoglobulins. Overall, 454 patients (95%) developed fever in the first 60 days after ASCT. In the majority of patients, initial antibiotic therapy consisted of broad-spectrum beta-lactamic with or without amikacin. A glycopeptide was administered as initial therapy in 86 cases. Overall, there were 132 (29%) clinically documented infections (37 pneumonias), 79 (17%) microbiologically documented infections (65 bacteremias), and 243 (54%) fevers of unknown origin. Coagulase-negative staphylococci (18, 25%) and E coli (18, 25%) were the organisms most frequently isolated. The pattern of infection did not change throughout the study except for a significantly higher incidence of bacteremia due to gram-positive bacteria in the first 5 years of the study. Infection-related mortality was 5% (21 cases), with pneumonia the most frequent cause of death. ASCT should be considered a low-risk procedure, although new therapeutic approaches for patients developing severe respiratory infections are still needed. 相似文献
104.
Lukas Chavez Yun Huang Khai Luong Suneet Agarwal Lakshminarayan M. Iyer William A. Pastor Virginia K. Hench Sylvia A. Frazier-Bowers Evgenia Korol Shuo Liu Mamta Tahiliani Yinsheng Wang Tyson A. Clark Jonas Korlach Patricia J. Pukkila L. Aravind Anjana Rao 《Proceedings of the National Academy of Sciences of the United States of America》2014,111(48):E5149-E5158
105.
Del Ojo JL Moya F Villalba J Sanz O Pavón R Garcia D Pastor L 《Pacing and clinical electrophysiology : PACE》2005,28(4):274-278
Magnetic resonance imaging (MRI) is currently contraindicated in cardiac pacemaker (PM) recipients. The objectives of this prospective study were to (1) reassess the risks of performing an MRI scan in patients with PM, (2) compared the pacing functions before and after the exposure to MRI, and (3) monitor the development of possible adverse effects. Thirteen patients implanted with an Affinity DR model 5330 PMs (St. Jude Medical) connected to a Tendril model 1388 leads (St. Jude Medical) underwent 2.0 T-MRI for a variety of indications. All patients displayed a stable spontaneous rhythm at the time of the MRI scan and were not considered to be PM-dependent. The sensing and pacing functions were analyzed and the impedance of both leads was measured before and after the scan. The MRI scan was performed with all PM programmed in DDD mode. The sensing configuration was bipolar. All patients were monitored utilizing a standard electrocardiographic monitor and direct verbal communication. PM Inhibition, asynchronous pacing, or inappropriately rapid pacing was not observed. No patient reported discomfort, heat, or motion sensation at the PM implant site. There were no significant differences in the sensing, stimulation, AutoCapture threshold, and lead impedance measurements before and after MRI. The results of this study suggest that performing 2.0 T-MRI scans in patients with Affinity DR model 5330 PM connected to a Tendril model 1388 lead is safe. 相似文献
106.
Serena C Mariné M Pastor FJ Nolard N Guarro J 《The Journal of antimicrobial chemotherapy》2005,55(6):1020-1023
OBJECTIVES: The infections caused by basidiomycetous yeasts are often difficult to resolve. Combined therapy might be useful in those severe cases where a monotherapy was ineffective. The aim of this study was to evaluate the in vitro activity of combinations of micafungin with amphotericin B or fluconazole, itraconazole, voriconazole and ravuconazole against isolates of Trichosporon, Rhodotorula and Sporobolomyces. METHODS: Twenty-seven clinical isolates were tested, i.e. 10 of Trichosporon asahii, two of Trichosporon mucoides, five of Sporobolomyces salmonicolor and 10 of Rhodotorula glutinis. Drug interactions were assessed by the chequerboard technique using the NCCLS microdilution method (M27-A2). The fractional inhibitory concentration index (FICI) was used to classify drug interactions. Results were interpreted as follows: synergy (FICI < or =0.5), no interaction (FICI >0.5 and < or =4.0), or antagonism (FICI >4.0). RESULTS: Micafungin combined with amphotericin B showed the highest percentage of synergic interactions (78%) followed by micafungin/ravuconazole and micafungin/itraconazole (48% for each), and micafungin/fluconazole and micafungin/voriconazole (34% for each). Antagonism was not observed in any case. CONCLUSIONS: Some of the combinations tested, especially micafungin/amphotericin B, have potential for the treatment of basidiomycetous yeast infections. 相似文献
107.
108.
Detection of peripheral embolic consolidations using contrast‐enhanced ultrasonography in patients with no evidence of pulmonary embolism on computed tomography: A pilot study 下载免费PDF全文
109.
110.
Pau Golanó Jordi Vega Peter A. J. de Leeuw Francesc Malagelada M. Cristina Manzanares Víctor Götzens C. Niek van Dijk 《Knee surgery, sports traumatology, arthroscopy》2010,18(5):557-569
Understanding the anatomy of the ankle ligaments is important for correct diagnosis and treatment. Ankle ligament injury is
the most frequent cause of acute ankle pain. Chronic ankle pain often finds its cause in laxity of one of the ankle ligaments.
In this pictorial essay, the ligaments around the ankle are grouped, depending on their anatomic orientation, and each of
the ankle ligaments is discussed in detail. 相似文献