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41.
Bhabatosh?BiswasEmail author Dipayan?Ghosh Rupak?Bhattacharjee Ashis?Patra Subir?Basuthakur Rajarshi?Basu 《Indian Journal of Thoracic and Cardiovascular Surgery》2005,21(2):164-166
Background With the introduction of video imaging technique in late 1980s the field of thoracoscopy was expanded into video assisted
thoracic surgery (VATS) in 1990. VATS has several unique advantages like reducing repiratory complications, hospital stay
and post operative pain due to avoidance of thoracotomy/sternotomy. It is indicated in almost all thoracic surgical procedures-both
diagnostic and therapeutic. VATS thymectomy is being practised more and more replacing conventional thymectomy with thoracotomy/sternotomy.
Methods From 2000 to 2003 we have performed 22 cases of VATS thymectomy in Myesthenia Gravis. Surgery was performed in supine decubitus
under General anaesthesia with Double Lumen E T Tube for epsilateral Lung Collapse. Three ports were made on the right chest
at 2nd space parasternal, 4th space anterior axillary line and at 5th space just below the nipple. At the end of the procedure
a chest drain was introduced through the lowest port.
Results Out of 22 patients 12 were females and 10 males. Median age was 36 years (Range 16 years to 64 years). Median operating time
was 2 hours and drainage was 200 ml. Median ventillation time was 6 hours. Median hospital stay was five days. There was no
mortality and no major complications.
Conclusion VATS thymectomy is a suitable alternative to conventional thymectomy with thoracotomy/sternotomy. Results are comparable.
VATS is now developing into an exciting adjunct in thoracic surgery. The morbidity associated with this procedure is extremely
low. VATS has become an essential component of all thoracic surgical units and more and more thoracic surgical dieases will
be managed with this minimally invasive technique in future. 相似文献
42.
43.
A pair of female thoraco-omphalopagus twins, with two pairs of lungs, common diaphragm and separate pleural cavities was separated
at the age of 51/2 months after a parasitic relationship had developed between them. Before separation both the babies developed
recurrent respiratory tract infection and frequent diarrhea. They were treated with medical therapy and made fit for anesthesia.
The combined weight of the twins was 41/2 kg at birth and the combined weight at the time of separation was 91/2 kg. One baby
was smaller in growth compared to the other baby. The closure of anterior abdominal wall was difficult in both babies. However,
we could close it without use of any biodegrActable patches or tissue expander. Both the babies survived and are doing well
after 3 months of separation. 相似文献
44.
Wedged-shaped lesions at the cemento-enamel junction of teeth have been attributed primarily to biomechanical loading forces that cause flexure and failure of enamel and dentin. This theory, termed abfraction, remains controversial. This review examined studies on mechanical properties of enamel and dentin and studies on bite forces and mastication as background information. Abfraction is based principally on a few early finite element analysis and photoelastic models showing stress concentration at the dental cervical area without actually showing enamel and dentin fracture. However, a review of more recent dental stress analyses has been contradictory. Particularly, analyses of the periodontal ligament and alveolar bone, not modeled in previous studies, have shown that those structures may dissipate occlusal loading forces from the cervical areas. In addition, some models may not fully represent intricate dental anatomy and complex occlusal function. Therefore, the key basis of the abfraction theory may be flawed. 相似文献
45.
Vanadium--an element of atypical biological significance 总被引:9,自引:0,他引:9
Mukherjee B Patra B Mahapatra S Banerjee P Tiwari A Chatterjee M 《Toxicology letters》2004,150(2):135-143
The biological image of the transition element vanadium ferments a great deal of contradiction-from toxicity to essentiality. Importance of this element as micro-nutrient is yet to be unequivocally accepted by biologists and biomedical scientists. In spite of toxicity, it seems interesting to analyze the different biological roles of the element. Vanadium compounds have been proven to be associated with various implications in the pathogenesis of some human diseases and also in maintaining normal body functions. Salts of vanadium interfere with an essential array of enzymatic systems such as different ATPases, protein kinases, ribonucleases and phosphatases. While vanadium deficiency accounts for several physiological malfunctionings including thyroid, glucose and lipid metabolism, etc., several genes are regulated by this element or by its compounds, which include genes for tumor necrosis factor-alpha (TNF-alpha), Interleukin-8 (IL-8), activator protein-1 (AP-1), ras, c-raf-1, mitogen activated protein kinase (MAPK), p53, nuclear factors-kappaB, etc. All these seem to be not far from its recognition as an element of pharmacological and nutritional significance, which is revealed through its increasing therapeutic uses in diabetes. Vanadium is also emerging as a potent anti-carcinogenic agent. This review summarizes the developments related to vanadium biology as a whole by analyzing the general biochemical functions of vanadium. 相似文献
46.
Meurette G Marret O Léauté F Costargent A Patra P Chaillou P 《Annales de chirurgie》2003,128(5):329-332
A 39-years-old woman was admitted with pelvic pain and fever occurring one month after a caesarean. An echography-doppler and an abdominal tomodensitometry were performed. Thrombophlebitis of the right ovarian vein was diagnosed with extension of a floating thrombus into the inferior vena cava. We decided to perform a surgical thrombectomy due to a pulmonary embolism which occurred while the patient was under heparin and antibiotic treatment. A temporary percutaneous caval filter was successfully used in the peri-operative period, preventing a second embolism. This observation focuses on a rare pathology occurring in young women and emphasises the safe use and removal of a temporary percutaneous caval filter in the peri-operative period. 相似文献
47.
Varying degrees of lead (Pb) poisoning was recorded in cows and buffaloes near a primary lead-zinc smelter in India. Affected animals had history of clinical signs characterized by head pressing, violent movement, blindness and salivation. These animals revealed considerably high lead levels in blood (1.43 +/- 0.07 ppm) and milk (0.75 +/- 0.19 ppm). Animals from the same place without the history of clinical signs suggestive of Pb poisoning recorded lower blood Pb levels than the affected animals; however, their blood Pb was higher than that reported for cattle in rural and urban areas of India. Affected animals also carried high levels of cadmium (Cd) in blood (0.11 +/- 0.01 ppm) and milk (0.05 +/- 0.01 ppm). These values were considerably higher than those for rural cattle in India. The findings indicated varying degrees of exposure of animals to Pb and Cd in the vicinity of the smelter. 相似文献
48.
Effect of thiamine hydrochloride on lead induced lipid peroxidation in rat liver and kidney 总被引:1,自引:0,他引:1
Thiamine hydrochloride was studied on lead-induced endogenous lipid peroxidation in rat hepatic and renal tissues following po doses of 2.73 mg lead/kg bw for 6 w. Simultaneous use of 25 mg thiamine hydrochloride/kg bw po reduced lead accumulation in liver and kidneys. There were significant decreases in endogenous lipid peroxide in liver and kidney from thiamine hydrochloride-treated rats. Histopathological lesions in thiamine-treated livers and kidneys were milder in comparison to lesions in untreated Pb-exposed animals. This indicates the prophylactic potential of thiamine for lead-induced lipid peroxidation. 相似文献
49.
50.
Several reports have indicated that the sewage-fed vegetables of the Dhapa area, near the city of Calcutta, contain a very high amount of heavy metals. Currently 800 ha of land is being utilised throughout the year to cultivate more than eight types of vegetables, with a production of about 147 tonnes per day. A major population of Calcutta consumes these vegetables grown in the Dhapa area. Recently there has been huge pressure on the State Government to ban vegetables grown in the Dhapa area for human consumption. For this reason, we have studied the genotoxic effects of some of the most commonly used vegetable extracts from the Dhapa area after in vivo acute exposure in mice as measured by chromosomal aberrations (CA) and sister chromatid exchanges (SCE) to find out the minimum threshold dose to induce CA and SCE. Three different concentrations of the three most commonly used vegetable extracts (cauliflower, spinach, radish) were fed by gavage to mice for the study of CA and SCE. A significant increase in CA was observed only at the highest concentration of all the vegetable extract-treated groups when compared with the solvent control. A significant increase in SCE were observed in the middle and high doses of spinach and only the high dose of cauliflower and radish extract-treated series when compared with distilled water control. The lowest dose was equivalent to approximately 1 kg of vegetables consumed by a human (60 kg body weight) in a day. The middle and high doses of each vegetable extract were much higher than the normal amount of vegetables that a human can consume per day. So the minimum dose for inducing SCE and CA was much higher than the amount a human can consume in a day. Therefore this study indicates that these vegetables are safe for human consumption up to a certain limit, and attention should be given to reducing the heavy metal contents in the soil and sewage of the Dhapa area to thus reduce the heavy metal concentrations in the vegetables. 相似文献